Ligand: ZL1

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 7MONA
DFGin BLBplus 1 50.0% 7MONB
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
OTHER MLKL MLKL_HUMAN 7MONA 2.23 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ZL1 Type1 191 - 469 0 None None Mixed lineage kinase domain-like protein
TKL RIPK3 RIPK3_HUMAN 7MONB 2.23 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoii APEdist_oooo ZL1 Type1.5_Front 5 - 311 0 TPO224,SEP227 C3S,C110A Receptor-interacting serine/threonine-protein kinase 3

Ligand: ZL1

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 7MONA
DFGin BLBplus 1 50.0% 7MONB
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER MLKL MLKL_HUMAN 7MONA 2.23 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ZL1 Type1 191 - 469 0 None None Mixed lineage kinase domain-like protein Homo sapiens
TKL RIPK3 RIPK3_HUMAN 7MONB 2.23 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaoii APEdist_oooo ZL1 Type1.5_Front 5 - 311 0 TPO224,SEP227 C3S,C110A Receptor-interacting serine/threonine-protein kinase 3 Homo sapiens

Ligand: ZL1

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism