Ligand: IXR

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 8TO4C
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 8TO4C 2.99 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, IXR ATPlike, Type3 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO4D 2.99 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, IXR ATPlike, Type3 702 - 1005 0 None T790M,V948R Epidermal growth factor receptor

Ligand: IXR

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 8TO4C
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 8TO4C 2.99 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, IXR ATPlike, Type3 702 - 1013 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO4D 2.99 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai ANP, IXR ATPlike, Type3 702 - 1005 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: IXR

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism