PAK2 (Serine/threonine-protein kinase PAK 2)

Group: STE

Uniprot: PAK2_HUMAN

Domain boundary: 249 - 499

Total number of chains: 9

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	2	AF-Q13177-K1A
DFGin	BLAplus	3	9LBGA
DFGin	BLBplus	2	9D51B
DFGout	BBAminus	1	9M41A
DFGout	None	1	9M41B

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
AF-Q13177-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	241 - 507	None	None	0
9D51A	2.1	Inactive	DFGin	BLAminus	in-out	in-in	A1A2Q	Type1	230 - 523	D368N,T402E,P498Q,M514A	None	5
9LBGB	2.89	Inactive	DFGin	BLAplus	out-none	out-none	MLT	Allosteric	91 - 522	K278R	None	10
9LBGA	2.89	Inactive	DFGin	BLAplus	out-none	out-out	No_ligand	No_ligand	84 - 522	K278R	None	7
9LBFA	2.62	Inactive	DFGin	BLAplus	out-out	out-out	No_ligand	No_ligand	86 - 522	D368N	None	8
9LBFB	2.62	Inactive	DFGin	BLBplus	out-out	out-none	No_ligand	No_ligand	93 - 522	D368N	None	14
9D51B	2.1	Inactive	DFGin	BLBplus	out-out	none-out	A1A2Q	Type1	231 - 522	D368N,T402E,P498Q,M514A	None	4
9M41A	3.02	Inactive	DFGout	BBAminus	out-none	out-out	No_ligand	No_ligand	85 - 520	K278R,D368N	None	4
9M41B	3.02	Inactive	DFGout	None	out-none	out-out	No_ligand	No_ligand	83 - 521	K278R,D368N	None	7

PAK2 (Serine/threonine-protein kinase PAK 2)

Group: STE

Total number of chains: 9

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	2	AF-Q13177-K1A
DFGin	BLAplus	3	9LBGA
DFGin	BLBplus	2	9D51B
DFGout	BBAminus	1	9M41A
DFGout	None	1	9M41B

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	PAK2_HUMAN	AF-Q13177-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	241 - 507	None	None	0
Homo sapiens	PAK2_HUMAN	9D51A	2.1	Inactive	DFGin	BLAminus	in-out	in-in	A1A2Q	Type1	230 - 523	D368N,T402E,P498Q,M514A	None	5
Homo sapiens	PAK2_HUMAN	9LBGB	2.89	Inactive	DFGin	BLAplus	out-none	out-none	MLT	Allosteric	91 - 522	K278R	None	10
Homo sapiens	PAK2_HUMAN	9LBGA	2.89	Inactive	DFGin	BLAplus	out-none	out-out	No_ligand	No_ligand	84 - 522	K278R	None	7
Homo sapiens	PAK2_HUMAN	9LBFA	2.62	Inactive	DFGin	BLAplus	out-out	out-out	No_ligand	No_ligand	86 - 522	D368N	None	8
Homo sapiens	PAK2_HUMAN	9LBFB	2.62	Inactive	DFGin	BLBplus	out-out	out-none	No_ligand	No_ligand	93 - 522	D368N	None	14
Homo sapiens	PAK2_HUMAN	9D51B	2.1	Inactive	DFGin	BLBplus	out-out	none-out	A1A2Q	Type1	231 - 522	D368N,T402E,P498Q,M514A	None	4
Homo sapiens	PAK2_HUMAN	9M41A	3.02	Inactive	DFGout	BBAminus	out-none	out-out	No_ligand	No_ligand	85 - 520	K278R,D368N	None	4
Homo sapiens	PAK2_HUMAN	9M41B	3.02	Inactive	DFGout	None	out-none	out-out	No_ligand	No_ligand	83 - 521	K278R,D368N	None	7

PAK2 (Serine/threonine-protein kinase PAK 2)

No non-human structures known.