Ligand: 1FV

Total number of chains: 7
Active chains: 2
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 71.4% 6QAUA
DFGin BLBplus 1 14.3% 4IM0A
DFGin None 1 14.3% 4IWQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
OTHER TBK1 TBK1_HUMAN 4IM0A 2.4 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanni APEdist_nnnn 1FV Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1
OTHER TBK1 TBK1_HUMAN 4IWQA 3.0 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aaiii APEdist_nnni 1FV Type1 2 - 657 0 None S172A Serine/threonine-protein kinase TBK1
OTHER ULK1 ULK1_HUMAN 8P5LA 1.836 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1FV Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK1 ULK1_HUMAN 8P5LB 1.836 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1FV Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1
OTHER ULK2 ULK2_HUMAN 6QAUA 2.48 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo 1FV Type1 1 - 275 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QAUB 2.48 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1FV Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2
OTHER ULK2 ULK2_HUMAN 6QAUC 2.48 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanno APEdist_nnnn 1FV Type1 1 - 273 0 None None Serine/threonine-protein kinase ULK2

Ligand: 1FV

Total number of chains: 7
Active chains: 2
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 71.4% 6QAUA
DFGin BLBplus 1 14.3% 4IM0A
DFGin None 1 14.3% 4IWQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER TBK1 TBK1_HUMAN 4IM0A 2.4 Inactive DFGin‑BLBplus out-out none-none nonTYR APEdihe_aanni APEdist_nnnn 1FV Type1 1 - 657 0 None D135N Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER TBK1 TBK1_HUMAN 4IWQA 3.0 Inactive DFGin‑None out-out out-none nonTYR APEdihe_aaiii APEdist_nnni 1FV Type1 2 - 657 0 None S172A Serine/threonine-protein kinase TBK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5LA 1.836 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1FV Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK1 ULK1_HUMAN 8P5LB 1.836 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 1FV Type1 8 - 280 0 TPO180 R245A,E246A Serine/threonine-protein kinase ULK1 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QAUA 2.48 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo 1FV Type1 1 - 275 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QAUB 2.48 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aannn APEdist_nnnn 1FV Type1 1 - 274 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens
OTHER ULK2 ULK2_HUMAN 6QAUC 2.48 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanno APEdist_nnnn 1FV Type1 1 - 273 0 None None Serine/threonine-protein kinase ULK2 Homo sapiens

Ligand: 1FV

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism