| PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AF-P51813-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 409 - 675 | None | None | 0 |
| 8X2AA | 1.3 | Inactive | DFGin | BLBplus | out-out | out-out | LTJ | Type1 | 411 - 671 | None | None | 3 |
| 3SXRA | 2.4 | Inactive | DFGinter | BABtrans | out-out | in-in | 1N1 | Type1 | 411 - 671 | Q432K,Q611M,D617T,Q620E | None | 0 |
| 3SXRB | 2.4 | Inactive | DFGinter | BABtrans | out-out | in-in | 1N1 | Type1 | 411 - 671 | Q432K,Q611M,D617T,Q620E | None | 0 |
| 3SXSA | 1.89 | Inactive | DFGinter | BABtrans | out-out | in-in | PP2 | Type1 | 411 - 671 | Q432K,Q611M,D617T,Q620E | None | 0 |
| 6I99A | 2.001 | Inactive | DFGinter | BABtrans | out-out | in-in | H88 | Type1 | 411 - 671 | Q432K,Q611M,D617T,Q620E | None | 0 |
| 6I99B | 2.001 | Inactive | DFGinter | BABtrans | out-out | in-in | H88 | Type1 | 411 - 671 | Q432K,Q611M,D617T,Q620E | None | 0 |
| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | AF-P51813-K1A |
| DFGin | BLBplus | 1 | 8X2AA |
| DFGinter | BABtrans | 5 | 3SXSA |
| Organism | UniprotID | PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Homo sapiens | BMX_HUMAN | AF-P51813-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 409 - 675 | None | None | 0 |
| Homo sapiens | BMX_HUMAN | 8X2AA | 1.3 | Inactive | DFGin | BLBplus | out-out | out-out | LTJ | Type1 | 411 - 671 | None | None | 3 |
| Homo sapiens | BMX_HUMAN | 3SXRA | 2.4 | Inactive | DFGinter | BABtrans | out-out | in-in | 1N1 | Type1 | 411 - 671 | Q432K,Q611M,D617T,Q620E | None | 0 |
| Homo sapiens | BMX_HUMAN | 3SXRB | 2.4 | Inactive | DFGinter | BABtrans | out-out | in-in | 1N1 | Type1 | 411 - 671 | Q432K,Q611M,D617T,Q620E | None | 0 |
| Homo sapiens | BMX_HUMAN | 3SXSA | 1.89 | Inactive | DFGinter | BABtrans | out-out | in-in | PP2 | Type1 | 411 - 671 | Q432K,Q611M,D617T,Q620E | None | 0 |
| Homo sapiens | BMX_HUMAN | 6I99A | 2.001 | Inactive | DFGinter | BABtrans | out-out | in-in | H88 | Type1 | 411 - 671 | Q432K,Q611M,D617T,Q620E | None | 0 |
| Homo sapiens | BMX_HUMAN | 6I99B | 2.001 | Inactive | DFGinter | BABtrans | out-out | in-in | H88 | Type1 | 411 - 671 | Q432K,Q611M,D617T,Q620E | None | 0 |