Ligand: VO7

Total number of chains: 5
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 9NM0A
DFGin BLBplus 3 7JXLB
DFGin BLBtrans 1 7JXLA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 9NM0A 2.59 None DFGin‑BLAminus in-in in-none VO7 Type1 697 - 1018 16 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLB 2.4 Inactive DFGin‑BLBplus out-out out-none VO7 Type1 700 - 1005 15 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLC 2.4 Inactive DFGin‑BLBplus out-out out-out VO7 Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLD 2.4 Inactive DFGin‑BLBplus out-out out-none VO7 Type1 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXLA 2.4 Inactive DFGin‑BLBtrans out-out out-none VO7 Type1 701 - 1013 14 None T790M,V948R Epidermal growth factor receptor

Ligand: VO7

Total number of chains: 5
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 9NM0A
DFGin BLBplus 3 7JXLB
DFGin BLBtrans 1 7JXLA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 9NM0A 2.59 None DFGin‑BLAminus in-in in-none VO7 Type1 697 - 1018 16 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXLB 2.4 Inactive DFGin‑BLBplus out-out out-none VO7 Type1 700 - 1005 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXLC 2.4 Inactive DFGin‑BLBplus out-out out-out VO7 Type1 700 - 1007 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXLD 2.4 Inactive DFGin‑BLBplus out-out out-none VO7 Type1 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXLA 2.4 Inactive DFGin‑BLBtrans out-out out-none VO7 Type1 701 - 1013 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: VO7

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism