TYR_TEK (Angiopoietin-1 receptor)

Total number of chains: 13
Active chains: 2
Uniprot: TIE2_HUMAN
Kinase Domain Residues: 824 - 1094
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 5 38.5% 6MWEA
DFGout None 3 23.1% 2WQBA
DFGin BLAminus 2 15.4% AF-Q02763-K1A
DFGinter BABtrans 2 15.4% 1FVRB
DFGin BLBplus 1 7.7% 3L8PA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q02763-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 816 - 1102 0 None None Angiopoietin-1 receptor
AF-Q02763-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 816 - 1102 0 None None Angiopoietin-1 receptor
3L8PA 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan 0CE Type1 814 - 1121 0 None None Angiopoietin-1 receptor
1FVRA 2.2 Inactive DFGinter‑BABtrans out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 813 - 1121 0 None None Angiopoietin-1 receptor
1FVRB 2.2 Inactive DFGinter‑BABtrans out-out out-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 813 - 1121 0 None None Angiopoietin-1 receptor
2OO8X 2.2 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_iiiai APEdist_aaao RAJ Type2 836 - 1117 0 None None Angiopoietin-1 receptor
2OSCA 2.8 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao MUH Type2 837 - 1116 0 None None Angiopoietin-1 receptor
2P4IA 2.5 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai MR9 Type2 838 - 1117 0 None None Angiopoietin-1 receptor
6MWEA 2.05 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oooai APEdist_aaao 919 Type2 816 - 1122 0 None None Angiopoietin-1 receptor
6MWEB 2.05 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oooai APEdist_aaao 919 Type2 816 - 1122 0 None None Angiopoietin-1 receptor
2WQBA 2.95 Inactive DFGout‑None none-none out-out TYR APEdihe_iiiai APEdist_aaao QQ1 Type1 816 - 1120 0 None D964N Angiopoietin-1 receptor
2P4IB 2.5 Inactive DFGout‑None in-in none-out TYR APEdihe_iiiai APEdist_aaao MR9 Type2 836 - 1117 0 None None Angiopoietin-1 receptor
4X3JA 2.5 Inactive DFGout‑None in-out none-out TYR APEdihe_nniai APEdist_aaao 3WR Type2 838 - 1117 0 None D964N Angiopoietin-1 receptor

TYR_TEK (Angiopoietin-1 receptor)

Total number of chains: 13
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 5 38.5% 6MWEA
DFGout None 3 23.1% 2WQBA
DFGin BLAminus 2 15.4% AF-Q02763-K1A
DFGinter BABtrans 2 15.4% 1FVRB
DFGin BLBplus 1 7.7% 3L8PA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TIE2_HUMAN AF-Q02763-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 816 - 1102 0 None None Angiopoietin-1 receptor Homo sapiens
TIE2_HUMAN AF-Q02763-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 816 - 1102 0 None None Angiopoietin-1 receptor Homo sapiens
TIE2_HUMAN 3L8PA 2.4 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nnnai APEdist_aaan 0CE Type1 814 - 1121 0 None None Angiopoietin-1 receptor Homo sapiens
TIE2_HUMAN 1FVRA 2.2 Inactive DFGinter‑BABtrans out-out out-out TYR APEdihe_nniai APEdist_aaao No_ligand No_ligand 813 - 1121 0 None None Angiopoietin-1 receptor Homo sapiens
TIE2_HUMAN 1FVRB 2.2 Inactive DFGinter‑BABtrans out-out out-out TYR APEdihe_niiai APEdist_aaao No_ligand No_ligand 813 - 1121 0 None None Angiopoietin-1 receptor Homo sapiens
TIE2_HUMAN 2OO8X 2.2 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_iiiai APEdist_aaao RAJ Type2 836 - 1117 0 None None Angiopoietin-1 receptor Homo sapiens
TIE2_HUMAN 2OSCA 2.8 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao MUH Type2 837 - 1116 0 None None Angiopoietin-1 receptor Homo sapiens
TIE2_HUMAN 2P4IA 2.5 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai MR9 Type2 838 - 1117 0 None None Angiopoietin-1 receptor Homo sapiens
TIE2_HUMAN 6MWEA 2.05 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oooai APEdist_aaao 919 Type2 816 - 1122 0 None None Angiopoietin-1 receptor Homo sapiens
TIE2_HUMAN 6MWEB 2.05 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oooai APEdist_aaao 919 Type2 816 - 1122 0 None None Angiopoietin-1 receptor Homo sapiens
TIE2_HUMAN 2WQBA 2.95 Inactive DFGout‑None none-none out-out TYR APEdihe_iiiai APEdist_aaao QQ1 Type1 816 - 1120 0 None D964N Angiopoietin-1 receptor Homo sapiens
TIE2_HUMAN 2P4IB 2.5 Inactive DFGout‑None in-in none-out TYR APEdihe_iiiai APEdist_aaao MR9 Type2 836 - 1117 0 None None Angiopoietin-1 receptor Homo sapiens
TIE2_HUMAN 4X3JA 2.5 Inactive DFGout‑None in-out none-out TYR APEdihe_nniai APEdist_aaao 3WR Type2 838 - 1117 0 None D964N Angiopoietin-1 receptor Homo sapiens

TYR_TEK (Angiopoietin-1 receptor)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism