| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | 7X4UA |
| DFGin | BLBplus | 3 | 8FLNA |
| Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CMGC | MAPK1 | MK01_HUMAN | Mitogen-activated protein kinase 1 | 7X4UA | 1.98 | Inactive | DFGin | BLAminus | in-out | in-in | 5ID 8DK BTB | Type1 Allosteric Allosteric |
| TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 8FLNA | 1.334 | Inactive | DFGin | BLBplus | out-out | out-out | Y7W BTB | Type1.5_Front Allosteric |
| TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 8FLLA | 1.498 | Inactive | DFGin | BLBplus | out-none | out-out | Y7W BTB | Type1.5_Front Allosteric |
| TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 6X3PA | 1.34 | Inactive | DFGin | BLBplus | out-out | out-out | UM4 UM4 BTB | Type1.5_Front Allosteric Type1 |
| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 2 | 7X4UA |
| DFGin | BLBplus | 3 | 8FLNA |
| Organism | Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dictyostelium discoideum | TKL | ROCO4 | ROCO4_DICDI | Probable serine/threonine-protein kinase roco4 | 4F1MA | 2.04 | Inactive | DFGin | BLAminus | in-in | in-out | ACP BTB | Type1 Allosteric |
| Homo sapiens | CMGC | MAPK1 | MK01_HUMAN | Mitogen-activated protein kinase 1 | 7X4UA | 1.98 | Inactive | DFGin | BLAminus | in-out | in-in | 5ID 8DK BTB | Type1 Allosteric Allosteric |
| Homo sapiens | TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 8FLNA | 1.334 | Inactive | DFGin | BLBplus | out-out | out-out | Y7W BTB | Type1.5_Front Allosteric |
| Homo sapiens | TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 8FLLA | 1.498 | Inactive | DFGin | BLBplus | out-none | out-out | Y7W BTB | Type1.5_Front Allosteric |
| Homo sapiens | TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 6X3PA | 1.34 | Inactive | DFGin | BLBplus | out-out | out-out | UM4 UM4 BTB | Type1.5_Front Allosteric Type1 |
| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | 4F1MA |
| Organism | Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dictyostelium discoideum | TKL | ROCO4 | ROCO4_DICDI | Probable serine/threonine-protein kinase roco4 | 4F1MA | 2.04 | Inactive | DFGin | BLAminus | in-in | in-out | ACP BTB | Type1 Allosteric |