Protein kinases in complex with CHU (Avutometinib)

Total number of genes: 1
Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLBplus 12 3WIGA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0UB 2.91 Inactive DFGin BLBplus out-out out-out CHU Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0UH 2.91 Inactive DFGin BLBplus out-out out-out CHU ANP Type1 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0VB 3.5 Inactive DFGin BLBplus out-out out-out CHU ANP Type1 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0VH 3.5 Inactive DFGin BLBplus out-out out-out CHU ANP Type1 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3WIGA 2.7 Inactive DFGin BLBplus out-out out-out ANP CHU Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0ZB 3.12 Inactive DFGin BLBplus out-out out-out ANP CHU Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7MFDB 3.66 Inactive DFGin BLBplus out-out out-out CHU Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O2ZB 3.83 Inactive DFGin BLBplus out-out out-out CHU Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0UD 2.91 Inactive DFGin BLBplus out-out out-out CHU Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0UF 2.91 Inactive DFGin BLBplus out-out out-out CHU Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0VD 3.5 Inactive DFGin BLBplus out-out out-out CHU ANP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0VF 3.5 Inactive DFGin BLBplus out-out out-out CHU ANP Type3 Type1

Protein kinases in complex with CHU

Total number of genes: 1
Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLBplus 12 3WIGA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0UB 2.91 Inactive DFGin BLBplus out-out out-out CHU Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0UH 2.91 Inactive DFGin BLBplus out-out out-out CHU ANP Type1 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0VB 3.5 Inactive DFGin BLBplus out-out out-out CHU ANP Type1 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0VH 3.5 Inactive DFGin BLBplus out-out out-out CHU ANP Type1 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3WIGA 2.7 Inactive DFGin BLBplus out-out out-out ANP CHU Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0ZB 3.12 Inactive DFGin BLBplus out-out out-out ANP CHU Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7MFDB 3.66 Inactive DFGin BLBplus out-out out-out CHU Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O2ZB 3.83 Inactive DFGin BLBplus out-out out-out CHU Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0UD 2.91 Inactive DFGin BLBplus out-out out-out CHU Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0UF 2.91 Inactive DFGin BLBplus out-out out-out CHU Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0VD 3.5 Inactive DFGin BLBplus out-out out-out CHU ANP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 9O0VF 3.5 Inactive DFGin BLBplus out-out out-out CHU ANP Type3 Type1

Protein kinases in complex with CHU

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type