PDB: 9AXA — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 9AXAC
DFGin BLBplus 2 50.0% 9AXAD

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
STE MAP2K1 MP2K1_HUMAN 9AXAB 4.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 52 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXAD 4.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 59 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
TKL RAF1 RAF1_HUMAN 9AXAA 4.36 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 342 - 625 0 SEP621 Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase
TKL RAF1 RAF1_HUMAN 9AXAC 4.36 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 341 - 625 0 SEP621 Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase

PDB: 9AXA — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 9AXAC
DFGin BLBplus 2 50.0% 9AXAD

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STE MAP2K1 MP2K1_HUMAN 9AXAB 4.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 52 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXAD 4.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 59 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
TKL RAF1 RAF1_HUMAN 9AXAA 4.36 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iioo No_ligand No_ligand 342 - 625 0 SEP621 Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens
TKL RAF1 RAF1_HUMAN 9AXAC 4.36 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaioi APEdist_iioo No_ligand No_ligand 341 - 625 0 SEP621 Y340D,Y341D RAF proto-oncogene serine/threonine-protein kinase Homo sapiens

PDB: 9AXA — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism