Protein kinases in complex with QOM (Trametinib)

Total number of genes: 1
Total number of chains: 1
Spatial Dihedral Chains Representative
DFGin BLBplus 1 7M0YB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0YB 3.45 Inactive DFGin BLBplus out-out out-out ANP QOM Type1 Type3

Protein kinases in complex with QOM

Total number of genes: 2
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGin BLBplus 4 8BW9C
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Drosophila melanogaster STE DSOR1 DSOR1_DROME Dual specificity mitogen-activated protein kinase kinase dSOR1 8BW9C 3.32 Inactive DFGin BLBplus out-out out-out ANP QOM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0YB 3.45 Inactive DFGin BLBplus out-out out-out ANP QOM Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JURC 2.82 Inactive DFGin BLBplus out-out out-out ANP QOM Type1 Type1
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUXC 3.34 Inactive DFGin BLBplus out-out out-out ANP QOM Type1 Type3

Protein kinases in complex with QOM

Total number of genes: 2
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLBplus 3 8BW9C
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Drosophila melanogaster STE DSOR1 DSOR1_DROME Dual specificity mitogen-activated protein kinase kinase dSOR1 8BW9C 3.32 Inactive DFGin BLBplus out-out out-out ANP QOM Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JURC 2.82 Inactive DFGin BLBplus out-out out-out ANP QOM Type1 Type1
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUXC 3.34 Inactive DFGin BLBplus out-out out-out ANP QOM Type1 Type3