| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 6V5PA | 2.3 | Inactive | DFGin‑BLBplus | out-out | out-out | QP4 | Type1 | 701 - 1014 | 0 | None | T790M,V948R | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6V5PB | 2.3 | Inactive | DFGin‑BLBtrans | out-out | out-out | QP4 | Type1 | 701 - 1012 | 13 | None | T790M,V948R | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6V5PC | 2.3 | Inactive | DFGin‑BLBtrans | out-out | out-none | QP4 | Type1 | 701 - 1008 | 13 | None | T790M,V948R | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6V5PD | 2.3 | Inactive | DFGin‑BLBtrans | out-out | out-out | QP4 | Type1 | 701 - 1008 | 0 | None | T790M,V948R | Epidermal growth factor receptor |
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 6V5PA | 2.3 | Inactive | DFGin‑BLBplus | out-out | out-out | QP4 | Type1 | 701 - 1014 | 0 | None | T790M,V948R | Epidermal growth factor receptor | Homo sapiens |
| TYR | EGFR | EGFR_HUMAN | 6V5PB | 2.3 | Inactive | DFGin‑BLBtrans | out-out | out-out | QP4 | Type1 | 701 - 1012 | 13 | None | T790M,V948R | Epidermal growth factor receptor | Homo sapiens |
| TYR | EGFR | EGFR_HUMAN | 6V5PC | 2.3 | Inactive | DFGin‑BLBtrans | out-out | out-none | QP4 | Type1 | 701 - 1008 | 13 | None | T790M,V948R | Epidermal growth factor receptor | Homo sapiens |
| TYR | EGFR | EGFR_HUMAN | 6V5PD | 2.3 | Inactive | DFGin‑BLBtrans | out-out | out-out | QP4 | Type1 | 701 - 1008 | 0 | None | T790M,V948R | Epidermal growth factor receptor | Homo sapiens |
| Spatial label | Dihedral label | Number of Chains | Representative |
|---|
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|