Ligand: YW5

Total number of chains: 8
Spatial label Dihedral label Number of Chains Representative
DFGin BLBplus 8 8GK5D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 8GB4A 2.59 Inactive DFGin‑BLBplus out-out none-out ANP, YW5 Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GB4B 2.59 Inactive DFGin‑BLBplus out-out none-none ANP, YW5 Type1, Type3 700 - 1007 18 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GB4C 2.59 Inactive DFGin‑BLBplus out-out none-out ANP, YW5 Type1, Type3 700 - 1012 16 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GB4D 2.59 Inactive DFGin‑BLBplus out-out none-none ANP, YW5 Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GK5A 2.3 Inactive DFGin‑BLBplus out-out none-out Q6K, YW5 Type1, Type3 701 - 1011 17 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GK5B 2.3 Inactive DFGin‑BLBplus out-out none-none Q6K, YW5 Type1, Type3 700 - 1008 17 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GK5C 2.3 Inactive DFGin‑BLBplus out-out none-out Q6K, YW5 Type1, Type3 700 - 1008 16 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8GK5D 2.3 Inactive DFGin‑BLBplus out-out none-none Q6K, YW5 Type1, Type3 700 - 1008 15 None T790M,V948R Epidermal growth factor receptor

Ligand: YW5

Total number of chains: 8
Spatial label Dihedral label Number of Chains Representative
DFGin BLBplus 8 8GK5D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 8GB4A 2.59 Inactive DFGin‑BLBplus out-out none-out ANP, YW5 Type1, Type3 700 - 1007 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GB4B 2.59 Inactive DFGin‑BLBplus out-out none-none ANP, YW5 Type1, Type3 700 - 1007 18 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GB4C 2.59 Inactive DFGin‑BLBplus out-out none-out ANP, YW5 Type1, Type3 700 - 1012 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GB4D 2.59 Inactive DFGin‑BLBplus out-out none-none ANP, YW5 Type1, Type3 700 - 1007 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GK5A 2.3 Inactive DFGin‑BLBplus out-out none-out Q6K, YW5 Type1, Type3 701 - 1011 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GK5B 2.3 Inactive DFGin‑BLBplus out-out none-none Q6K, YW5 Type1, Type3 700 - 1008 17 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GK5C 2.3 Inactive DFGin‑BLBplus out-out none-out Q6K, YW5 Type1, Type3 700 - 1008 16 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8GK5D 2.3 Inactive DFGin‑BLBplus out-out none-none Q6K, YW5 Type1, Type3 700 - 1008 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: YW5

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism