Ligand: BTB

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 8FLNA
DFGin BLAminus 1 25.0% 7X4UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK1 MK01_HUMAN 7X4UA 1.98 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5ID, 8DK, BTB Type1, Allosteric, Allosteric 10 - 359 0 None None Mitogen-activated protein kinase 1
TYR BTK BTK_HUMAN 8FLNA 1.334 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao Y7W, BTB Type1.5_Front, Allosteric 395 - 657 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 8FLLA 1.498 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao Y7W, BTB Type1.5_Front, Allosteric 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6X3PA 1.34 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao UM4, UM4, BTB Type1.5_Front, Allosteric, Type1 394 - 659 0 None None Tyrosine-protein kinase BTK

Ligand: BTB

Total number of chains: 5
Active chains: 0
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 60.0% 8FLNA
DFGin BLAminus 2 40.0% 7X4UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL ROCO4 ROCO4_DICDI 4F1MA 2.04 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo ACP, BTB ATPlike, Allosteric 1019 - 1292 0 None G1179S Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum
CMGC MAPK1 MK01_HUMAN 7X4UA 1.98 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii 5ID, 8DK, BTB Type1, Allosteric, Allosteric 10 - 359 0 None None Mitogen-activated protein kinase 1 Homo sapiens
TYR BTK BTK_HUMAN 8FLNA 1.334 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao Y7W, BTB Type1.5_Front, Allosteric 395 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 8FLLA 1.498 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_oiiai APEdist_aaao Y7W, BTB Type1.5_Front, Allosteric 395 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6X3PA 1.34 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao UM4, UM4, BTB Type1.5_Front, Allosteric, Type1 394 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens

Ligand: BTB

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 4F1MA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL ROCO4 ROCO4_DICDI 4F1MA 2.04 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iioo ACP, BTB ATPlike, Allosteric 1019 - 1292 0 None G1179S Probable serine/threonine-protein kinase roco4 Dictyostelium discoideum