STE_PAK2 (Serine/threonine-protein kinase PAK 2)

Total number of chains: 10
Active chains: 2
Uniprot: PAK2_HUMAN
Kinase Domain Residues: 249 - 499
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 30.0% AF-Q13177-K1A
DFGin BLAplus 3 30.0% 9LBGA
DFGin BLBplus 2 20.0% 9D51B
DFGout BBAminus 1 10.0% 9M41A
DFGout None 1 10.0% 9M41B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q13177-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 241 - 507 0 None None Serine/threonine-protein kinase PAK 2
AF-Q13177-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 241 - 507 0 None None Serine/threonine-protein kinase PAK 2
9D51A 2.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A2Q Type1 230 - 523 0 None D368N,T402E,P498Q,M514A Serine/threonine-protein kinase PAK 2
9LBGB 2.89 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aanoo APEdist_nnnn MLT Allosteric 91 - 522 0 None K278R Serine/threonine-protein kinase PAK 2
9LBGA 2.89 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaioo APEdist_nnoo No_ligand No_ligand 84 - 522 0 None K278R Serine/threonine-protein kinase PAK 2
9LBFA 2.62 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiio APEdist_nnoo No_ligand No_ligand 86 - 522 0 None D368N Serine/threonine-protein kinase PAK 2
9LBFB 2.62 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 93 - 522 0 None D368N Serine/threonine-protein kinase PAK 2
9D51B 2.1 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1A2Q Type1 231 - 522 0 None D368N,T402E,P498Q,M514A Serine/threonine-protein kinase PAK 2
9M41A 3.02 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 85 - 520 0 None K278R,D368N Serine/threonine-protein kinase PAK 2
9M41B 3.02 Inactive DFGout‑None out-none out-out nonTYR APEdihe_aaiio APEdist_nnno No_ligand No_ligand 83 - 521 0 None K278R,D368N Serine/threonine-protein kinase PAK 2

STE_PAK2 (Serine/threonine-protein kinase PAK 2)

Total number of chains: 10
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 30.0% AF-Q13177-K1A
DFGin BLAplus 3 30.0% 9LBGA
DFGin BLBplus 2 20.0% 9D51B
DFGout BBAminus 1 10.0% 9M41A
DFGout None 1 10.0% 9M41B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
PAK2_HUMAN AF-Q13177-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 241 - 507 0 None None Serine/threonine-protein kinase PAK 2 Homo sapiens
PAK2_HUMAN AF-Q13177-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 241 - 507 0 None None Serine/threonine-protein kinase PAK 2 Homo sapiens
PAK2_HUMAN 9D51A 2.1 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii A1A2Q Type1 230 - 523 0 None D368N,T402E,P498Q,M514A Serine/threonine-protein kinase PAK 2 Homo sapiens
PAK2_HUMAN 9LBGB 2.89 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aanoo APEdist_nnnn MLT Allosteric 91 - 522 0 None K278R Serine/threonine-protein kinase PAK 2 Homo sapiens
PAK2_HUMAN 9LBGA 2.89 Inactive DFGin‑BLAplus out-none out-out nonTYR APEdihe_aaioo APEdist_nnoo No_ligand No_ligand 84 - 522 0 None K278R Serine/threonine-protein kinase PAK 2 Homo sapiens
PAK2_HUMAN 9LBFA 2.62 Inactive DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaiio APEdist_nnoo No_ligand No_ligand 86 - 522 0 None D368N Serine/threonine-protein kinase PAK 2 Homo sapiens
PAK2_HUMAN 9LBFB 2.62 Inactive DFGin‑BLBplus out-out out-out nonTYR APEdihe_aanio APEdist_nnnn No_ligand No_ligand 93 - 522 0 None D368N Serine/threonine-protein kinase PAK 2 Homo sapiens
PAK2_HUMAN 9D51B 2.1 Inactive DFGin‑BLBplus out-out none-out nonTYR APEdihe_aaiio APEdist_oooo A1A2Q Type1 231 - 522 0 None D368N,T402E,P498Q,M514A Serine/threonine-protein kinase PAK 2 Homo sapiens
PAK2_HUMAN 9M41A 3.02 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 85 - 520 0 None K278R,D368N Serine/threonine-protein kinase PAK 2 Homo sapiens
PAK2_HUMAN 9M41B 3.02 Inactive DFGout‑None out-none out-out nonTYR APEdihe_aaiio APEdist_nnno No_ligand No_ligand 83 - 521 0 None K278R,D368N Serine/threonine-protein kinase PAK 2 Homo sapiens

STE_PAK2 (Serine/threonine-protein kinase PAK 2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism