CMGC_MAPK3 (Mitogen-activated protein kinase 3)

Total number of chains: 8
Active chains: 2
Uniprot: MK03_HUMAN
Kinase Domain Residues: 42 - 330
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% AF-P27361-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P27361-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 34 - 338 0 None None Mitogen-activated protein kinase 3
AF-P27361-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 34 - 338 0 None None Mitogen-activated protein kinase 3
6GESB 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6H3 Type1 25 - 374 0 None None Mitogen-activated protein kinase 3
2ZOQA 2.39 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 5ID Type1 24 - 375 0 PTR204 None Mitogen-activated protein kinase 3
2ZOQB 2.39 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiii 5ID Type1 24 - 375 0 PTR204 None Mitogen-activated protein kinase 3
6GESA 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6H3, EWH Type1, Allosteric 25 - 374 0 None None Mitogen-activated protein kinase 3
4QTBA 1.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 38Z Type1.5_Front 24 - 374 0 None None Mitogen-activated protein kinase 3
4QTBB 1.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 38Z Type1.5_Front 27 - 374 0 None None Mitogen-activated protein kinase 3

CMGC_MAPK3 (Mitogen-activated protein kinase 3)

Total number of chains: 8
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% AF-P27361-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MK03_HUMAN AF-P27361-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 34 - 338 0 None None Mitogen-activated protein kinase 3 Homo sapiens
MK03_HUMAN AF-P27361-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 34 - 338 0 None None Mitogen-activated protein kinase 3 Homo sapiens
MK03_HUMAN 6GESB 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6H3 Type1 25 - 374 0 None None Mitogen-activated protein kinase 3 Homo sapiens
MK03_HUMAN 2ZOQA 2.39 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 5ID Type1 24 - 375 0 PTR204 None Mitogen-activated protein kinase 3 Homo sapiens
MK03_HUMAN 2ZOQB 2.39 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiii 5ID Type1 24 - 375 0 PTR204 None Mitogen-activated protein kinase 3 Homo sapiens
MK03_HUMAN 6GESA 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6H3, EWH Type1, Allosteric 25 - 374 0 None None Mitogen-activated protein kinase 3 Homo sapiens
MK03_HUMAN 4QTBA 1.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 38Z Type1.5_Front 24 - 374 0 None None Mitogen-activated protein kinase 3 Homo sapiens
MK03_HUMAN 4QTBB 1.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 38Z Type1.5_Front 27 - 374 0 None None Mitogen-activated protein kinase 3 Homo sapiens

CMGC_MAPK3 (Mitogen-activated protein kinase 3)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism