Ligand: QQJ

Total number of chains: 9
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 6VHNA
DFGin BLBplus 5 6V6KD
DFGin BLBtrans 3 6V6KH
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 6VHNA 2.4 None DFGin‑BLAminus in-in in-none QQJ Type1 696 - 1019 13 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KA 2.2 Inactive DFGin‑BLBplus out-out out-none QQJ Type1 700 - 1014 13 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KC 2.2 Inactive DFGin‑BLBplus out-out out-none QQJ Type1 700 - 1014 13 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KD 2.2 Inactive DFGin‑BLBplus out-out out-out QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KF 2.2 Inactive DFGin‑BLBplus out-out out-out QQJ Type1 701 - 1014 8 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KG 2.2 Inactive DFGin‑BLBplus out-out out-out QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KB 2.2 Inactive DFGin‑BLBtrans out-out out-none QQJ Type1 700 - 1014 14 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KE 2.2 Inactive DFGin‑BLBtrans out-out out-none QQJ Type1 701 - 1014 11 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6KH 2.2 Inactive DFGin‑BLBtrans out-out out-out QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor

Ligand: QQJ

Total number of chains: 9
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 6VHNA
DFGin BLBplus 5 6V6KD
DFGin BLBtrans 3 6V6KH
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 6VHNA 2.4 None DFGin‑BLAminus in-in in-none QQJ Type1 696 - 1019 13 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KA 2.2 Inactive DFGin‑BLBplus out-out out-none QQJ Type1 700 - 1014 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KC 2.2 Inactive DFGin‑BLBplus out-out out-none QQJ Type1 700 - 1014 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KD 2.2 Inactive DFGin‑BLBplus out-out out-out QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KF 2.2 Inactive DFGin‑BLBplus out-out out-out QQJ Type1 701 - 1014 8 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KG 2.2 Inactive DFGin‑BLBplus out-out out-out QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KB 2.2 Inactive DFGin‑BLBtrans out-out out-none QQJ Type1 700 - 1014 14 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KE 2.2 Inactive DFGin‑BLBtrans out-out out-none QQJ Type1 701 - 1014 11 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6KH 2.2 Inactive DFGin‑BLBtrans out-out out-out QQJ Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: QQJ

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism