9D51

PAK2 (Serine/threonine-protein kinase PAK 2)
Group: STE
Uniprot: PAK2_HUMAN
Organism: Homo sapiens
Domain boundary: 249 - 499
Resolu: 2.1

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in A1A2Q Type1 230 - 523 5
B Inactive DFGin BLBplus out-out none-out A1A2Q Type1 231 - 522 4
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       237        247        257        267 
tdeEIMEKLR TIVSIGDPKK KYTRYEKIGQ GASGTVFTAT 
       277        287        297        307 
DVALGQEVAI KQINLQKQPK KELIINEILV MKELKNPNIV 
       317        327        337        347 
NFLDSYLVGD ELFVVMEYLA GGSLTDVVTE TCMDEAQIAA 
       357        367        377        387 
VCRECLQALE FLHANQVIHR NIKSDNVLLG MEGSVKLTDF 
       397        407        417        427 
GFCaqitPEQ SKRSEMVGTP YWMAPEVVTR KAYGPKVDIW 
       437        447        457        467 
SLGIMAIEMV EGEPPYLNEN PLRALYLIAT NGTPELQNPE 
       477        487        497        507 
KLSPIFRDFL NRCLEMDVEK RGSAKELLQH QFLKLAKPLS 
       517 
SLTPLIAAAK EAMKSnr
Lower-case residues are disordered in structure.
Mutations: D368N,T402E,P498Q,M514A
Phosphorylation: None