Ligand: 1FM

Total number of chains: 8
Active chains: 0
Total number of genes: 5
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 5 62.5% 9M1ZC
DFGin BLAminus 1 12.5% 3W55A
DFGin BLBminus 1 12.5% 4GS6A
DFGin BLBplus 1 12.5% 8YP5A
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK1 MK01_HUMAN 3W55A 3.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaooo APEdist_nnoo 1FM Type1 11 - 357 0 None None Mitogen-activated protein kinase 1
STE MAP2K4 MP2K4_HUMAN 8YP5A 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out na-na out-out nonTYR APEdihe_aaoai APEdist_oooo 1FM Type1 80 - 392 0 None None Dual specificity mitogen-activated protein kinase kinase 4
STE MAP2K6 MP2K6_HUMAN 9M1ZA 3.0 Inactive DFGout‑None DFGAsp-rot-out na-na out-out nonTYR APEdihe_aaoao APEdist_iooo 1FM Type1 38 - 334 0 None None Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 9M1ZB 3.0 Inactive DFGout‑None DFGAsp-rot-out na-na out-out nonTYR APEdihe_aaiao APEdist_oooo 1FM Type1 38 - 333 0 None None Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 9M1ZC 3.0 Inactive DFGout‑None DFGAsp-rot-out na-na out-out nonTYR APEdihe_aaoao APEdist_oooo 1FM Type1 38 - 334 0 None None Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 9M1ZD 3.0 Inactive DFGout‑None DFGAsp-rot-out na-na out-out nonTYR APEdihe_aaoao APEdist_iooo 1FM Type1 38 - 334 0 None None Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K7 MP2K7_HUMAN 3WZUA 3.01 Inactive DFGout‑None DFGAsp-rot-out na-na none-out nonTYR APEdihe_aaoai APEdist_nnno 1FM Type1 104 - 402 0 None None Dual specificity mitogen-activated protein kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 4GS6A 2.2 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 1FM Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7

Ligand: 1FM

Total number of chains: 8
Active chains: 0
Total number of genes: 5
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 5 62.5% 9M1ZC
DFGin BLAminus 1 12.5% 3W55A
DFGin BLBminus 1 12.5% 4GS6A
DFGin BLBplus 1 12.5% 8YP5A
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK1 MK01_HUMAN 3W55A 3.0 Inactive DFGin‑BLAminus DFGAsp-rot-in in-in in-out nonTYR APEdihe_aaooo APEdist_nnoo 1FM Type1 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
STE MAP2K4 MP2K4_HUMAN 8YP5A 2.5 Inactive DFGin‑BLBplus DFGAsp-rot-out na-na out-out nonTYR APEdihe_aaoai APEdist_oooo 1FM Type1 80 - 392 0 None None Dual specificity mitogen-activated protein kinase kinase 4 Homo sapiens
STE MAP2K6 MP2K6_HUMAN 9M1ZA 3.0 Inactive DFGout‑None DFGAsp-rot-out na-na out-out nonTYR APEdihe_aaoao APEdist_iooo 1FM Type1 38 - 334 0 None None Dual specificity mitogen-activated protein kinase kinase 6 Homo sapiens
STE MAP2K6 MP2K6_HUMAN 9M1ZB 3.0 Inactive DFGout‑None DFGAsp-rot-out na-na out-out nonTYR APEdihe_aaiao APEdist_oooo 1FM Type1 38 - 333 0 None None Dual specificity mitogen-activated protein kinase kinase 6 Homo sapiens
STE MAP2K6 MP2K6_HUMAN 9M1ZC 3.0 Inactive DFGout‑None DFGAsp-rot-out na-na out-out nonTYR APEdihe_aaoao APEdist_oooo 1FM Type1 38 - 334 0 None None Dual specificity mitogen-activated protein kinase kinase 6 Homo sapiens
STE MAP2K6 MP2K6_HUMAN 9M1ZD 3.0 Inactive DFGout‑None DFGAsp-rot-out na-na out-out nonTYR APEdihe_aaoao APEdist_iooo 1FM Type1 38 - 334 0 None None Dual specificity mitogen-activated protein kinase kinase 6 Homo sapiens
STE MAP2K7 MP2K7_HUMAN 3WZUA 3.01 Inactive DFGout‑None DFGAsp-rot-out na-na none-out nonTYR APEdihe_aaoai APEdist_nnno 1FM Type1 104 - 402 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 4GS6A 2.2 Inactive DFGin‑BLBminus DFGAsp-rot-out in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 1FM Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens

Ligand: 1FM

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism