| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | AF-P80192-K1A |
| DFGin | BLBplus | 3 | 4UY9A |
| PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AF-P80192-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 136 - 413 | None | None | 0 |
| 4UY9A | 2.81 | Inactive | DFGin | BLBplus | in-out | out-out | No_ligand | No_ligand | 135 - 447 | None | None | 0 |
| 4UY9B | 2.81 | Inactive | DFGin | BLBplus | in-none | out-out | No_ligand | No_ligand | 135 - 449 | None | None | 0 |
| 3DTCA | 2.6 | Inactive | DFGin | BLBplus | out-out | none-out | VIN | Type1 | 136 - 405 | T312A | None | 13 |
| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | AF-P80192-K1A |
| DFGin | BLBplus | 3 | 4UY9A |
| Organism | UniprotID | PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Homo sapiens | M3K9_HUMAN | AF-P80192-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 136 - 413 | None | None | 0 |
| Homo sapiens | M3K9_HUMAN | 4UY9A | 2.81 | Inactive | DFGin | BLBplus | in-out | out-out | No_ligand | No_ligand | 135 - 447 | None | None | 0 |
| Homo sapiens | M3K9_HUMAN | 4UY9B | 2.81 | Inactive | DFGin | BLBplus | in-none | out-out | No_ligand | No_ligand | 135 - 449 | None | None | 0 |
| Homo sapiens | M3K9_HUMAN | 3DTCA | 2.6 | Inactive | DFGin | BLBplus | out-out | none-out | VIN | Type1 | 136 - 405 | T312A | None | 13 |