Ligand: QP1

Total number of chains: 5
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 6VHPA
DFGin BLBplus 1 6V66D
DFGin BLBtrans 3 6V66A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 6VHPA 3.6 None DFGin‑BLAminus in-in in-none QP1 Type1 696 - 1019 5 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66D 1.79 Inactive DFGin‑BLBplus out-out out-out QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66A 1.79 Inactive DFGin‑BLBtrans out-out out-out QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66B 1.79 Inactive DFGin‑BLBtrans out-out out-out QP1 Type1 701 - 1014 12 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V66C 1.79 Inactive DFGin‑BLBtrans out-out out-none QP1 Type1 701 - 1012 13 None T790M,V948R Epidermal growth factor receptor

Ligand: QP1

Total number of chains: 5
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 6VHPA
DFGin BLBplus 1 6V66D
DFGin BLBtrans 3 6V66A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 6VHPA 3.6 None DFGin‑BLAminus in-in in-none QP1 Type1 696 - 1019 5 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V66D 1.79 Inactive DFGin‑BLBplus out-out out-out QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V66A 1.79 Inactive DFGin‑BLBtrans out-out out-out QP1 Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V66B 1.79 Inactive DFGin‑BLBtrans out-out out-out QP1 Type1 701 - 1014 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V66C 1.79 Inactive DFGin‑BLBtrans out-out out-none QP1 Type1 701 - 1012 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: QP1

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism