Ligand: TOV

Total number of chains: 4
Spatial label Dihedral label Number of Chains Representative
DFGin BLBplus 4 6WA2B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 6WA2A 2.4 Inactive DFGin‑BLBplus out-out out-out TOV Type1.5_Back 699 - 1014 12 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2B 2.4 Inactive DFGin‑BLBplus out-out out-out TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2C 2.4 Inactive DFGin‑BLBplus out-out out-none TOV Type1.5_Back 701 - 1014 12 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WA2D 2.4 Inactive DFGin‑BLBplus out-out out-out TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor

Ligand: TOV

Total number of chains: 4
Spatial label Dihedral label Number of Chains Representative
DFGin BLBplus 4 6WA2B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 6WA2A 2.4 Inactive DFGin‑BLBplus out-out out-out TOV Type1.5_Back 699 - 1014 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WA2B 2.4 Inactive DFGin‑BLBplus out-out out-out TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WA2C 2.4 Inactive DFGin‑BLBplus out-out out-none TOV Type1.5_Back 701 - 1014 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6WA2D 2.4 Inactive DFGin‑BLBplus out-out out-out TOV Type1.5_Back 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: TOV

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism