KinCore

Ligand: N78

Total number of chains: 2

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLBplus	2	6TG0B

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein
TYR	EGFR	EGFR_HUMAN	6TG0A	1.5	Inactive	DFGin‑BLBplus	out-out	none-none	N78	Type1.5_Back	700 - 985	18	None	T790M,V948R	Epidermal growth factor receptor
TYR	EGFR	EGFR_HUMAN	6TG0B	1.5	Inactive	DFGin‑BLBplus	out-out	out-none	N78	Type1.5_Back	698 - 984	11	None	T790M,V948R	Epidermal growth factor receptor

Ligand: N78

Total number of chains: 2

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLBplus	2	6TG0B

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism
TYR	EGFR	EGFR_HUMAN	6TG0A	1.5	Inactive	DFGin‑BLBplus	out-out	none-none	N78	Type1.5_Back	700 - 985	18	None	T790M,V948R	Epidermal growth factor receptor	Homo sapiens
TYR	EGFR	EGFR_HUMAN	6TG0B	1.5	Inactive	DFGin‑BLBplus	out-out	out-none	N78	Type1.5_Back	698 - 984	11	None	T790M,V948R	Epidermal growth factor receptor	Homo sapiens

Ligand: N78

Total number of chains: 0

Spatial label	Dihedral label	Number of Chains	Representative

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism