Ligand: IRG

Total number of chains: 10
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
None None 4 40.0% 4EH3A
DFGin None 2 20.0% 4EH4A
DFGinter None 2 20.0% 4EHVA
DFGin BLBplus 1 10.0% 4EH2A
DFGout None 1 10.0% 4EH8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK14 MK14_HUMAN 4EH2A 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, 0OK Allosteric, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4DLIA 1.91 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, IRG Allosteric, Allosteric 5 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4EH4A 2.5 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo IRG, 0OL Allosteric, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4EH9A 2.1 Inactive DFGinter‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnoo IRG, 0OQ Allosteric, Type3 5 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4EHVA 1.6 Inactive DFGinter‑None in-none none-out nonTYR APEdihe_aaoii APEdist_nnoo 0SJ, 0SJ, IRG, 0SJ Type3, Allosteric, Allosteric, Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4EH8A 2.2 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, 0OP, 0OP Allosteric, Type3, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4EH5A 2.0 Inactive None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, 0OM Allosteric, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4EH6A 2.1 Inactive None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, 0ON Allosteric, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4EH7A 2.1 Inactive None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, 0OO Allosteric, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4EH3A 2.4 Inactive None‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnoo NAR, IRG Type1, Allosteric 4 - 354 0 None None Mitogen-activated protein kinase 14

Ligand: IRG

Total number of chains: 10
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
None None 4 40.0% 4EH3A
DFGin None 2 20.0% 4EH4A
DFGinter None 2 20.0% 4EHVA
DFGin BLBplus 1 10.0% 4EH2A
DFGout None 1 10.0% 4EH8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK14 MK14_HUMAN 4EH2A 2.0 Inactive DFGin‑BLBplus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, 0OK Allosteric, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4DLIA 1.91 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, IRG Allosteric, Allosteric 5 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4EH4A 2.5 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo IRG, 0OL Allosteric, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4EH9A 2.1 Inactive DFGinter‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnoo IRG, 0OQ Allosteric, Type3 5 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4EHVA 1.6 Inactive DFGinter‑None in-none none-out nonTYR APEdihe_aaoii APEdist_nnoo 0SJ, 0SJ, IRG, 0SJ Type3, Allosteric, Allosteric, Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4EH8A 2.2 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, 0OP, 0OP Allosteric, Type3, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4EH5A 2.0 Inactive None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, 0OM Allosteric, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4EH6A 2.1 Inactive None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, 0ON Allosteric, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4EH7A 2.1 Inactive None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno IRG, 0OO Allosteric, Type1 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4EH3A 2.4 Inactive None‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnoo NAR, IRG Type1, Allosteric 4 - 354 0 None None Mitogen-activated protein kinase 14 Homo sapiens

Ligand: IRG

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism