MAPK3 (Mitogen-activated protein kinase 3)

Group: CMGC
Uniprot: MK03_HUMAN
Domain boundary: 42 - 330


Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 7 AF-P27361-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-P27361-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 34 - 338 None None 0
6GESB 2.07 Active DFGin BLAminus in-in in-in 6H3 Type1 25 - 374 None None 0
2ZOQA 2.39 Active DFGin BLAminus in-in in-in 5ID Type1 24 - 375 None X204 0
2ZOQB 2.39 Inactive DFGin BLAminus in-out in-in 5ID Type1 24 - 375 None X204 0
6GESA 2.07 Active DFGin BLAminus in-in in-in 6H3 EWH Type1 Allosteric 25 - 374 None None 0
4QTBA 1.4 Active DFGin BLAminus in-in in-in 38Z Type1.5_Front 24 - 374 None None 0
4QTBB 1.4 Active DFGin BLAminus in-in in-in 38Z Type1.5_Front 27 - 374 None None 0

MAPK3 (Mitogen-activated protein kinase 3)

Group: CMGC
Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 7 AF-P27361-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens MK03_HUMAN AF-P27361-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 34 - 338 None None 0
Homo sapiens MK03_HUMAN 6GESB 2.07 Active DFGin BLAminus in-in in-in 6H3 Type1 25 - 374 None None 0
Homo sapiens MK03_HUMAN 2ZOQA 2.39 Active DFGin BLAminus in-in in-in 5ID Type1 24 - 375 None X204 0
Homo sapiens MK03_HUMAN 2ZOQB 2.39 Inactive DFGin BLAminus in-out in-in 5ID Type1 24 - 375 None X204 0
Homo sapiens MK03_HUMAN 6GESA 2.07 Active DFGin BLAminus in-in in-in 6H3 EWH Type1 Allosteric 25 - 374 None None 0
Homo sapiens MK03_HUMAN 4QTBA 1.4 Active DFGin BLAminus in-in in-in 38Z Type1.5_Front 24 - 374 None None 0
Homo sapiens MK03_HUMAN 4QTBB 1.4 Active DFGin BLAminus in-in in-in 38Z Type1.5_Front 27 - 374 None None 0

MAPK3 (Mitogen-activated protein kinase 3)

No non-human structures known.