8KH9

FGFR4 (Fibroblast growth factor receptor 4)
Group: TYR
Uniprot: FGFR4_HUMAN
Organism: Homo sapiens
Domain boundary: 467 - 745
Resolu: 1.42

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus in-in out-out VVW Type1 454 - 752 0
Representative sequence - Chain A
463 473 483 493
LPLDPLWEFP RDRLVLGKPL GEGAFGQVVR AEAFGMDPAR
503 513 523 533
PDQASTVAVK MLKDNASDKD LADLVSEMEV MKLIGRHKNI
543 553 563 573
INLLGVCTQE GPLYVIMECA AKGNLREFLR ARRPPGPDLS
583 593 603 613
PDGPRSSEGP LSFPVLVSCA YQVARGMQYL ESRKCIHRDL
623 633 643 653
AARNVLVTED NVMKIADFGL ARGVHHIDYY KKTSNGRLPV
663 673 683 693
KWMAPEALFD EVYTHQSDVW SFGILLWEIF TLGGSPYPGI
703 713 723 733
PVEELFSLLR EGHRMDRPPH CPPELYGLMR ECWHAAPSQR
743 753
PTFKQLVEAL DKVLLAVSEe
Lower-case residues are disordered in structure.
Mutations: C477A,V550M,R664E
Phosphorylation: None