| PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AF-P09769-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 255 - 522 | None | None | 0 |
| 7UY0A | 2.55 | Inactive | DFGin | BLBplus | out-out | out-in | VSE | Type1.5_Back | 80 - 527 | Q524E,P525E,G526I,D527P | X523 | 0 |
| 7UY0B | 2.55 | Inactive | DFGin | BLBplus | out-out | out-out | VSE | Type1.5_Back | 80 - 527 | Q524E,P525E,G526I,D527P | X523 | 0 |
| 7UY3A | 2.99 | Inactive | DFGout | None | in-in | out-in | OJL | Type2 | 135 - 527 | Q524E,P525E,G526I,D527P | X523 | 2 |
| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | AF-P09769-K1A |
| DFGin | BLBplus | 2 | 7UY0A |
| DFGout | None | 1 | 7UY3A |
| Organism | UniprotID | PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Homo sapiens | FGR_HUMAN | AF-P09769-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 255 - 522 | None | None | 0 |
| Homo sapiens | FGR_HUMAN | 7UY0A | 2.55 | Inactive | DFGin | BLBplus | out-out | out-in | VSE | Type1.5_Back | 80 - 527 | Q524E,P525E,G526I,D527P | X523 | 0 |
| Homo sapiens | FGR_HUMAN | 7UY0B | 2.55 | Inactive | DFGin | BLBplus | out-out | out-out | VSE | Type1.5_Back | 80 - 527 | Q524E,P525E,G526I,D527P | X523 | 0 |
| Homo sapiens | FGR_HUMAN | 7UY3A | 2.99 | Inactive | DFGout | None | in-in | out-in | OJL | Type2 | 135 - 527 | Q524E,P525E,G526I,D527P | X523 | 2 |