9AXH

KSR1 (Kinase suppressor of Ras 1)
MAP2K1 (Dual specificity mitogen-activated protein kinase kinase 1)
Pseudokinase
Group: STE TKL
Uniprot: MP2K1_HUMAN KSR1_HUMAN
Organism: Homo sapiens
Domain boundary: 68 - 361 613 - 879
Resolution: 2.81

Chain id Group Gene UniprotID Protein Organism Activity Spatial Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens Inactive DFGin BLBplus out-out out-out A1AHE ANP Type1 Type1 39 - 381 0
B STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens Inactive DFGin BLBplus out-out out-out A1AHE ANP Type1 Type1 38 - 381 0
C TKL KSR1 KSR1_HUMAN Kinase suppressor of Ras 1 Homo sapiens Inactive DFGin BLBplus out-none out-out ANP Type1 614 - 881 7
D TKL KSR1 KSR1_HUMAN Kinase suppressor of Ras 1 Homo sapiens Inactive DFGin BLBplus out-none none-out ANP Type1 613 - 881 13
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
       609        619        629        639 
gvylqewdip feqVELGEPI GQGRWGRVHR GRWHGEVAIR 
       649        659        669        679 
LLEMdghnqd hLKLFKKEVM NYRQTRHENV VLFMGACMNP 
       689        699        709        719 
PHLAIITSFC KGRTLHSFVR DPKTSLDINK TRQIAQEIIK 
       729        739        749        759 
GMGYLHAKGI VHKDLKSKNV FYDNGKVVIT DFGLFgisgv 
       769        779        789        799 
vregrrenQL KLSHDWLCYL APEIVREMTP GKDEDQLPFS 
       809        819        829        839 
KAADVYAFGT VWYELQARDW PLKNQAAEAS IWQIGSGEGM 
       849        859        869        879 
KRVLTSVSLG KEVSEILSAC WAFDLQERPS FSLLMDMLEK 

LPk
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None