Protein kinases in complex with 8RC (Naquotinib)

Total number of genes: 1
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 1 5Y9TA
DFGin BLBplus 4 7LG8A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5Y9TA 3.25 Active DFGin BLAminus in-in in-in 8RC Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8B 2.93 Inactive DFGin BLBplus out-out none-out VNS 8RC Type1.5_Front Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8A 2.93 Inactive DFGin BLBplus out-out out-out VNS 8RC Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8C 2.93 Inactive DFGin BLBplus out-out out-out VNS 8RC Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8D 2.93 Inactive DFGin BLBplus out-out none-out VNS 8RC Type3 Type1

Protein kinases in complex with 8RC

Total number of genes: 1
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 1 5Y9TA
DFGin BLBplus 4 7LG8A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5Y9TA 3.25 Active DFGin BLAminus in-in in-in 8RC Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8B 2.93 Inactive DFGin BLBplus out-out none-out VNS 8RC Type1.5_Front Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8A 2.93 Inactive DFGin BLBplus out-out out-out VNS 8RC Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8C 2.93 Inactive DFGin BLBplus out-out out-out VNS 8RC Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8D 2.93 Inactive DFGin BLBplus out-out none-out VNS 8RC Type3 Type1

Protein kinases in complex with 8RC

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type