Ligand: R1L (Rilzabrutinib)

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 100.0% 7L5PA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR BTK BTK_HUMAN 7L5OA 1.21 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao R1L Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7L5PA 2.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao R1L Type1.5_Back 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 7L5PB 2.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao R1L Type1.5_Back 393 - 658 0 None None Tyrosine-protein kinase BTK

Ligand: R1L (Rilzabrutinib)

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 100.0% 7L5PA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR BTK BTK_HUMAN 7L5OA 1.21 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao R1L Type1.5_Back 389 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7L5PA 2.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao R1L Type1.5_Back 392 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 7L5PB 2.14 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao R1L Type1.5_Back 393 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens

Ligand: R1L (Rilzabrutinib)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism