Protein kinases in complex with KSA

Total number of genes: 5
Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 5 4WSQA
DFGin BLBplus 2 1R0PA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 5M5AA 1.9 None DFGin BLAminus in-in in-none KSA Type1
OTHER AAK1 AAK1_HUMAN AP2-associated protein kinase 1 4WSQA 1.95 Active DFGin BLAminus in-in in-in KSA Type1
OTHER AAK1 AAK1_HUMAN AP2-associated protein kinase 1 4WSQB 1.95 Active DFGin BLAminus in-in in-in KSA Type1
OTHER IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4KIKA 2.83 None DFGin BLAminus in-in none-out KSA Type1
OTHER IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4KIKB 2.83 Active DFGin BLAminus in-in in-in KSA Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQFA 2.7 Inactive DFGin BLBplus out-out out-out KSA Type1
TYR MET MET_HUMAN Hepatocyte growth factor receptor 1R0PA 1.8 Inactive DFGin BLBplus out-out out-out KSA Type1

Protein kinases in complex with KSA

Total number of genes: 5
Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 5 4WSQA
DFGin BLBplus 2 1R0PA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 5M5AA 1.9 None DFGin BLAminus in-in in-none KSA Type1
Homo sapiens OTHER AAK1 AAK1_HUMAN AP2-associated protein kinase 1 4WSQA 1.95 Active DFGin BLAminus in-in in-in KSA Type1
Homo sapiens OTHER AAK1 AAK1_HUMAN AP2-associated protein kinase 1 4WSQB 1.95 Active DFGin BLAminus in-in in-in KSA Type1
Homo sapiens OTHER IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4KIKA 2.83 None DFGin BLAminus in-in none-out KSA Type1
Homo sapiens OTHER IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4KIKB 2.83 Active DFGin BLAminus in-in in-in KSA Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQFA 2.7 Inactive DFGin BLBplus out-out out-out KSA Type1
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 1R0PA 1.8 Inactive DFGin BLBplus out-out out-out KSA Type1

Protein kinases in complex with KSA

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type