PDB: 8TO3 — TYR EGFR_HUMAN

Total number of chains: 4
Spatial label Dihedral label Number of Chains Representative
DFGin BLBplus 2 8TO3A
DFGin BLBtrans 2 8TO3D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 8TO3B 2.49 Inactive DFGin‑BLBplus out-out out-out ANP Type1 702 - 1014 13 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3A 2.49 Inactive DFGin‑BLBplus out-out out-out IXC Type1.5_Front 702 - 1007 15 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3C 2.49 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 702 - 1014 13 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8TO3D 2.49 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 702 - 1008 13 None T790M,V948R Epidermal growth factor receptor

PDB: 8TO3 — TYR EGFR_HUMAN

Total number of chains: 4
Spatial label Dihedral label Number of Chains Representative
DFGin BLBplus 2 8TO3A
DFGin BLBtrans 2 8TO3D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 8TO3B 2.49 Inactive DFGin‑BLBplus out-out out-out ANP Type1 702 - 1014 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO3A 2.49 Inactive DFGin‑BLBplus out-out out-out IXC Type1.5_Front 702 - 1007 15 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO3C 2.49 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 702 - 1014 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8TO3D 2.49 Inactive DFGin‑BLBtrans out-out out-out ANP Type1 702 - 1008 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens

PDB: 8TO3 — TYR EGFR_HUMAN

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism