TYR_PTK6 (Protein-tyrosine kinase 6)

Total number of chains: 14
Active chains: 2
Uniprot: PTK6_HUMAN
Kinase Domain Residues: 191 - 443
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 11 78.6% 6CZ3A
DFGin BLAminus 2 14.3% AF-Q13882-K1A
DFGout BBAminus 1 7.1% 6CZ4A

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PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q13882-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 183 - 451 0 None None Protein-tyrosine kinase 6
AF-Q13882-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 183 - 451 0 None None Protein-tyrosine kinase 6
5D7VA 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6
5D7VB 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6
5D7VC 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6
5D7VD 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6
6CZ2A 2.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oioai APEdist_aaao No_ligand No_ligand 182 - 443 0 PTR342 None Protein-tyrosine kinase 6
5H2UA 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
5H2UB 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
5H2UC 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
5H2UD 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
5DA3A 1.7 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 58V Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6
6CZ3A 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oioai APEdist_aaao FLJ Type1 182 - 443 0 None None Protein-tyrosine kinase 6
6CZ4A 1.5 Inactive DFGout‑BBAminus out-out out-none TYR APEdihe_nnnai APEdist_aaan FKY Type2 183 - 443 0 None None Protein-tyrosine kinase 6

TYR_PTK6 (Protein-tyrosine kinase 6)

Total number of chains: 14
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 11 78.6% 6CZ3A
DFGin BLAminus 2 14.3% AF-Q13882-K1A
DFGout BBAminus 1 7.1% 6CZ4A

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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
PTK6_HUMAN AF-Q13882-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 183 - 451 0 None None Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN AF-Q13882-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 183 - 451 0 None None Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN 5D7VA 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN 5D7VB 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN 5D7VC 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN 5D7VD 2.33 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao No_ligand No_ligand 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN 6CZ2A 2.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oioai APEdist_aaao No_ligand No_ligand 182 - 443 0 PTR342 None Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN 5H2UA 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN 5H2UB 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN 5H2UC 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN 5H2UD 2.24 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 1N1 Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN 5DA3A 1.7 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oooai APEdist_aaao 58V Type1 185 - 446 0 None C433T Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN 6CZ3A 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oioai APEdist_aaao FLJ Type1 182 - 443 0 None None Protein-tyrosine kinase 6 Homo sapiens
PTK6_HUMAN 6CZ4A 1.5 Inactive DFGout‑BBAminus out-out out-none TYR APEdihe_nnnai APEdist_aaan FKY Type2 183 - 443 0 None None Protein-tyrosine kinase 6 Homo sapiens

TYR_PTK6 (Protein-tyrosine kinase 6)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism