PDB: 6V6K — TYR EGFR_HUMAN

Total number of chains: 8
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 5 62.5% 6V6KD
DFGin BLBtrans 3 37.5% 6V6KH

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 6V6KA 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KC 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KD 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KF 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KG 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KB 2.2 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nnnai APEdist_aaan QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KE 2.2 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KH 2.2 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_oiiai APEdist_aaao QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor

PDB: 6V6K — TYR EGFR_HUMAN

Total number of chains: 8
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 5 62.5% 6V6KD
DFGin BLBtrans 3 37.5% 6V6KH

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 6V6KA 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KC 2.2 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KD 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KF 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KG 2.2 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KB 2.2 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nnnai APEdist_aaan QQJ Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KE 2.2 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KH 2.2 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_oiiai APEdist_aaao QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

PDB: 6V6K — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism