Ligand

Protein kinases in complex with 7XO

Total number of genes: 1

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	5X26A
DFGin	BLBtrans	3	5X2AB

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X26A	2.951	Active	DFGin	BLAminus	in-in	in-in	7XO	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X2AC	1.85	Inactive	DFGin	BLBtrans	out-out	out-out	7XO	Type1
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X2AA	1.85	Inactive	DFGin	BLBtrans	out-out	out-in	7XO ANP	Type1 Allosteric
TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X2AB	1.85	Inactive	DFGin	BLBtrans	out-out	out-in	7XO ANP	Type1 Type1

Protein kinases in complex with 7XO

Total number of genes: 1

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	5X26A
DFGin	BLBtrans	3	5X2AB

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X26A	2.951	Active	DFGin	BLAminus	in-in	in-in	7XO	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X2AC	1.85	Inactive	DFGin	BLBtrans	out-out	out-out	7XO	Type1
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X2AA	1.85	Inactive	DFGin	BLBtrans	out-out	out-in	7XO ANP	Type1 Allosteric
Homo sapiens	TYR	EGFR	EGFR_HUMAN	Epidermal growth factor receptor	5X2AB	1.85	Inactive	DFGin	BLBtrans	out-out	out-in	7XO ANP	Type1 Type1

Protein kinases in complex with 7XO

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type