Ligand: QQM

Total number of chains: 9
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 6VH4A
DFGin BLBplus 4 6V6OD
DFGin BLBtrans 4 6V6OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 6VH4A 2.8 Active DFGin‑BLAminus in-in in-in QQM Type1 696 - 1019 3 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OC 2.1 Inactive DFGin‑BLBplus out-out out-out QQM Type1 701 - 1011 12 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OD 2.1 Inactive DFGin‑BLBplus out-out out-out QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OE 2.1 Inactive DFGin‑BLBplus out-out out-none QQM Type1 701 - 1014 11 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OH 2.1 Inactive DFGin‑BLBplus out-out out-none QQM Type1 700 - 1014 11 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OA 2.1 Inactive DFGin‑BLBtrans out-out out-out QQM Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OB 2.1 Inactive DFGin‑BLBtrans out-out out-out QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OF 2.1 Inactive DFGin‑BLBtrans out-out out-none QQM Type1 701 - 1012 13 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OG 2.1 Inactive DFGin‑BLBtrans out-out out-none QQM Type1 701 - 1009 15 None T790M,V948R Epidermal growth factor receptor

Ligand: QQM

Total number of chains: 9
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 6VH4A
DFGin BLBplus 4 6V6OD
DFGin BLBtrans 4 6V6OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 6VH4A 2.8 Active DFGin‑BLAminus in-in in-in QQM Type1 696 - 1019 3 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OC 2.1 Inactive DFGin‑BLBplus out-out out-out QQM Type1 701 - 1011 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OD 2.1 Inactive DFGin‑BLBplus out-out out-out QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OE 2.1 Inactive DFGin‑BLBplus out-out out-none QQM Type1 701 - 1014 11 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OH 2.1 Inactive DFGin‑BLBplus out-out out-none QQM Type1 700 - 1014 11 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OA 2.1 Inactive DFGin‑BLBtrans out-out out-out QQM Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OB 2.1 Inactive DFGin‑BLBtrans out-out out-out QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OF 2.1 Inactive DFGin‑BLBtrans out-out out-none QQM Type1 701 - 1012 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OG 2.1 Inactive DFGin‑BLBtrans out-out out-none QQM Type1 701 - 1009 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: QQM

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism