KinCore

Ligand: N7Z

Total number of chains: 2

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLBplus	2	6TFYA

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein
TYR	EGFR	EGFR_HUMAN	6TFYA	1.7	Inactive	DFGin‑BLBplus	out-out	none-out	N7Z	Type1	699 - 982	15	None	T790M,V948R	Epidermal growth factor receptor
TYR	EGFR	EGFR_HUMAN	6TFYB	1.7	Inactive	DFGin‑BLBplus	out-out	none-out	N7Z	Type1.5_Back	699 - 984	17	None	T790M,V948R	Epidermal growth factor receptor

Ligand: N7Z

Total number of chains: 2

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLBplus	2	6TFYA

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism
TYR	EGFR	EGFR_HUMAN	6TFYA	1.7	Inactive	DFGin‑BLBplus	out-out	none-out	N7Z	Type1	699 - 982	15	None	T790M,V948R	Epidermal growth factor receptor	Homo sapiens
TYR	EGFR	EGFR_HUMAN	6TFYB	1.7	Inactive	DFGin‑BLBplus	out-out	none-out	N7Z	Type1.5_Back	699 - 984	17	None	T790M,V948R	Epidermal growth factor receptor	Homo sapiens

Ligand: N7Z

Total number of chains: 0

Spatial label	Dihedral label	Number of Chains	Representative

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism