TYR_FGFR4 (Fibroblast growth factor receptor 4)

Total number of chains: 56
Active chains: 2
Family: TYR
Uniprot: FGFR4_HUMAN
Kinase Domain Residues: 467 - 745
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 42 75.0% 8KH8A
DFGin None 4 7.1% 4TYEA
DFGout BBAminus 4 7.1% 4UXQA
DFGin BLAminus 2 3.6% AF-P22455-K1A
DFGin BLBplus 2 3.6% 8KH9A
DFGout None 1 1.8% 4QRCA
None None 1 1.8% 5NUDB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P22455-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 459 - 753 0 None None Fibroblast growth factor receptor 4
AF-P22455-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 459 - 753 0 None None Fibroblast growth factor receptor 4
4QQJA 1.682 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 454 - 752 0 None C477A,V550L,R664E Fibroblast growth factor receptor 4
4QQTA 1.501 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 454 - 750 0 None C477A,R664E Fibroblast growth factor receptor 4
4TYGA 2.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 447 - 751 0 None None Fibroblast growth factor receptor 4
7WCXA 2.175 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 90F Type1 453 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4
7YBXA 2.233 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IH7 Type1 453 - 752 0 None V550M,R664E Fibroblast growth factor receptor 4
7WCWA 2.317 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 90F Type1 453 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4
7YBPA 2.243 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IH7 Type1 453 - 752 0 None V550L,R664E Fibroblast growth factor receptor 4
8KH8A 1.49 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VVW Type1 453 - 751 0 None C477A,V550L,R664E Fibroblast growth factor receptor 4
6JPJA 2.638 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa FGF Type1 454 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4
9K0IA 2.236 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa A1EEW Type1 453 - 752 0 None None Fibroblast growth factor receptor 4
9K0JA 2.068 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1EEX Type1 453 - 752 0 None None Fibroblast growth factor receptor 4
8W5CA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa VZO Type1 453 - 752 0 None None Fibroblast growth factor receptor 4
8W5CB 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa VZO Type1 453 - 752 0 None None Fibroblast growth factor receptor 4
7VJLA 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa 7IF Type1 454 - 753 0 None None Fibroblast growth factor receptor 4
7VJLB 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa 7IF Type1 453 - 753 0 None None Fibroblast growth factor receptor 4
6YI8A 2.13 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa FGF Type1 453 - 753 0 None None Fibroblast growth factor receptor 4
6YI8B 2.13 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa FGF Type1 451 - 752 0 None None Fibroblast growth factor receptor 4
5NUDA 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-none none-none TYR APEdihe_niiai APEdist_aaaa 99K Type1 453 - 753 0 None None Fibroblast growth factor receptor 4
4TYIA 3.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-none TYR APEdihe_nniai APEdist_aaaa 38O Type1 447 - 750 0 None None Fibroblast growth factor receptor 4
7WCTA 2.106 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 90F Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4
7YBOA 2.307 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IH7 Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4
7YC1A 2.535 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IIQ Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4
7YC3A 1.987 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IIW Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4
8KH6A 1.62 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VVI Type1 454 - 750 0 None R664E Fibroblast growth factor receptor 4
8KH7A 1.52 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VVW Type1 454 - 751 0 None R664E Fibroblast growth factor receptor 4
6IUOA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa AWX Type1 445 - 750 0 None R664E Fibroblast growth factor receptor 4
6IUPA 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa AX0 Type1 452 - 750 0 None R664E Fibroblast growth factor receptor 4
4XCUA 1.71 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 40M Type1.5_Back 453 - 751 0 None L449M Fibroblast growth factor receptor 4
6NVGA 1.99 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL8 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4
6NVHA 1.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa XL6 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4
6NVIA 2.117 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa XL7 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4
6NVJA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL5 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4
6NVKA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL9 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4
6V9CA 1.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa QS7 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4
7DTZA 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa HHL Type1.5_Back 453 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4
6JPEA 1.601 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa BYU Type1.5_Back 452 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4
5NWZB 2.37 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4
7F3MA 2.289 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa GX3 Type1.5_Back 453 - 753 0 None R664E Fibroblast growth factor receptor 4
7V29A 1.983 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4
7V29B 1.983 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4
8XLQA 1.95 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1LVQ Type1.5_Back 453 - 751 0 None R664E Fibroblast growth factor receptor 4
4QQCA 2.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa 37O Type1.5_Back 445 - 750 0 None R664E Fibroblast growth factor receptor 4
8KH9A 1.42 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VVW Type1 454 - 752 0 None C477A,V550M,R664E Fibroblast growth factor receptor 4
5NWZA 2.37 Inactive DFGin‑BLBplus DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4
4TYEA 2.8 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 451 - 753 0 None None Fibroblast growth factor receptor 4
5XFJA 3.25 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa 6LF Type1 453 - 750 0 None V550M Fibroblast growth factor receptor 4
5XFFA 2.7 Inactive DFGin‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa 6LF Type1 453 - 750 0 None V550L Fibroblast growth factor receptor 4
5JKGA 2.352 Inactive DFGin‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa 6LF Type1 453 - 750 0 None None Fibroblast growth factor receptor 4
4QQ5A 2.203 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa 37O Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4
4R6VA 2.353 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa FI3 Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4
4UXQA 1.85 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa 0LI Type2 452 - 750 0 None C477A Fibroblast growth factor receptor 4
4TYJA 2.45 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa 0LI Type2 447 - 753 0 None None Fibroblast growth factor receptor 4
4QRCA 1.901 Inactive DFGout‑None DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 0LI Type2 454 - 750 0 None C477A,R664E Fibroblast growth factor receptor 4
5NUDB 2.5 Inactive None‑None DFGAsp-rot-none in-in none-none TYR APEdihe_niiai APEdist_aaaa 99K Type1 449 - 750 0 None None Fibroblast growth factor receptor 4

TYR_FGFR4 (Fibroblast growth factor receptor 4)

Total number of chains: 56
Active chains: 2
Family: TYR
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 42 75.0% 8KH8A
DFGin None 4 7.1% 4TYEA
DFGout BBAminus 4 7.1% 4UXQA
DFGin BLAminus 2 3.6% AF-P22455-K1A
DFGin BLBplus 2 3.6% 8KH9A
DFGout None 1 1.8% 4QRCA
None None 1 1.8% 5NUDB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Hover over column headers for tooltip help

UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
FGFR4_HUMAN AF-P22455-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 459 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN AF-P22455-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 459 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 4QQJA 1.682 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 454 - 752 0 None C477A,V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 4QQTA 1.501 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa No_ligand No_ligand 454 - 750 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 4TYGA 2.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 447 - 751 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7WCXA 2.175 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 90F Type1 453 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7YBXA 2.233 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IH7 Type1 453 - 752 0 None V550M,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7WCWA 2.317 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 90F Type1 453 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7YBPA 2.243 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IH7 Type1 453 - 752 0 None V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 8KH8A 1.49 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VVW Type1 453 - 751 0 None C477A,V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 6JPJA 2.638 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa FGF Type1 454 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 9K0IA 2.236 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-out TYR APEdihe_iioai APEdist_aaaa A1EEW Type1 453 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 9K0JA 2.068 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa A1EEX Type1 453 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 8W5CA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa VZO Type1 453 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 8W5CB 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa VZO Type1 453 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7VJLA 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa 7IF Type1 454 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7VJLB 2.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa 7IF Type1 453 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 6YI8A 2.13 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa FGF Type1 453 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 6YI8B 2.13 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa FGF Type1 451 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 5NUDA 2.5 Inactive DFGin‑BLAplus DFGAsp-rot-out in-none none-none TYR APEdihe_niiai APEdist_aaaa 99K Type1 453 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 4TYIA 3.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-out out-none TYR APEdihe_nniai APEdist_aaaa 38O Type1 447 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7WCTA 2.106 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 90F Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7YBOA 2.307 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IH7 Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7YC1A 2.535 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IIQ Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7YC3A 1.987 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa IIW Type1 453 - 752 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 8KH6A 1.62 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VVI Type1 454 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 8KH7A 1.52 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VVW Type1 454 - 751 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 6IUOA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa AWX Type1 445 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 6IUPA 2.0 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa AX0 Type1 452 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 4XCUA 1.71 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 40M Type1.5_Back 453 - 751 0 None L449M Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 6NVGA 1.99 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL8 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 6NVHA 1.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa XL6 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 6NVIA 2.117 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-none TYR APEdihe_nniai APEdist_aaaa XL7 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 6NVJA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL5 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 6NVKA 2.3 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_nnnai APEdist_aaaa XL9 Type1.5_Back 453 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 6V9CA 1.9 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa QS7 Type1.5_Back 453 - 751 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7DTZA 2.01 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa HHL Type1.5_Back 453 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 6JPEA 1.601 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa BYU Type1.5_Back 452 - 751 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 5NWZB 2.37 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-none TYR APEdihe_niiai APEdist_aaaa 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7F3MA 2.289 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa GX3 Type1.5_Back 453 - 753 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7V29A 1.983 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 7V29B 1.983 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 5JR Type1.5_Back 454 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 8XLQA 1.95 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_iioai APEdist_aaaa A1LVQ Type1.5_Back 453 - 751 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 4QQCA 2.4 Inactive DFGin‑BLAplus DFGAsp-rot-out in-in none-out TYR APEdihe_nnoai APEdist_aaaa 37O Type1.5_Back 445 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 8KH9A 1.42 Inactive DFGin‑BLBplus DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa VVW Type1 454 - 752 0 None C477A,V550M,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 5NWZA 2.37 Inactive DFGin‑BLBplus DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa 9CT Type1.5_Back 454 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 4TYEA 2.8 Inactive DFGin‑None DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa No_ligand No_ligand 451 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 5XFJA 3.25 Inactive DFGin‑None DFGAsp-rot-out in-out none-none TYR APEdihe_nniai APEdist_aaaa 6LF Type1 453 - 750 0 None V550M Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 5XFFA 2.7 Inactive DFGin‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa 6LF Type1 453 - 750 0 None V550L Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 5JKGA 2.352 Inactive DFGin‑None DFGAsp-rot-out in-in none-none TYR APEdihe_nniai APEdist_aaaa 6LF Type1 453 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 4QQ5A 2.203 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-out TYR APEdihe_nnoai APEdist_aaaa 37O Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 4R6VA 2.353 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in none-none TYR APEdihe_nnnai APEdist_aaaa FI3 Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 4UXQA 1.85 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-out TYR APEdihe_iioai APEdist_aaaa 0LI Type2 452 - 750 0 None C477A Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 4TYJA 2.45 Inactive DFGout‑BBAminus DFGAsp-rot-in in-in out-none TYR APEdihe_nniai APEdist_aaaa 0LI Type2 447 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 4QRCA 1.901 Inactive DFGout‑None DFGAsp-rot-out in-in out-out TYR APEdihe_iioai APEdist_aaaa 0LI Type2 454 - 750 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
FGFR4_HUMAN 5NUDB 2.5 Inactive None‑None DFGAsp-rot-none in-in none-none TYR APEdihe_niiai APEdist_aaaa 99K Type1 449 - 750 0 None None Fibroblast growth factor receptor 4 Homo sapiens

TYR_FGFR4 (Fibroblast growth factor receptor 4)

Total number of chains: 0
Active chains: 0
Family: TYR
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism