All / All / Type3

Total number of chains: 132
Active chains: 0
Total number of genes: 19
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 85 64.4% 8OUUB
DFGout None 21 15.9% 6NSSA
DFGin BLBplus 12 9.1% 4M13A
DFGin BLBminus 8 6.1% 7RWFA
DFGin BLAminus 3 2.3% 4ZSGA
DFGin BLAplus 2 1.5% 8A2AA
None None 1 0.8% 4F70A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC AKT2 AKT2_HUMAN 8Q61A 2.32 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn K06 Type3 1 - 435 0 None N2D RAC-beta serine/threonine-protein kinase
CMGC CDK2 CDK2_HUMAN 7RXOA 1.38 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaiii APEdist_nnoo 80E Type3 3 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7S4TA 1.91 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 88O Type3 3 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7S7AA 1.7 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaiii APEdist_nnoo 8FI Type3 2 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7S84A 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8IL Type3 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7S85A 1.98 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8IQ Type3 3 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7S9XA 1.69 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8KF Type3 3 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 7RWFA 1.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 7TW Type3 1 - 298 0 None None Cyclin-dependent kinase 2
CMGC CDK8 CDK8_HUMAN 4F6SA 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 0SQ Type3 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 4F7JA 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 0SU Type3 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 4F70A 3.0 Inactive None‑None in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 0ST Type3 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC MAPK14 MK14_HUMAN 3IW8A 2.0 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno HIZ Type3 4 - 352 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3LFBA 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z87 Type3 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3LFCA 2.8 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z86 Type3 4 - 354 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3NNVA 2.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 437 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3NNXA 2.28 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nioo EDD Type3 5 - 352 0 PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1W82A 2.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo L10 Type3 4 - 355 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1WBVA 2.0 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo LI3 Type3 4 - 355 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3HV7A 2.4 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo 1AU Type3 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2BAJA 2.25 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_iooo 1PP Type3 2 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3O8UA 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None F169Y Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3OBJA 2.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaooi APEdist_nnno BMU Type3 5 - 352 0 None F169R Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3LFDA 3.4 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z85 Type3 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1KV1A 2.5 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3O8TA 2.0 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaooi APEdist_nnno BMU Type3 5 - 352 0 None F169A Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3OC1A 2.59 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None F169G Mitogen-activated protein kinase 14
CMGC MAPK7 MK07_HUMAN 4ZSLA 2.25 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii 4QZ Type3 53 - 393 0 None None Mitogen-activated protein kinase 7
CMGC MAPK7 MK07_HUMAN 4ZSJA 2.48 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii 4R0 Type3 50 - 393 0 None None Mitogen-activated protein kinase 7
CMGC MAPK7 MK07_HUMAN 4ZSGA 1.79 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii 4QX Type3 47 - 393 0 None None Mitogen-activated protein kinase 7
OTHER ERN1 ERN1_HUMAN 4YZ9A 2.463 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno 4K7 Type3 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZ9B 2.463 Inactive DFGout‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn 4K7 Type3 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER ERN1 ERN1_HUMAN 4YZ9C 2.463 Inactive DFGout‑None out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 4K7 Type3 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1
STE MAP2K1 MP2K1_HUMAN 7MFDB 3.66 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo CHU Type3 52 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O2ZB 3.83 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo CHU Type3 52 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXAB 4.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 52 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXAD 4.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 59 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXCB 4.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 52 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9AXCD 4.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo A1AHE Type3 59 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0UD 2.91 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU Type3 31 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 9O0UF 2.91 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU Type3 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1
STE PAK1 PAK1_HUMAN 4ZJIA 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OQ Type3 254 - 542 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJIB 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OQ Type3 254 - 540 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJIC 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 4OQ Type3 250 - 541 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJID 1.99 Inactive DFGout‑BBAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oooo 4OQ Type3 253 - 541 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJJA 2.2 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OR Type3 249 - 539 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJJB 2.2 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OR Type3 251 - 539 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJJC 2.2 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno 4OR Type3 251 - 542 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJJD 2.2 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaiii APEdist_oooo 4OR Type3 252 - 541 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZLOA 2.5 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnno 4PV Type3 250 - 543 0 TPO423 None Serine/threonine-protein kinase PAK 1
TKL LIMK1 LIMK1_HUMAN 7ATUA 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 634 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7ATUB 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 636 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7ATUC 2.8 Inactive DFGout‑BBAminus out-none out-none nonTYR APEdihe_aanai APEdist_nnnn RXN Type3 350 - 632 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7ATUD 2.8 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaini APEdist_nnno RXN Type3 354 - 632 0 None None LIM domain kinase 1
TKL LIMK2 LIMK2_HUMAN 4TPTA 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iooi 35H Type3 330 - 631 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 4TPTB 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iooi 35H Type3 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 5NXDB 1.9 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 9D8 Type3 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 5NXDA 1.9 Inactive DFGout‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 9D8 Type3 330 - 632 0 None None LIM domain kinase 2
TKL RIPK1 RIPK1_HUMAN 9MZYA 2.32 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1BU6 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZYB 2.32 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno A1BU6 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZZB 2.68 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1BU5 Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZXA 2.53 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU4 Type3 6 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZXB 2.53 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU4 Type3 6 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C3EA 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno EJY Type3 9 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITHA 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno RCM Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITHB 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITIA 2.86 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo 1HW Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITIB 2.86 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 1HW Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6NYHA 2.1 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno L8D Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6NYHB 2.1 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno L8D Type3 11 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q31A 2.05 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1CNU Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32A 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 6 - 293 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32B 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1CNV Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32C 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 6 - 293 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32D 2.49 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7FCZA 2.21 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 3IF Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7FCZB 2.21 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3IF Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY8A 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IX7 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY8B 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 1HX Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY9A 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IX9 Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY9B 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1IX9 Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C4DA 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C4DB 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C4DC 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 10 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C4DD 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno EJP Type3 5 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 5HX6A 2.23 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 65U Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 5TX5A 2.56 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 7MJ Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6HHOA 3.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno G4W Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6HHOB 3.49 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn G4W Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6OCQB 2.793 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn M5J Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6R5FA 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn JSW Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6R5FB 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6R5FC 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6R5FD 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 11 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6RLNA 2.87 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno K8K Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6NW2A 2.0 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn L4Y Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6NW2B 2.0 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno L4Y Type3 11 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTYA 2.145 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TYR ABL1 ABL1_HUMAN 3QRKA 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 9DP Type3 229 - 496 0 None None Tyrosine-protein kinase ABL1
TYR DDR1 DDR1_HUMAN 7FEHA 1.61 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 3UI Type3 603 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5BVKA 2.29 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 4VC Type3 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR EGFR EGFR_HUMAN 8A27A 1.07 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 701 - 985 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A2AA 1.43 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 700 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A2DA 1.11 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nniai APEdist_aaai KXY Type3 701 - 1021 0 None L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5ZWJA 2.9 Inactive DFGin‑BLBplus out-none none-out TYR APEdihe_nniai APEdist_aaao 9LL Type3 702 - 985 0 None T790M,C797S,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8A2BA 1.69 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 702 - 990 0 None L858R,V948R Epidermal growth factor receptor
TYR ITK ITK_HUMAN 4M12A 2.15 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 1YZ Type3 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 4M13A 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 1E0 Type3 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK
TYR MERTK MERTK_HUMAN 7AW4A 1.98 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S5E Type3 576 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AW4B 1.98 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S5E Type3 574 - 862 0 None None Tyrosine-protein kinase Mer
TYR MET MET_HUMAN 8OUUA 1.77 Inactive DFGout‑BBAminus out-out out-in TYR APEdihe_iiiai APEdist_aaai W49 Type3 1059 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUUB 1.77 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W49 Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUVA 1.783 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3R Type3 1053 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUVB 1.783 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3R Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OV7A 1.95 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iioai APEdist_aaao W3W Type3 1051 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OVZA 2.206 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3N Type3 1061 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OVZB 2.206 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3N Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OWGA 2.631 Inactive DFGout‑BBAminus out-none out-none TYR APEdihe_nnnai APEdist_aaan W40 Type3 1060 - 1344 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OWGB 2.631 Inactive DFGout‑BBAminus out-none out-in TYR APEdihe_iiiai APEdist_aaai W40 Type3 1060 - 1343 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OWGC 2.631 Inactive DFGout‑BBAminus out-none none-out TYR APEdihe_nniai APEdist_aaao W40 Type3 1060 - 1343 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OW3A 2.27 Inactive DFGout‑BBAminus out-none none-none TYR APEdihe_nniai APEdist_aaai W40 Type3 1058 - 1345 0 None None Hepatocyte growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PL4A 2.06 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai OO7 Type3 485 - 795 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6NSPA 2.31 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai L0P Type3 500 - 795 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6NPTA 2.19 Inactive DFGout‑None out-out out-in TYR APEdihe_iiiai APEdist_aaai KWY Type3 491 - 795 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6NSSA 1.97 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai L0M Type3 485 - 795 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6D1YA 1.93 Inactive DFGout‑None out-out out-in TYR APEdihe_iiiai APEdist_aaai FQJ Type3 481 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMIA 1.87 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 6UE Type3 486 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMJA 2.04 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 6UF Type3 486 - 795 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMKA 2.24 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 6UG Type3 484 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMMA 2.12 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 6UJ Type3 484 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMLA 2.01 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 6UH Type3 474 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5KMNA 2.14 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 6UK Type3 474 - 796 0 None None High affinity nerve growth factor receptor
TYR PTK2 FAK1_HUMAN 4I4FA 1.75 Inactive DFGout‑None out-out none-out TYR APEdihe_niiai APEdist_aaao 1BR Type3 415 - 686 0 None None Focal adhesion kinase 1

All / All / Type3

Total number of chains: 149
Active chains: 0
Total number of genes: 20
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 92 61.7% 8OUUB
DFGout None 21 14.1% 6NSSA
DFGin BLBminus 18 12.1% 5R97A
DFGin BLBplus 12 8.1% 4M13A
DFGin BLAminus 3 2.0% 4ZSGA
DFGin BLAplus 2 1.3% 8A2AA
None None 1 0.7% 4F70A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR SRC SRC_CHICK 3F3UB 2.5 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_nniai APEdist_aaai 1AW Type3 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
AGC AKT2 AKT2_HUMAN 8Q61A 2.32 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn K06 Type3 1 - 435 0 None N2D RAC-beta serine/threonine-protein kinase Homo sapiens
CMGC CDK2 CDK2_HUMAN 7RXOA 1.38 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaiii APEdist_nnoo 80E Type3 3 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7S4TA 1.91 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 88O Type3 3 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7S7AA 1.7 Inactive DFGin‑BLBminus out-none out-out nonTYR APEdihe_aaiii APEdist_nnoo 8FI Type3 2 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7S84A 2.0 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8IL Type3 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7S85A 1.98 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8IQ Type3 3 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7S9XA 1.69 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnoo 8KF Type3 3 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK2 CDK2_HUMAN 7RWFA 1.5 Inactive DFGin‑BLBminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 7TW Type3 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
CMGC CDK8 CDK8_HUMAN 4F6SA 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 0SQ Type3 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 4F7JA 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 0SU Type3 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 4F70A 3.0 Inactive None‑None in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 0ST Type3 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3IW8A 2.0 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno HIZ Type3 4 - 352 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3LFBA 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z87 Type3 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3LFCA 2.8 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z86 Type3 4 - 354 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3NNVA 2.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 437 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3NNXA 2.28 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nioo EDD Type3 5 - 352 0 PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1W82A 2.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo L10 Type3 4 - 355 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1WBVA 2.0 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo LI3 Type3 4 - 355 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HV7A 2.4 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo 1AU Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2BAJA 2.25 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_iooo 1PP Type3 2 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3O8UA 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None F169Y Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3OBJA 2.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaooi APEdist_nnno BMU Type3 5 - 352 0 None F169R Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3LFDA 3.4 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z85 Type3 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1KV1A 2.5 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3O8TA 2.0 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaooi APEdist_nnno BMU Type3 5 - 352 0 None F169A Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3OC1A 2.59 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None F169G Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK7 MK07_HUMAN 4ZSLA 2.25 Inactive DFGin‑BLAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oiii 4QZ Type3 53 - 393 0 None None Mitogen-activated protein kinase 7 Homo sapiens
CMGC MAPK7 MK07_HUMAN 4ZSJA 2.48 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii 4R0 Type3 50 - 393 0 None None Mitogen-activated protein kinase 7 Homo sapiens
CMGC MAPK7 MK07_HUMAN 4ZSGA 1.79 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii 4QX Type3 47 - 393 0 None None Mitogen-activated protein kinase 7 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZ9A 2.463 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaooi APEdist_nnno 4K7 Type3 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZ9B 2.463 Inactive DFGout‑None out-out none-none nonTYR APEdihe_aannn APEdist_nnnn 4K7 Type3 563 - 963 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
OTHER ERN1 ERN1_HUMAN 4YZ9C 2.463 Inactive DFGout‑None out-out none-none nonTYR APEdihe_aanii APEdist_nnnn 4K7 Type3 562 - 964 0 None None Serine/threonine-protein kinase/endoribonuclease IRE1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 7MFDB 3.66 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo CHU Type3 52 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9O2ZB 3.83 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo CHU Type3 52 - 383 0 None None Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXAB 4.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 52 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXAD 4.36 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 59 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXCB 4.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaooo APEdist_oooo A1AHE Type3 52 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9AXCD 4.16 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo A1AHE Type3 59 - 383 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9O0UD 2.91 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU Type3 31 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 9O0UF 2.91 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aaoio APEdist_oooo CHU Type3 30 - 380 0 None S218A,S222A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJIA 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OQ Type3 254 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJIB 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OQ Type3 254 - 540 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJIC 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 4OQ Type3 250 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJID 1.99 Inactive DFGout‑BBAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oooo 4OQ Type3 253 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJJA 2.2 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OR Type3 249 - 539 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJJB 2.2 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OR Type3 251 - 539 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJJC 2.2 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno 4OR Type3 251 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJJD 2.2 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaiii APEdist_oooo 4OR Type3 252 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZLOA 2.5 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaioo APEdist_nnno 4PV Type3 250 - 543 0 TPO423 None Serine/threonine-protein kinase PAK 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATUA 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 634 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATUB 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 636 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATUC 2.8 Inactive DFGout‑BBAminus out-none out-none nonTYR APEdihe_aanai APEdist_nnnn RXN Type3 350 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATUD 2.8 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaini APEdist_nnno RXN Type3 354 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 4TPTA 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iooi 35H Type3 330 - 631 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 4TPTB 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iooi 35H Type3 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 5NXDB 1.9 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 9D8 Type3 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 5NXDA 1.9 Inactive DFGout‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 9D8 Type3 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZYA 2.32 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1BU6 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZYB 2.32 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno A1BU6 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZZB 2.68 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1BU5 Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZXA 2.53 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU4 Type3 6 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZXB 2.53 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU4 Type3 6 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C3EA 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno EJY Type3 9 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITHA 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno RCM Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITHB 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITIA 2.86 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo 1HW Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITIB 2.86 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 1HW Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6NYHA 2.1 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno L8D Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6NYHB 2.1 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno L8D Type3 11 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q31A 2.05 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1CNU Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q32A 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 6 - 293 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q32B 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1CNV Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q32C 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 6 - 293 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q32D 2.49 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7FCZA 2.21 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 3IF Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7FCZB 2.21 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3IF Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY8A 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IX7 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY8B 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 1HX Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY9A 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IX9 Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY9B 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1IX9 Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C4DA 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C4DB 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C4DC 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 10 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C4DD 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno EJP Type3 5 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 5HX6A 2.23 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 65U Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 5TX5A 2.56 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 7MJ Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6HHOA 3.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno G4W Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6HHOB 3.49 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn G4W Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6OCQB 2.793 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn M5J Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6R5FA 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn JSW Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6R5FB 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6R5FC 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6R5FD 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 11 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6RLNA 2.87 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno K8K Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6NW2A 2.0 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn L4Y Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6NW2B 2.0 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno L4Y Type3 11 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9GTYA 2.145 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TYR ABL1 ABL1_HUMAN 3QRKA 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 9DP Type3 229 - 496 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR DDR1 DDR1_HUMAN 7FEHA 1.61 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 3UI Type3 603 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5BVKA 2.29 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 4VC Type3 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR EGFR EGFR_HUMAN 8A27A 1.07 Inactive DFGin‑BLAplus out-out none-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 701 - 985 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8A2AA 1.43 Inactive DFGin‑BLAplus out-out out-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 700 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8A2DA 1.11 Inactive DFGin‑BLBminus out-out none-none TYR APEdihe_nniai APEdist_aaai KXY Type3 701 - 1021 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5ZWJA 2.9 Inactive DFGin‑BLBplus out-none none-out TYR APEdihe_nniai APEdist_aaao 9LL Type3 702 - 985 0 None T790M,C797S,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8A2BA 1.69 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_nniai APEdist_aaao KY9 Type3 702 - 990 0 None L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR ITK ITK_HUMAN 4M12A 2.15 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 1YZ Type3 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR ITK ITK_HUMAN 4M13A 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 1E0 Type3 355 - 618 0 None None Tyrosine-protein kinase ITK/TSK Homo sapiens
TYR MERTK MERTK_HUMAN 7AW4A 1.98 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S5E Type3 576 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7AW4B 1.98 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S5E Type3 574 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MET MET_HUMAN 8OUUA 1.77 Inactive DFGout‑BBAminus out-out out-in TYR APEdihe_iiiai APEdist_aaai W49 Type3 1059 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OUUB 1.77 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W49 Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OUVA 1.783 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3R Type3 1053 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OUVB 1.783 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3R Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OV7A 1.95 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iioai APEdist_aaao W3W Type3 1051 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OVZA 2.206 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3N Type3 1061 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OVZB 2.206 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3N Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OWGA 2.631 Inactive DFGout‑BBAminus out-none out-none TYR APEdihe_nnnai APEdist_aaan W40 Type3 1060 - 1344 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OWGB 2.631 Inactive DFGout‑BBAminus out-none out-in TYR APEdihe_iiiai APEdist_aaai W40 Type3 1060 - 1343 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OWGC 2.631 Inactive DFGout‑BBAminus out-none none-out TYR APEdihe_nniai APEdist_aaao W40 Type3 1060 - 1343 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OW3A 2.27 Inactive DFGout‑BBAminus out-none none-none TYR APEdihe_nniai APEdist_aaai W40 Type3 1058 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6PL4A 2.06 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai OO7 Type3 485 - 795 0 SEP677 None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6NSPA 2.31 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai L0P Type3 500 - 795 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6NPTA 2.19 Inactive DFGout‑None out-out out-in TYR APEdihe_iiiai APEdist_aaai KWY Type3 491 - 795 0 SEP677 None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6NSSA 1.97 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai L0M Type3 485 - 795 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6D1YA 1.93 Inactive DFGout‑None out-out out-in TYR APEdihe_iiiai APEdist_aaai FQJ Type3 481 - 796 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5KMIA 1.87 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 6UE Type3 486 - 796 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5KMJA 2.04 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 6UF Type3 486 - 795 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5KMKA 2.24 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 6UG Type3 484 - 796 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5KMMA 2.12 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 6UJ Type3 484 - 796 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5KMLA 2.01 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 6UH Type3 474 - 796 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5KMNA 2.14 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai 6UK Type3 474 - 796 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR PTK2 FAK1_HUMAN 4I4FA 1.75 Inactive DFGout‑None out-out none-out TYR APEdihe_niiai APEdist_aaao 1BR Type3 415 - 686 0 None None Focal adhesion kinase 1 Homo sapiens
CMGC MAPK14 MK14_MOUSE 5R8YA 1.679 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SMV Type3 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8ZA 1.65 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SN4 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R97A 1.438 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo RUY Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9DA 1.69 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo N9J Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9EA 1.775 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo S7S Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9KA 1.498 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SR4 Type3 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9QA 1.645 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo LVD Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9WA 1.89 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo STV Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA1A 1.61 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo PO6 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA9A 1.68 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SWD Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P5KA 2.09 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P5K Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P78A 2.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P78 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P79A 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P79 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P7AA 2.31 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P7A Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P7BA 1.9 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P7B Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P7CA 2.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno P7C Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus

All / All / Type3

Total number of chains: 17
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 10 58.8% 5R97A
DFGout BBAminus 7 41.2% 3P7BA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR SRC SRC_CHICK 3F3UB 2.5 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_nniai APEdist_aaai 1AW Type3 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
CMGC MAPK14 MK14_MOUSE 5R8YA 1.679 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SMV Type3 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R8ZA 1.65 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SN4 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R97A 1.438 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo RUY Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9DA 1.69 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo N9J Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9EA 1.775 Inactive DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo S7S Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9KA 1.498 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SR4 Type3 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9QA 1.645 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo LVD Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5R9WA 1.89 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo STV Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA1A 1.61 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo PO6 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 5RA9A 1.68 Inactive DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo SWD Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P5KA 2.09 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P5K Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P78A 2.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P78 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P79A 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P79 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P7AA 2.31 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P7A Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P7BA 1.9 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P7B Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P7CA 2.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno P7C Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus