PDB: 5X2A — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 5X2AB
DFGin BLBplus 1 25.0% 5X2AD

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 5X2AD 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AC 1.85 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao 7XO Type1 700 - 1015 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AB 1.85 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_oiiai APEdist_aaai 7XO, ANP Type1, ATPlike 700 - 1022 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AA 1.85 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai 7XO, ANP Type1, Allosteric 700 - 1011 0 None T790M,V948R Epidermal growth factor receptor

PDB: 5X2A — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 5X2AB
DFGin BLBplus 1 25.0% 5X2AD

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 5X2AD 1.85 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_niiai APEdist_aaao ANP ATPlike 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2AC 1.85 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao 7XO Type1 700 - 1015 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2AB 1.85 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_oiiai APEdist_aaai 7XO, ANP Type1, ATPlike 700 - 1022 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2AA 1.85 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai 7XO, ANP Type1, Allosteric 700 - 1011 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

PDB: 5X2A — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism