Protein kinases in complex with Y7W (Pirtobrutinib)

Total number of genes: 1
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin BLBplus 2 8FLNA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 8FLNA 1.334 Inactive DFGin BLBplus out-out out-out Y7W BTB Type1.5_Front Allosteric
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 8FLLA 1.498 Inactive DFGin BLBplus out-none out-out Y7W BTB Type1.5_Front Allosteric

Protein kinases in complex with Y7W

Total number of genes: 1
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin BLBplus 2 8FLNA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 8FLNA 1.334 Inactive DFGin BLBplus out-out out-out Y7W BTB Type1.5_Front Allosteric
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 8FLLA 1.498 Inactive DFGin BLBplus out-none out-out Y7W BTB Type1.5_Front Allosteric

Protein kinases in complex with Y7W

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type