Ligand: VNS

Total number of chains: 19
Spatial label Dihedral label Number of Chains Representative
DFGin BLBplus 19 7JXQB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 7JXQB 1.83 Inactive DFGin‑BLBplus out-out out-none ANP, VNS Type1, Type3 701 - 1007 10 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXQD 1.83 Inactive DFGin‑BLBplus out-out out-none ANP, VNS Type1, Type3 700 - 1007 10 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWA 2.5 Inactive DFGin‑BLBplus out-out none-out YY3, VNS Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWB 2.5 Inactive DFGin‑BLBplus out-out none-none YY3, VNS Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWC 2.5 Inactive DFGin‑BLBplus out-out out-none YY3, VNS Type1, Type3 700 - 1007 15 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWD 2.5 Inactive DFGin‑BLBplus out-out none-out YY3, VNS Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1IA 3.202 Inactive DFGin‑BLBplus out-out none-none ANP, VNS Type1, Type3 700 - 1007 17 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LG8B 2.93 Inactive DFGin‑BLBplus out-out none-out VNS, 8RC Type1.5_Front, Type1 702 - 1002 15 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXQA 1.83 Inactive DFGin‑BLBplus out-out out-out VNS, ANP Type3, Type1 700 - 1007 12 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXQC 1.83 Inactive DFGin‑BLBplus out-out out-none VNS, ANP Type3, Type1 700 - 1007 10 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LG8A 2.93 Inactive DFGin‑BLBplus out-out out-out VNS, 8RC Type3, Type1 702 - 1006 15 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LG8C 2.93 Inactive DFGin‑BLBplus out-out out-out VNS, 8RC Type3, Type1 703 - 1004 15 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LG8D 2.93 Inactive DFGin‑BLBplus out-out none-out VNS, 8RC Type3, Type1 702 - 1003 17 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HA 2.602 Inactive DFGin‑BLBplus out-out none-none VNS, YY3 Type3, Type1 701 - 1007 16 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HB 2.602 Inactive DFGin‑BLBplus out-out none-none VNS, YY3 Type3, Type1 701 - 1008 17 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HC 2.602 Inactive DFGin‑BLBplus out-out none-out VNS, YY3 Type3, Type1 701 - 1007 17 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HD 2.602 Inactive DFGin‑BLBplus out-out out-out VNS, YY3 Type3, Type1 701 - 1007 15 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HE 2.602 Inactive DFGin‑BLBplus out-out none-none VNS, YY3 Type3, Type1 703 - 1007 16 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7K1HF 2.602 Inactive DFGin‑BLBplus out-out none-out VNS, YY3 Type3, Type1 701 - 1007 17 None L858R,V948R Epidermal growth factor receptor

Ligand: VNS

Total number of chains: 19
Spatial label Dihedral label Number of Chains Representative
DFGin BLBplus 19 7JXQB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 7JXQB 1.83 Inactive DFGin‑BLBplus out-out out-none ANP, VNS Type1, Type3 701 - 1007 10 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXQD 1.83 Inactive DFGin‑BLBplus out-out out-none ANP, VNS Type1, Type3 700 - 1007 10 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXWA 2.5 Inactive DFGin‑BLBplus out-out none-out YY3, VNS Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXWB 2.5 Inactive DFGin‑BLBplus out-out none-none YY3, VNS Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXWC 2.5 Inactive DFGin‑BLBplus out-out out-none YY3, VNS Type1, Type3 700 - 1007 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXWD 2.5 Inactive DFGin‑BLBplus out-out none-out YY3, VNS Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1IA 3.202 Inactive DFGin‑BLBplus out-out none-none ANP, VNS Type1, Type3 700 - 1007 17 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7LG8B 2.93 Inactive DFGin‑BLBplus out-out none-out VNS, 8RC Type1.5_Front, Type1 702 - 1002 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXQA 1.83 Inactive DFGin‑BLBplus out-out out-out VNS, ANP Type3, Type1 700 - 1007 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXQC 1.83 Inactive DFGin‑BLBplus out-out out-none VNS, ANP Type3, Type1 700 - 1007 10 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7LG8A 2.93 Inactive DFGin‑BLBplus out-out out-out VNS, 8RC Type3, Type1 702 - 1006 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7LG8C 2.93 Inactive DFGin‑BLBplus out-out out-out VNS, 8RC Type3, Type1 703 - 1004 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7LG8D 2.93 Inactive DFGin‑BLBplus out-out none-out VNS, 8RC Type3, Type1 702 - 1003 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1HA 2.602 Inactive DFGin‑BLBplus out-out none-none VNS, YY3 Type3, Type1 701 - 1007 16 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1HB 2.602 Inactive DFGin‑BLBplus out-out none-none VNS, YY3 Type3, Type1 701 - 1008 17 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1HC 2.602 Inactive DFGin‑BLBplus out-out none-out VNS, YY3 Type3, Type1 701 - 1007 17 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1HD 2.602 Inactive DFGin‑BLBplus out-out out-out VNS, YY3 Type3, Type1 701 - 1007 15 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1HE 2.602 Inactive DFGin‑BLBplus out-out none-none VNS, YY3 Type3, Type1 703 - 1007 16 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7K1HF 2.602 Inactive DFGin‑BLBplus out-out none-out VNS, YY3 Type3, Type1 701 - 1007 17 None L858R,V948R Epidermal growth factor receptor Homo sapiens

Ligand: VNS

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism