Ligand: P01

Total number of chains: 4
Active chains: 1
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 25.0% 2IZUA
DFGin BLBplus 1 25.0% 2Z7SA
DFGin None 1 25.0% 1YOMB
None None 1 25.0% 1YOMA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC RPS6KA1-1 KS6A1_HUMAN 2Z7SA 2.1 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno P01 Type1 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1
CK1 CSNK1G3 KC1G3_HUMAN 2IZUA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii P01 Type1 36 - 334 0 None None Casein kinase I isoform gamma-3
TYR SRC SRC_HUMAN 1YOMB 2.9 Inactive DFGin‑None in-none none-out TYR APEdihe_nnoai APEdist_aaao P01 Type1 258 - 536 0 None S345N,A370S,Y419W Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 1YOMA 2.9 Inactive None‑None in-none none-out TYR APEdihe_nniai APEdist_aaao P01 Type1 258 - 536 0 None S345N,A370S,Y419W Proto-oncogene tyrosine-protein kinase Src

Ligand: P01

Total number of chains: 4
Active chains: 1
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 25.0% 2IZUA
DFGin BLBplus 1 25.0% 2Z7SA
DFGin None 1 25.0% 1YOMB
None None 1 25.0% 1YOMA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AGC RPS6KA1-1 KS6A1_HUMAN 2Z7SA 2.1 Inactive DFGin‑BLBplus none-none out-out nonTYR APEdihe_aaiii APEdist_nnno P01 Type1 56 - 340 0 None None Ribosomal protein S6 kinase alpha-1 Homo sapiens
CK1 CSNK1G3 KC1G3_HUMAN 2IZUA 1.85 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii P01 Type1 36 - 334 0 None None Casein kinase I isoform gamma-3 Homo sapiens
TYR SRC SRC_HUMAN 1YOMB 2.9 Inactive DFGin‑None in-none none-out TYR APEdihe_nnoai APEdist_aaao P01 Type1 258 - 536 0 None S345N,A370S,Y419W Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 1YOMA 2.9 Inactive None‑None in-none none-out TYR APEdihe_nniai APEdist_aaao P01 Type1 258 - 536 0 None S345N,A370S,Y419W Proto-oncogene tyrosine-protein kinase Src Homo sapiens

Ligand: P01

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism