Ligand: W2R

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 3W2SA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 3W2RA 2.05 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai W2R Type1.5_Back 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3W2SA 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao W2R Type1.5_Back 701 - 1019 0 None None Epidermal growth factor receptor

Ligand: W2R

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 3W2SA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 3W2RA 2.05 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai W2R Type1.5_Back 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 3W2SA 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao W2R Type1.5_Back 701 - 1019 0 None None Epidermal growth factor receptor Homo sapiens

Ligand: W2R

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism