Ligand: 8BS

Total number of chains: 11
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 5 45.5% 6Z4DB
DFGin BLBtrans 3 27.3% 6Z4DA
DFGin BLBminus 1 9.1% 7JXIC
DFGin None 1 9.1% 7JXIB
DFGout BBAminus 1 9.1% 5UGCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 7JXIC 3.0 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKA 3.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKC 3.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKE 3.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKF 3.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6Z4DB 2.0 Inactive DFGin‑BLBplus out-none none-out TYR APEdihe_niiai APEdist_aaao 8BS, 57N Type1, Type3 700 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXIA 3.0 Inactive DFGin‑BLBtrans out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS Type1 700 - 1006 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXID 3.0 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai 8BS Type1 702 - 1006 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6Z4DA 2.0 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao 8BS Type1 701 - 984 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXIB 3.0 Inactive DFGin‑None out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS Type1 702 - 1004 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5UGCA 1.58 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 8BS Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor

Ligand: 8BS

Total number of chains: 11
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 5 45.5% 6Z4DB
DFGin BLBtrans 3 27.3% 6Z4DA
DFGin BLBminus 1 9.1% 7JXIC
DFGin None 1 9.1% 7JXIB
DFGout BBAminus 1 9.1% 5UGCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 7JXIC 3.0 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS Type1 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXKA 3.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXKC 3.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXKE 3.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXKF 3.1 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS, JBJ Type1, Type3 700 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6Z4DB 2.0 Inactive DFGin‑BLBplus out-none none-out TYR APEdihe_niiai APEdist_aaao 8BS, 57N Type1, Type3 700 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXIA 3.0 Inactive DFGin‑BLBtrans out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS Type1 700 - 1006 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXID 3.0 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai 8BS Type1 702 - 1006 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6Z4DA 2.0 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao 8BS Type1 701 - 984 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7JXIB 3.0 Inactive DFGin‑None out-out none-none TYR APEdihe_nniai APEdist_aaai 8BS Type1 702 - 1004 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5UGCA 1.58 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 8BS Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens

Ligand: 8BS

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism