TEK (Angiopoietin-1 receptor)

Group: TYR
Uniprot: TIE2_HUMAN
Domain boundary: 824 - 1094


Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q02763-K1A
DFGin BLBplus 1 3L8PA
DFGinter BABtrans 2 1FVRB
DFGout BBAminus 5 6MWEA
DFGout None 3 2WQBA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q02763-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 816 - 1102 None None 0
3L8PA 2.4 Inactive DFGin BLBplus out-out out-none 0CE Type1 814 - 1121 None None 5
1FVRA 2.2 Inactive DFGinter BABtrans out-out out-out No_ligand No_ligand 813 - 1121 None None 4
1FVRB 2.2 Inactive DFGinter BABtrans out-out out-out No_ligand No_ligand 813 - 1121 None None 3
2OO8X 2.2 Inactive DFGout BBAminus in-out none-out RAJ Type2 836 - 1117 None None 11
2OSCA 2.8 Inactive DFGout BBAminus in-in none-out MUH Type2 837 - 1116 None None 11
2P4IA 2.5 Inactive DFGout BBAminus in-in out-in MR9 Type2 838 - 1117 None None 5
6MWEA 2.05 Inactive DFGout BBAminus in-in out-out 919 Type2 816 - 1122 None None 2
6MWEB 2.05 Inactive DFGout BBAminus in-in out-out 919 Type2 816 - 1122 None None 3
2WQBA 2.95 Inactive DFGout None none-none out-out QQ1 Type1 816 - 1120 D964N None 1
2P4IB 2.5 Inactive DFGout None in-in none-out MR9 Type2 836 - 1117 None None 12
4X3JA 2.5 Inactive DFGout None in-out none-out 3WR Type2 838 - 1117 D964N None 15

TEK (Angiopoietin-1 receptor)

Group: TYR
Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q02763-K1A
DFGin BLBplus 1 3L8PA
DFGinter BABtrans 2 1FVRB
DFGout BBAminus 5 6MWEA
DFGout None 3 2WQBA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens TIE2_HUMAN AF-Q02763-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 816 - 1102 None None 0
Homo sapiens TIE2_HUMAN 3L8PA 2.4 Inactive DFGin BLBplus out-out out-none 0CE Type1 814 - 1121 None None 5
Homo sapiens TIE2_HUMAN 1FVRA 2.2 Inactive DFGinter BABtrans out-out out-out No_ligand No_ligand 813 - 1121 None None 4
Homo sapiens TIE2_HUMAN 1FVRB 2.2 Inactive DFGinter BABtrans out-out out-out No_ligand No_ligand 813 - 1121 None None 3
Homo sapiens TIE2_HUMAN 2OO8X 2.2 Inactive DFGout BBAminus in-out none-out RAJ Type2 836 - 1117 None None 11
Homo sapiens TIE2_HUMAN 2OSCA 2.8 Inactive DFGout BBAminus in-in none-out MUH Type2 837 - 1116 None None 11
Homo sapiens TIE2_HUMAN 2P4IA 2.5 Inactive DFGout BBAminus in-in out-in MR9 Type2 838 - 1117 None None 5
Homo sapiens TIE2_HUMAN 6MWEA 2.05 Inactive DFGout BBAminus in-in out-out 919 Type2 816 - 1122 None None 2
Homo sapiens TIE2_HUMAN 6MWEB 2.05 Inactive DFGout BBAminus in-in out-out 919 Type2 816 - 1122 None None 3
Homo sapiens TIE2_HUMAN 2WQBA 2.95 Inactive DFGout None none-none out-out QQ1 Type1 816 - 1120 D964N None 1
Homo sapiens TIE2_HUMAN 2P4IB 2.5 Inactive DFGout None in-in none-out MR9 Type2 836 - 1117 None None 12
Homo sapiens TIE2_HUMAN 4X3JA 2.5 Inactive DFGout None in-out none-out 3WR Type2 838 - 1117 D964N None 15

TEK (Angiopoietin-1 receptor)

No non-human structures known.