PDB: 5X2A — TYR EGFR_HUMAN

Total number of chains: 4
Spatial label Dihedral label Number of Chains Representative
DFGin BLBplus 1 5X2AD
DFGin BLBtrans 3 5X2AB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 5X2AD 1.85 Inactive DFGin‑BLBplus out-out out-out ANP Type1 701 - 1014 10 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AC 1.85 Inactive DFGin‑BLBtrans out-out out-out 7XO Type1 700 - 1015 13 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AA 1.85 Inactive DFGin‑BLBtrans out-out out-none 7XO, ANP Type1, Allosteric 700 - 1011 13 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2AB 1.85 Inactive DFGin‑BLBtrans out-out out-out 7XO, ANP Type1, Type1 700 - 1022 0 None T790M,V948R Epidermal growth factor receptor

PDB: 5X2A — TYR EGFR_HUMAN

Total number of chains: 4
Spatial label Dihedral label Number of Chains Representative
DFGin BLBplus 1 5X2AD
DFGin BLBtrans 3 5X2AB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 5X2AD 1.85 Inactive DFGin‑BLBplus out-out out-out ANP Type1 701 - 1014 10 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2AC 1.85 Inactive DFGin‑BLBtrans out-out out-out 7XO Type1 700 - 1015 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2AA 1.85 Inactive DFGin‑BLBtrans out-out out-none 7XO, ANP Type1, Allosteric 700 - 1011 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2AB 1.85 Inactive DFGin‑BLBtrans out-out out-out 7XO, ANP Type1, Type1 700 - 1022 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

PDB: 5X2A — TYR EGFR_HUMAN

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism