Ligand: 5WE

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 6X3OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR BTK BTK_HUMAN 6X3NA 1.95 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai ULV, 5WE Type1, Allosteric 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5FBOA 1.894 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_oiiai APEdist_aaao 5WH, 5WE Type1.5_Back, Allosteric 392 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5FBNC 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 5WF, 5WE Type1.5_Front, Allosteric 395 - 658 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6X3OA 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ULY, 5WE Type1.5_Front, Allosteric 395 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6X3OB 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ULY, 5WE Type1.5_Front, Allosteric 393 - 659 0 None None Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 5FBND 1.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 5WF, 5WE, 5WE, 5WE Type1.5_Front, Allosteric, Allosteric, Allosteric 394 - 658 0 None None Tyrosine-protein kinase BTK

Ligand: 5WE

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 6X3OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR BTK BTK_HUMAN 6X3NA 1.95 Inactive DFGin‑BLBplus out-out none-none TYR APEdihe_niiai APEdist_aaai ULV, 5WE Type1, Allosteric 392 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5FBOA 1.894 Inactive DFGin‑BLBplus out-out none-out TYR APEdihe_oiiai APEdist_aaao 5WH, 5WE Type1.5_Back, Allosteric 392 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5FBNC 1.8 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao 5WF, 5WE Type1.5_Front, Allosteric 395 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6X3OA 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ULY, 5WE Type1.5_Front, Allosteric 395 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 6X3OB 1.9 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao ULY, 5WE Type1.5_Front, Allosteric 393 - 659 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR BTK BTK_HUMAN 5FBND 1.8 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_nniai APEdist_aaai 5WF, 5WE, 5WE, 5WE Type1.5_Front, Allosteric, Allosteric, Allosteric 394 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens

Ligand: 5WE

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism