TKL_LIMK2 (LIM domain kinase 2)

Total number of chains: 16
Uniprot: LIMK2_HUMAN
Kinase Domain Residues: 331 - 603
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 2 AF-P53671-K1A
DFGin BLBplus 8 8WSWA
DFGout BBAminus 5 7QHGA
DFGout None 1 5NXDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P53671-K1A -1.0 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 323 - 611 0 None None LIM domain kinase 2
AF-P53671-K3A -1.0 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 323 - 611 0 None None LIM domain kinase 2
8WSWA 2.5 Inactive DFGin‑BLBplus out-out out-out LH0 Type1 330 - 632 22 None None LIM domain kinase 2
8WSWB 2.5 Inactive DFGin‑BLBplus out-out out-out LH0 Type1 330 - 632 22 None None LIM domain kinase 2
8WSWC 2.5 Inactive DFGin‑BLBplus out-out out-out LH0 Type1 330 - 632 22 None None LIM domain kinase 2
8WSWD 2.5 Inactive DFGin‑BLBplus out-out out-out LH0 Type1 330 - 632 22 None None LIM domain kinase 2
8S3XA 2.59 Inactive DFGin‑BLBplus out-none out-out A1H41 Type1 334 - 631 21 None None LIM domain kinase 2
8S3XB 2.59 Inactive DFGin‑BLBplus out-none out-out A1H41 Type1 330 - 631 24 None None LIM domain kinase 2
8S3XC 2.59 Inactive DFGin‑BLBplus out-out out-out A1H41 Type1 330 - 631 25 None None LIM domain kinase 2
8S3XD 2.59 Inactive DFGin‑BLBplus out-none out-out A1H41 Type1 331 - 631 26 None None LIM domain kinase 2
7QHGA 1.45 Inactive DFGout‑BBAminus out-out out-out T3B Type2 330 - 632 21 None None LIM domain kinase 2
7QHGB 1.45 Inactive DFGout‑BBAminus out-out out-out T3B Type2 330 - 632 22 None None LIM domain kinase 2
4TPTA 2.6 Inactive DFGout‑BBAminus out-out out-out 35H Type3 330 - 631 23 None None LIM domain kinase 2
4TPTB 2.6 Inactive DFGout‑BBAminus out-out out-out 35H Type3 330 - 632 26 None None LIM domain kinase 2
5NXDB 1.9 Inactive DFGout‑BBAminus out-out out-none 9D8 Type3 330 - 632 32 None None LIM domain kinase 2
5NXDA 1.9 Inactive DFGout‑None out-out out-none 9D8 Type3 330 - 632 32 None None LIM domain kinase 2

TKL_LIMK2 (LIM domain kinase 2)

Total number of chains: 16
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 2 AF-P53671-K1A
DFGin BLBplus 8 8WSWA
DFGout BBAminus 5 7QHGA
DFGout None 1 5NXDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
Homo sapiens LIMK2_HUMAN AF-P53671-K1A -1.0 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 323 - 611 0 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN AF-P53671-K3A -1.0 Active DFGin‑BLAminus in-in in-in No_ligand No_ligand 323 - 611 0 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 8WSWA 2.5 Inactive DFGin‑BLBplus out-out out-out LH0 Type1 330 - 632 22 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 8WSWB 2.5 Inactive DFGin‑BLBplus out-out out-out LH0 Type1 330 - 632 22 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 8WSWC 2.5 Inactive DFGin‑BLBplus out-out out-out LH0 Type1 330 - 632 22 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 8WSWD 2.5 Inactive DFGin‑BLBplus out-out out-out LH0 Type1 330 - 632 22 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 8S3XA 2.59 Inactive DFGin‑BLBplus out-none out-out A1H41 Type1 334 - 631 21 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 8S3XB 2.59 Inactive DFGin‑BLBplus out-none out-out A1H41 Type1 330 - 631 24 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 8S3XC 2.59 Inactive DFGin‑BLBplus out-out out-out A1H41 Type1 330 - 631 25 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 8S3XD 2.59 Inactive DFGin‑BLBplus out-none out-out A1H41 Type1 331 - 631 26 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 7QHGA 1.45 Inactive DFGout‑BBAminus out-out out-out T3B Type2 330 - 632 21 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 7QHGB 1.45 Inactive DFGout‑BBAminus out-out out-out T3B Type2 330 - 632 22 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 4TPTA 2.6 Inactive DFGout‑BBAminus out-out out-out 35H Type3 330 - 631 23 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 4TPTB 2.6 Inactive DFGout‑BBAminus out-out out-out 35H Type3 330 - 632 26 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 5NXDB 1.9 Inactive DFGout‑BBAminus out-out out-none 9D8 Type3 330 - 632 32 None None LIM domain kinase 2
Homo sapiens LIMK2_HUMAN 5NXDA 1.9 Inactive DFGout‑None out-out out-none 9D8 Type3 330 - 632 32 None None LIM domain kinase 2

TKL_LIMK2 (LIM domain kinase 2)

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein