Ligand: IYC

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 100.0% 8K78A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR MET MET_HUMAN 8K78A 2.67 Inactive DFGin‑BLBplus out-none out-in TYR APEdihe_iiiai APEdist_aaai IYC Type1 1048 - 1345 0 None None Hepatocyte growth factor receptor

Ligand: IYC

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 33.3% 8K79A
DFGin BLBplus 1 33.3% 8K78A
DFGin None 1 33.3% 8K79B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR SRC SRC_CHICK 8K79A 2.8 None DFGin‑BLAminus in-none in-none TYR APEdihe_nniai APEdist_aaai IYC Type1 257 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 8K79B 2.8 Inactive DFGin‑None in-none out-none TYR APEdihe_nniai APEdist_aaai IYC Type1 269 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR MET MET_HUMAN 8K78A 2.67 Inactive DFGin‑BLBplus out-none out-in TYR APEdihe_iiiai APEdist_aaai IYC Type1 1048 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens

Ligand: IYC

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8K79A
DFGin None 1 50.0% 8K79B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR SRC SRC_CHICK 8K79A 2.8 None DFGin‑BLAminus in-none in-none TYR APEdihe_nniai APEdist_aaai IYC Type1 257 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 8K79B 2.8 Inactive DFGin‑None in-none out-none TYR APEdihe_nniai APEdist_aaai IYC Type1 269 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus