Ligand: 7G9

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 100.0% 5P9LA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR BTK BTK_HUMAN 5P9LA 1.25 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao 7G9 Type1 392 - 657 0 None None Tyrosine-protein kinase BTK
TYR EGFR EGFR_HUMAN 7A2AA 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao 57N, 7G9 Type3, Type1 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A2AB 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao 57N, 7G9 Type3, Type1 699 - 984 0 None T790M,V948R Epidermal growth factor receptor

Ligand: 7G9

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 100.0% 5P9LA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR BTK BTK_HUMAN 5P9LA 1.25 Inactive DFGin‑BLBplus out-none out-out TYR APEdihe_niiai APEdist_aaao 7G9 Type1 392 - 657 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR EGFR EGFR_HUMAN 7A2AA 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao 57N, 7G9 Type3, Type1 700 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7A2AB 1.9 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao 57N, 7G9 Type3, Type1 699 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: 7G9

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism