Human protein kinases in complex with Allosteric ligands

Total number of genes: 57
Total number of chains: 511
Spatial Label Dihedral Label AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Total
DFGin BLAminus 31 78 1 136 0 0 2 85 20 5 358
DFGin BLAplus 0 0 0 0 0 0 0 0 2 0 2
DFGin ABAminus 6 7 0 7 0 0 0 0 8 2 30
DFGin BLBminus 0 1 0 10 0 0 0 0 1 1 13
DFGin BLBplus 0 0 0 7 0 0 1 0 12 0 20
DFGin BLBtrans 0 0 0 4 0 0 0 0 1 0 5
DFGin None 2 6 0 11 0 0 0 0 0 0 19
DFGinter BABtrans 0 0 0 0 0 0 0 0 0 0 0
DFGinter None 1 0 0 2 0 0 0 0 2 0 5
DFGout BBAminus 4 0 0 4 0 0 0 1 18 0 27
DFGout None 1 0 0 7 0 0 1 0 3 0 12
None None 6 1 0 12 0 0 1 0 0 0 20
Total - 51 93 1 200 0 0 5 86 67 8 511
Download as tsv
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment


Group Gene UniprotID Protein PDB Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActloopCT Ligand Type
AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 3O96A Inactive DFGout BBAminus none-none out-none IQO Allosteric
AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6HHHA Inactive DFGout BBAminus none-none out-out G4Q Allosteric
AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6HHJA Inactive DFGout BBAminus out-out out-out G4H Allosteric
AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6S9WA Inactive DFGout BBAminus out-out out-out L1Z Allosteric
AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 5KCVA Inactive DFGout None none-none none-none 6S1 Allosteric
AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6HHFA Inactive None None none-none out-none G4K Allosteric
AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6HHGA Inactive None None none-none out-out G4T Allosteric
AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6HHIA Inactive None None none-none out-out G4N Allosteric
AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6S9XA Inactive None None none-none out-out L1W Allosteric
AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 7NH4A Inactive None None none-none out-out UCE Allosteric
AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 7NH5A Inactive None None none-none out-out UC8 Allosteric
AGC CDC42BPB MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta 3TKUA Active DFGin BLAminus in-in in-in M77 M77 Type1 Allosteric
AGC CDC42BPB MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta 3TKUB Active DFGin BLAminus in-in in-in M77 M77 Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXA Active DFGin BLAminus in-in in-in 1F8 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXB Active DFGin BLAminus in-in in-in 1F8 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXC Active DFGin BLAminus in-in in-in 1F8 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXD Active DFGin BLAminus in-in in-in 1F8 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXE Active DFGin BLAminus in-in in-in 1F8 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXF None DFGin BLAminus in-none in-in 1F8 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXG Active DFGin BLAminus in-in in-in 1F8 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXH Active DFGin BLAminus in-in in-in 1F8 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 8DQTA Active DFGin BLAminus in-in in-in U35 U35 U35 Allosteric Allosteric Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZA Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZB Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZC Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZD Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3OTUA Active DFGin BLAminus in-in in-in J30 BI4 Allosteric Type1.5_Front
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3HRFA Active DFGin BLAminus in-in in-in ATP P47 Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4A06A Active DFGin BLAminus in-in in-in ATP A06 Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4AW0A Active DFGin BLAminus in-in in-in ATP MJF Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4AW1A Active DFGin BLAminus in-in in-in ATP 21O Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4RQKA Active DFGin BLAminus in-in in-in ATP R1S Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4RQVA Active DFGin BLAminus in-in in-in ATP R2S Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVOA Active DFGin BLAminus in-in in-in ATP 78W Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4CT1A None DFGin BLAminus in-none in-in ATP 31S Type1 Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4XX9A Active DFGin BLAminus in-in in-in ATP RF4 RF4 Type1 Allosteric Allosteric
AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4A07A Active DFGin BLAminus in-in in-in ATP AZ7 AZ7 Type1 Allosteric Allosteric
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 5IZJA Inactive DFGin BLAminus in-out in-in 6J9 Allosteric
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 5IZJB Inactive DFGin BLAminus out-out in-in 6J9 Allosteric
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 5J5XA Active DFGin BLAminus in-in in-in 6J9 Allosteric
AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4UA Inactive DFGin ABAminus in-in in-in EX6 Allosteric
AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4UB Inactive DFGin ABAminus in-in in-in EX6 Allosteric
AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4WA Inactive DFGin ABAminus in-in in-in EZJ Allosteric
AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4WB Inactive DFGin ABAminus in-in in-in EZJ Allosteric
AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4TA Inactive DFGin ABAminus in-in in-in PCG ATP Allosteric Type1
AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4TB Inactive DFGin ABAminus in-in in-in PCG ATP Allosteric Type1
AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4VA Inactive DFGin BLAminus in-in in-out EXZ Allosteric
AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4VB Active DFGin BLAminus in-in in-in EXZ Allosteric
AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G77A Inactive DFGin None none-none out-in ANP ANP Allosteric Type1
AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G77B Inactive DFGin None none-none out-in ANP ANP Allosteric Type1
AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G76A Inactive DFGinter None none-none out-in ANP ANP Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DPVA Inactive DFGin ABAminus out-in in-out 5DN SKE Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DR6A Inactive DFGin ABAminus out-in in-out 5E1 SKE Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DN3A Inactive DFGin BLAminus in-in in-out 5DN ATP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1EA Inactive DFGin BLAminus in-in in-out T0X ATP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DT4A Inactive DFGin BLAminus in-in in-out 5DN ATP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1MA Inactive DFGin BLAminus in-in in-out T4X ADP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8SSPA Inactive DFGin BLAminus out-out in-in PDO 627 Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DOSA Inactive DFGin BLAminus in-in in-out 5DN ATP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DR2A Inactive DFGin BLAminus in-in in-out 5E1 ATP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1DA Inactive DFGin BLAminus in-in in-out T2F ADP T5L Allosteric Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1GA Inactive DFGin BLAminus in-in in-out T3I ADP T5L Allosteric Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1HA Inactive DFGin BLAminus in-in in-out T3U ADP T5L Allosteric Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1KA Inactive DFGin BLAminus in-in in-out T4O ADP T5L Allosteric Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6VPLA Inactive DFGin BLAminus out-out in-out ANP R7D Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6VPLB Inactive DFGin BLAminus out-out in-out ANP R7D Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6VPMA Inactive DFGin BLAminus out-out in-out AMP R74 Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6VPMB Inactive DFGin BLAminus out-out in-out AMP R74 Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DR9A Inactive DFGin BLAminus out-out out-out SKE 5E2 Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORLA Inactive DFGin BLAminus in-in in-out ADP A4W Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORNA Inactive DFGin BLAminus in-in in-out ADP A5E Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OROA Inactive DFGin BLAminus in-in in-out ADP A5H Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORPA Inactive DFGin BLAminus in-in in-out ADP A5K Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORRA Inactive DFGin BLAminus in-in in-out ADP A5Q Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORSA Inactive DFGin BLAminus in-in in-out ADP A5W Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORTA Inactive DFGin BLAminus in-in in-out ADP A5Z Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORVA Inactive DFGin BLAminus in-in in-out ADP A65 Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORWA Inactive DFGin BLAminus in-in in-out ADP A6E Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORXA Inactive DFGin BLAminus in-in in-out ADP A6H Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORYA Inactive DFGin BLAminus in-in in-out ADP AY4 Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORZA Inactive DFGin BLAminus in-in in-out ADP A6W Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS0A Inactive DFGin BLAminus in-in in-out ADP A6Z Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS1A Inactive DFGin BLAminus in-in in-out ADP A7H Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS2A Inactive DFGin BLAminus in-in in-out ADP A7K Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS3A Inactive DFGin BLAminus in-in in-out ADP A7N Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS4A Inactive DFGin BLAminus in-in in-out ADP A8H Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS6A Inactive DFGin BLAminus in-in in-out ADP A7Q Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OSEA Inactive DFGin BLAminus in-in in-out ADP A98 Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OSFA Inactive DFGin BLAminus in-in in-out ADP A9E Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OSDA Inactive DFGin BLAminus in-in in-out ADP A9B Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS5A Inactive DFGin BLAminus in-in in-out ADP A8K Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6R49A Inactive DFGin BLAminus in-in in-out ADP JSB Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4AA Inactive DFGin BLAminus in-in in-out ADP JRT Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4BA Inactive DFGin BLAminus in-in in-out ADP JSN Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4CA Inactive DFGin BLAminus in-in in-out ADP JRQ Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4DA Inactive DFGin BLAminus in-in in-out ADP JRW Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 7ZTLA Active DFGin BLAminus in-in in-in ADP BCN Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8OF5A Inactive DFGin BLAminus in-in in-out ADP MPO Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C14A Inactive DFGin BLAminus in-in in-out ADP T5L T0L Type1 Allosteric Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C15A Inactive DFGin BLAminus in-in in-out ADP T4C T5L Type1 Allosteric Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1FA Inactive DFGin BLAminus in-in in-out ADP T5L T2O Type1 Allosteric Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1IA Inactive DFGin BLAminus in-in in-out ADP T1L T5L Type1 Allosteric Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OBJA Inactive DFGin None out-out in-out ATP 9QK Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OBRA Inactive None None out-out out-out 9QT SKE Allosteric Type1
CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 3JVRA Active DFGin BLAminus in-in in-in AGX Allosteric
CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 3JVSA Inactive DFGin BLAminus in-out in-in AGY Allosteric
CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 3F9NA Active DFGin BLAminus in-in in-in 38M Allosteric
CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 5F4NA Active DFGin BLAminus in-in in-in 5UY 5UY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CA None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CB None DFGin BLAminus in-out in-none PDY PDY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CC None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CD None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CE None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CF None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CG None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CH None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CI None DFGin BLAminus in-out in-none PDY PDY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CJ None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CK None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CL None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 6T8XA Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 6T8XB None DFGin BLAminus in-in in-none B97 MW8 Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 6T8XC None DFGin BLAminus in-in in-none B97 MW8 Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 6T8XD Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 6T8XE Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 6T8XF Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric
CAMK PIM1 PIM1_HUMAN Serine/threonine-protein kinase pim-1 4I41A Inactive DFGin ABAminus in-in in-in MIX MIX Type1 Allosteric
CAMK PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 6C9FA Inactive DFGin ABAminus out-out in-in R34 STU Allosteric Type1
CAMK PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 6C9GA Inactive DFGin BLAminus out-out in-in R93 STU Allosteric Type1
CAMK PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 6C9HA Inactive DFGin BLAminus out-out in-in R34 STU Allosteric Type1
CAMK PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 6C9JA Active DFGin BLAminus out-in in-in R34 STU Allosteric Type1
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 5ISOA Inactive DFGin ABAminus out-none in-in STU 992 Type1 Allosteric
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 5ISOC Inactive DFGin ABAminus out-none in-in STU 992 Type1 Allosteric
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 6B1UC Inactive DFGin ABAminus out-out in-in STU CG7 Type1 Allosteric
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 6B2EA None DFGin BLAminus out-none in-out STU CG7 Type1 Allosteric
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 4CFEA Inactive DFGin BLAminus out-out in-in STU 992 Type1 Allosteric
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 4CFEC Inactive DFGin BLAminus out-out in-in STU 992 Type1 Allosteric
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 7MYJA Inactive DFGin BLBminus out-in in-in 4O7 ZQV Type1 Allosteric
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 5EZVA Inactive DFGin None in-in in-in STU C1V Type1 Allosteric
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 5EZVC Inactive DFGin None out-in in-in STU C1V Type1 Allosteric
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 4ZHXC Inactive DFGin None out-out in-out 4O7 C1V Type1 Allosteric
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 6B1UA Inactive DFGin None out-in in-in STU CG7 Type1 Allosteric
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 4CFFC Inactive DFGin None out-out in-in STU C1V Type1 Allosteric
CAMK RPS6KA5 KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 7UP6A None DFGin BLAminus in-in in-none SUU OXM OXM Type1 Allosteric Allosteric
CK1 CSNK1G1 KC1G1_HUMAN Casein kinase I isoform gamma-1 2CMWA Active DFGin BLAminus in-in in-in OLP OLP OLP Type1 Allosteric Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8VQ3A Active DFGin BLAminus in-in in-in A1AC4 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8VQ4A Active DFGin BLAminus in-in in-in A1AC5 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXFA Inactive DFGin BLBminus out-out out-out 2AN 2AN Allosteric Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXZA Inactive DFGin BLBminus out-out out-out 2AN 2AN JWS Allosteric Type3 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4D1ZA Inactive DFGin BLBminus out-none none-none WG8 WG8 Type1 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5FP5A Inactive DFGin BLBminus out-none none-none 1Y6 1Y6 Type1 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5FP6A Inactive DFGin BLBminus out-out none-out MFZ MFZ Type1 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXQA Inactive DFGin BLBminus out-out out-out 2AN 2AN 2AN Type1 Allosteric Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PY1A Inactive DFGin BLBminus out-out out-out SU9 2AN 2AN Type1 Allosteric Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EZ7A Inactive DFGin BLBminus out-out out-out STU 2AN 2AN Type1 Type3 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7UG1A Inactive DFGin BLBminus out-out out-out N5R N5R Type3 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4FKUA Inactive DFGin BLBplus out-out out-out 60K 60K Allosteric Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5OO0A Inactive DFGin BLBtrans out-out out-out 9YZ Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5OSJA Inactive DFGin BLBtrans out-out out-out AAK Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6Q4KA Inactive DFGin BLBtrans out-out out-out HHW HHW Allosteric Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6Q4DA Inactive DFGin BLBtrans out-out out-out HHT HHT HHT HHT HHT HHT Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3EZRA Inactive DFGin None out-out none-none EZR EZR Type1 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5A14A Inactive DFGout None in-in out-out LQ5 LQ5 Type2 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6Q3FA Inactive None None out-out out-out HEW Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6Q49A Inactive None None out-out out-out HGQ Allosteric
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 6TPAA Inactive DFGout BBAminus out-out out-none NZ8 NZ5 NZ5 NZ5 Type2 Allosteric Allosteric Allosteric
CMGC CLK1 CLK1_HUMAN Dual specificity protein kinase CLK1 5J1WC Inactive DFGin BLAminus in-in in-out 6FB 6FB Type1 Allosteric
CMGC CLK1 CLK1_HUMAN Dual specificity protein kinase CLK1 6YTGA Active DFGin BLAminus in-in in-in KHC KHC Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CT0A Active DFGin BLAminus in-in in-in 54P Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CT0B Active DFGin BLAminus in-in in-in 54P Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CTPA Active DFGin BLAminus in-in in-in 54R Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CTPB Active DFGin BLAminus in-in in-in 54R Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MMFA Active DFGin BLAminus in-in in-in JMB Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MMRB Active DFGin BLAminus in-in in-in H83 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MO6A Active DFGin BLAminus in-in in-in KXZ Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MO7A Active DFGin BLAminus in-in in-in YRA Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MODA Active DFGin BLAminus in-in in-in 86L Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OT5A Active DFGin BLAminus in-in in-in AWK Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OT5B Active DFGin BLAminus in-in in-in AWK Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OT6A Active DFGin BLAminus in-in in-in AJK Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTDA Active DFGin BLAminus in-in in-in AOW Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTDB Active DFGin BLAminus in-in in-in AOW Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTHA Active DFGin BLAminus in-in in-in AQ8 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTHB Active DFGin BLAminus in-in in-in AQ8 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTLA Active DFGin BLAminus in-in in-in AQT Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTLB Active DFGin BLAminus in-in in-in AQT Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTOA Active DFGin BLAminus in-in in-in AQW Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTOB Active DFGin BLAminus in-in in-in AQW Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OUEB Active DFGin BLAminus in-in in-in AVZ Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OUMA Active DFGin BLAminus in-in in-in AVK Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OUUA Active DFGin BLAminus in-in in-in AWN Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OUUB Active DFGin BLAminus in-in in-in AWN Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6EIIA Active DFGin BLAminus in-in in-in B5W Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6EIIB Active DFGin BLAminus in-in in-in B5W Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY5A Active DFGin BLAminus in-in in-in 1NP Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6GIHA Active DFGin BLAminus in-in in-in EZN Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSUA Active DFGin BLAminus in-in in-in AFW Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 3W8LB Active DFGin BLAminus in-in in-in IHP IHP Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CX9B Active DFGin BLAminus in-in in-in 551 551 Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MMRA Active DFGin BLAminus in-in in-in H83 H83 Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORHA Active DFGin BLAminus in-in in-in A4N A4N Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORHB Active DFGin BLAminus in-in in-in A4N A4N Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTQA Active DFGin BLAminus in-in in-in AUH AUH Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTZA Active DFGin BLAminus in-in in-in AUT AUT Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OYFA Active DFGin BLAminus in-in in-in B4Q B4Q Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CX9A Active DFGin BLAminus in-in in-in 551 551 551 Allosteric Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSZA Active DFGin BLAminus in-in in-in AHK AHK AHK Allosteric Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTSA Active DFGin BLAminus in-in in-in AU2 AU2 AU2 Allosteric Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6EHUA Active DFGin BLAminus in-in in-in B5E B5E B5E Allosteric Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6EHUB Active DFGin BLAminus in-in in-in B5E B5E B5E Allosteric Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CS6A Active DFGin BLAminus in-in in-in K82 K82 K82 K82 Allosteric Allosteric Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OULA Active DFGin BLAminus in-in in-in AWE AWE AWE AWE AWE AWE Allosteric Allosteric Allosteric Allosteric Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CU2A Active DFGin BLAminus in-in in-in 551 551 551 54G Allosteric Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OS8A Active DFGin BLAminus in-in in-in J27 J27 J27 ATP Allosteric Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTRA Active DFGin BLAminus in-in in-in AU8 AU8 AU8 ATP Allosteric Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CSHA Active DFGin BLAminus in-in in-in 54E 54E ATP Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CSHB Active DFGin BLAminus in-in in-in 54E 54E ATP Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CU0A Active DFGin BLAminus in-in in-in 54R 54R 54G Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CU0B Active DFGin BLAminus in-in in-in 54R 54R 54G Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CU2B Active DFGin BLAminus in-in in-in 551 551 54G Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OS7A Active DFGin BLAminus in-in in-in A8Q A8Q ATP Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6GMDB Active DFGin BLAminus in-in in-in A8Q A8Q ATP Allosteric Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OS7B Active DFGin BLAminus in-in in-in A8Q ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6GMDA Active DFGin BLAminus in-in in-in A8Q ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY5B Active DFGin BLAminus in-in in-in 1NP 1NP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY8B Active DFGin BLAminus in-in in-in KE0 KE0 Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CVFA Active DFGin BLAminus in-in in-in 54Z ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6FVFA Active DFGin BLAminus in-in in-in 503 ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6FVGA Active DFGin BLAminus in-in in-in E8K ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY0A Active DFGin BLAminus in-in in-in KC0 ADP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AE7A Active DFGin BLAminus in-in in-in LVU ADP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AEKA Active DFGin BLAminus in-in in-in LVL ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AEMA Active DFGin BLAminus in-in in-in LVF ATP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6YPNB Active DFGin BLAminus in-in in-in ADP ADP Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5NQCA Active DFGin BLAminus in-in in-in 1KP 1KP Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 3H30A Active DFGin BLAminus in-in in-in RFZ RFZ Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7X4HA Active DFGin BLAminus in-in in-in 8BH 8BH Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7AT5A Active DFGin BLAminus in-in in-in RXE 42J Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7AT5B Active DFGin BLAminus in-in in-in RXE 42J Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CVHA Active DFGin BLAminus in-in in-in ADP IHP Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CVHB Active DFGin BLAminus in-in in-in ADP IHP Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MP8A Active DFGin BLAminus in-in in-in ADP RKN Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MP8B Active DFGin BLAminus in-in in-in ADP RKN Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORJB Active DFGin BLAminus in-in in-in ADP A4Q Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORKA Active DFGin BLAminus in-in in-in ADP A4T Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OUEA Active DFGin BLAminus in-in in-in AW5 AVZ Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6TLLA Active DFGin BLAminus in-in in-in TBS TBS Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6TLOA Active DFGin BLAminus in-in in-in NKB NKB Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6TLSA Active DFGin BLAminus in-in in-in NL2 NL2 Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6TLUAAA Active DFGin BLAminus in-in in-in NKT NKT Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6TLVA Active DFGin BLAminus in-in in-in NKW NKW Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7QGBA Active DFGin BLAminus in-in in-in 7M0 7M0 Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7QGDA Active DFGin BLAminus in-in in-in 7M0 7M0 Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MOTA Active DFGin BLAminus in-in in-in HBD HBD Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYDA Active DFGin BLAminus in-in in-in ATP KD6 Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYKA Active DFGin BLAminus in-in in-in ADP KEC Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYRA Active DFGin BLAminus in-in in-in ATP KF6 Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AECA Active DFGin BLAminus in-in in-in ATP LW3 Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSPA Active DFGin BLAminus in-in in-in ATP A9W Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSRA Active DFGin BLAminus in-in in-in ATP AFK Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MPJA Active DFGin BLAminus in-in in-in ADP IHP J2P Type1 Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OQUA Active DFGin BLAminus in-in in-in ADP A4B IHP Type1 Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY2A Active DFGin BLAminus in-in in-in ATP H4N H4N Type1 Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYOA Active DFGin BLAminus in-in in-in ATP KEX KEX Type1 Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSLA Active DFGin BLAminus in-in in-in ADP A9K A9K Type1 Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MOEB Active DFGin BLAminus in-in in-in ADP IHP OQC OQC Type1 Allosteric Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORJA Active DFGin BLAminus in-in in-in ADP A4Q A4Q IHP Type1 Allosteric Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CLPB Active DFGin BLAminus in-in in-in 42J 42J 42J 42J 42J Type1 Allosteric Allosteric Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MOEA Active DFGin BLAminus in-in in-in ADP IHP OQC OQC OQC Type1 Allosteric Allosteric Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CLPA Active DFGin BLAminus in-in in-in 42J 42J 42J 42J 42J 42J Type1 Type1 Allosteric Allosteric Allosteric Allosteric
CMGC CSNK2A2 CSK22_HUMAN Casein kinase II subunit alpha' 8Q77A Active DFGin BLAminus in-in in-in LN3 LN3 Allosteric Type1
CMGC CSNK2A2 CSK22_HUMAN Casein kinase II subunit alpha' 8QBUA Active DFGin BLAminus in-in in-in 42J 3NG Allosteric Type1
CMGC CSNK2A2 CSK22_HUMAN Casein kinase II subunit alpha' 7AT9A Active DFGin BLAminus in-in in-in 42J 4B0 42J Allosteric Type1 Allosteric
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7O7KA Active DFGin BLAminus in-in in-in 6ZV LI Type1 Allosteric
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7O7KB Active DFGin BLAminus in-in in-in 6ZV LI Type1 Allosteric
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7ZH8A Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7ZH8B Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7ZH8C Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric
CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7ZH8D Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 7W5OB Active DFGin BLAminus in-in in-in 6GI Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QAHA Inactive DFGin BLAminus in-out in-in HVB HVB Allosteric Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QALA Active DFGin BLAminus in-in in-in HV2 HV2 Allosteric Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6NBSA Inactive DFGin BLAminus out-out in-in KJ7 KJ4 Allosteric Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 8AOGA Active DFGin BLAminus in-in in-in N29 N29 N29 Allosteric Allosteric Type1
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6G8XA Active DFGin BLAminus out-in in-in EQT EQT Allosteric Type1
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QA1A Inactive DFGin BLAminus out-out in-in HVK HVK HVK HVK HVK HVK HVK Allosteric Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QA4A Inactive DFGin BLAminus out-out in-in HRZ HRZ HRZ HRZ Allosteric Type1 Allosteric Type3
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 5WP1A Inactive DFGin BLAminus out-out in-in B7S BEZ Type1 Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6Q7TA Inactive DFGin BLAminus in-out in-in HOW HOW Type1 Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QAGA Inactive DFGin BLAminus out-out in-in HUH HUH Type1 Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 8AOAA Active DFGin BLAminus out-in in-in N83 OZU Type1 Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 8AODA Active DFGin BLAminus in-in in-in NY0 NYI Type1 Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 8AOHA Active DFGin BLAminus out-in in-in N96 N96 Type1 Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 8AOIA Active DFGin BLAminus out-in in-in NX0 NX0 Type1 Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 7XC1A Active DFGin BLAminus in-in in-in 5ID B8Z Type1 Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 7X4UA Inactive DFGin BLAminus in-out in-in 5ID 8DK BTB Type1 Allosteric Allosteric
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QAQA Inactive DFGin BLAminus out-out in-in HVQ HVQ Type3 Allosteric
CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 4Z9LA Inactive DFGin ABAminus out-out none-out ANP 880 Allosteric Type1
CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 8BZPA Inactive DFGin ABAminus in-none out-out SWM C15 Type1 Allosteric
CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 6EMHA Inactive DFGin ABAminus in-in out-out BGE C15 Type1 Allosteric
CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 6EMHB Inactive DFGin ABAminus in-in out-out BGE C15 Type1 Allosteric
CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 6EQ9A Inactive DFGin ABAminus in-out out-out ACP C15 Type1 Allosteric
CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 8BZPB Inactive DFGin ABAminus in-out none-none SWM C15 C15 Type1 Type1 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N68A Inactive DFGin BLBminus in-in none-none 8OK Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3NEWA Inactive DFGin BLBplus in-in none-none 3NE Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH2A Inactive DFGin BLBplus in-in none-out IRG 0OK Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HL7A Inactive DFGin BLBplus in-in none-out I47 I46 Type1 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ROCA Inactive DFGin BLBplus in-out none-out 29A 29B Type1 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HLLA Inactive DFGin BLBplus in-out none-out I45 I46 PO2 Type1 Allosteric Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2RG6A Inactive DFGin BLBplus in-in out-out 287 287 Type1.5_Back Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4E6AA Inactive DFGin None in-in none-none 0O9 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4E6CA Inactive DFGin None in-in none-none 0O8 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N67A Inactive DFGin None in-in none-out 8ON Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4DLIA Inactive DFGin None in-in none-out IRG IRG Allosteric Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH4A Inactive DFGin None in-in none-out IRG 0OL Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3C5UA Inactive DFGin None in-in none-out P41 P41 Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EWQA Inactive DFGin None in-in out-out MWL MWL Type1 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4R3CA Inactive DFGin None in-out none-out 3GF 3GF Type1 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HP2A Inactive DFGin None in-in none-out P36 I46 I46 Type1 Allosteric Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HP5A Inactive DFGin None in-in none-out 52P I46 I46 Type1 Allosteric Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH9A Inactive DFGinter None in-out none-out IRG 0OQ Allosteric Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EHVA Inactive DFGinter None in-none none-out 0SJ 0SJ IRG 0SJ Type3 Allosteric Allosteric Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6QDZA Inactive DFGout BBAminus in-in none-out I46 HYK Allosteric Type2
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6QE1A Inactive DFGout BBAminus in-in none-out I46 HYW Allosteric Type2
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3K3IA Inactive DFGout BBAminus in-in none-out JZJ I46 I46 Type3 Allosteric Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N64A Inactive DFGout None in-in none-out 8OH Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N66A Inactive DFGout None in-in none-out BW1 B96 Allosteric Type2
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH8A Inactive DFGout None in-in none-out IRG 0OP 0OP Allosteric Type3 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2YISA Inactive DFGout None in-in none-out YIS I46 Type2 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2YIWA Inactive DFGout None in-in none-out YIW I46 Type2 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3K3JA Inactive DFGout None in-in none-out F4C I46 Type2 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4E8AA Inactive None None in-in none-none 0OA Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N63A Inactive None None in-in none-out 8OW Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5O8UA Inactive None None in-in none-out 9O5 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5O8VA Inactive None None in-in none-out 9O2 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N65A Inactive None None in-in none-out 8OT 8OT Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4DLJA Inactive None None in-in none-out 6RG 6RG Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH5A Inactive None None in-in none-out IRG 0OM Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH6A Inactive None None in-in none-out IRG 0ON Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH7A Inactive None None in-in none-out IRG 0OO Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH3A Inactive None None in-out none-out NAR IRG Type1 Allosteric
CMGC MAPK3 MK03_HUMAN Mitogen-activated protein kinase 3 6GESA Active DFGin BLAminus in-in in-in 6H3 EWH Type1 Allosteric
CMGC MAPK8 MK08_HUMAN Mitogen-activated protein kinase 8 4QTDA Inactive DFGin ABAminus in-out out-out 38Z ANP Type1 Allosteric
CMGC MAPK8 MK08_HUMAN Mitogen-activated protein kinase 8 3O2MA Active DFGin BLAminus in-in in-in 46A Allosteric
CMGC MAPK8 MK08_HUMAN Mitogen-activated protein kinase 8 3O2MB Active DFGin BLAminus in-in in-in 46A Allosteric
OTHER BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 4W9WA Active DFGin BLAminus in-in in-in YDJ YDJ Type1 Allosteric
OTHER CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 6YA8A Active DFGin BLAminus in-in in-in ADP BEF Type1 Allosteric
OTHER GAK GAK_HUMAN Cyclin-G-associated kinase 5Y80A Inactive DFGin ABAminus in-in in-out IRE IRE Type1 Allosteric
OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 4MWIA Inactive DFGin BLBminus in-in out-out PXN Allosteric
OTHER STK16 STK16_HUMAN Serine/threonine-protein kinase 16 2BUJA Active DFGin BLAminus in-in in-in STU STU Type1 Allosteric
OTHER TTK TTK_HUMAN Dual specificity protein kinase TTK 7LQDA Inactive DFGin ABAminus out-out out-out YB4 TOE Type1 Allosteric
OTHER ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 6QASB Active DFGin BLAminus in-in in-in 34W 34W Type1 Allosteric
OTHER ULK3 ULK3_HUMAN Serine/threonine-protein kinase ULK3 6FDYU Inactive DFGin BLAminus out-out in-in DB8 DB8 Type1 Allosteric
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4MNEH Inactive DFGin BLBplus out-out out-out ACP 573 573 Type1 Type3 Allosteric
STE MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YZ4A Inactive DFGout None in-out out-out 1E8 Allosteric
STE MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YG2A Inactive None None in-out out-none 1E8 8E8 Allosteric Type1.5_Front
STE MAP3K14 M3K14_HUMAN Mitogen-activated protein kinase kinase kinase 14 8YHWD Active DFGin BLAminus in-in in-in AGS PE8 Type1 Allosteric
STE STK4 STK4_HUMAN Serine/threonine-protein kinase 4 6YATA Active DFGin BLAminus in-in in-in 3FX OJ5 Allosteric Type1
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6SZMA Inactive DFGin BLAminus in-out in-in M2Z M2Z M2Z Allosteric Allosteric Type1
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7QB Inactive DFGin BLAminus in-out in-in XJM LU8 XJM Allosteric Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7BB Inactive DFGin BLAminus in-out in-in LU8 XH7 Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7CB Inactive DFGin BLAminus in-out in-in LU8 T5Y Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7DB Inactive DFGin BLAminus in-out in-in LU8 XHD Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7EB Inactive DFGin BLAminus in-out in-in LU8 XEA Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7KB Inactive DFGin BLAminus in-out in-in LU8 XEJ Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7MB Inactive DFGin BLAminus in-out in-in LU8 HVK Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7NB Inactive DFGin BLAminus in-out in-in LU8 2AI Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7SB Inactive DFGin BLAminus in-out in-in LU8 09V Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7VB Inactive DFGin BLAminus in-out in-in LU8 XH1 Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7XB Inactive DFGin BLAminus in-out in-in LU8 LGA Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7ZB Inactive DFGin BLAminus in-out in-in LU8 BYZ Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S82B Inactive DFGin BLAminus in-out in-in LU8 LAC Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S86B Inactive DFGin BLAminus in-out in-in LU8 XK7 Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S87B Inactive DFGin BLAminus in-out in-in LU8 XKD Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S88B Inactive DFGin BLAminus in-out in-in LU8 XKS Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S8AB Inactive DFGin BLAminus in-out in-in LU8 XKY Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S75B Inactive DFGin BLAminus in-out in-in LU8 HUH HUH Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S79A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7AB Inactive DFGin BLAminus in-out in-in LU8 T5V T5V Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7EA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7FA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7FB Inactive DFGin BLAminus in-out in-in LU8 XH4 XH4 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7GA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7OA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7QA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7UA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7UB Inactive DFGin BLAminus in-out in-in LU8 XGY XGY Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7VA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7WA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7YA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S80A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S80B Inactive DFGin BLAminus in-out in-in LU8 XGM XGM Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S82A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S87A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S88A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S9KA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6SRHB Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6Z36A Inactive DFGin BLAminus in-out in-in Q5Z Q5Z Q5Z Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S77A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 BAQ Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7DA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XHD Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7JA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XHG Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7KA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XEJ Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7LA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XHJ Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7MA Inactive DFGin BLAminus in-out in-in LU8 LU8 HVK HVK Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7NA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 2AI Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7PA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 V1L Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7SA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 09V Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7TB Inactive DFGin BLAminus in-out in-in LU8 XGJ XGJ XGJ Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7XA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 LGA Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S86A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XK7 Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S89A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XKV Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S8AA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XKY Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S8BB Inactive DFGin BLAminus in-out in-in LU8 XFV XFV XFV Type1 Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S75A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HUH HUH Type1 Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7AA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 T5V T5V Type1 Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7BA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XH7 XH7 Type1 Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7HA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HVB HVB Type1 Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7ZA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 BYZ BYZ Type1 Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S81B Inactive DFGin BLAminus in-out in-in LU8 XJV XJV XJV XJV Type1 Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7CA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 T5Y T5Y T5Y Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7IA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HV2 HV2 HV2 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7TA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XGJ XGJ XGJ Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7YB Inactive DFGin BLAminus in-out in-in LU8 XJP XJP XJP XJP XJP Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7RB Inactive DFGin BLAminus in-out in-in LU8 XGS XGS XGS XGS XGS XGS Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S85A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XK4 XK4 XK4 XK4 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S8BA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XFV XFV XFV XFV Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7RA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XGS XGS XGS XGS XGS Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7IB Inactive DFGin BLAminus in-out in-in LU8 HV2 HV2 HV2 HV2 HV2 HV2 HV2 HV2 HV2 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S78A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XGV XGV XGV Type1 Allosteric Allosteric Allosteric Allosteric Type1
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S81A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XJV XJV Type1 Allosteric Allosteric Allosteric Type1
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S76A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 02A 02A Type1 Allosteric Allosteric Allosteric Type1.5_Back
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7LB Inactive DFGin BLAminus in-out in-in LU8 XHJ XHJ XHJ XHJ Type1 Allosteric Allosteric Allosteric Type3
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S84A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XK1 Type1 Allosteric Allosteric Type1
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S83A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XJY Type1 Allosteric Allosteric Type3
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S85B Inactive DFGin BLAminus in-out in-in LU8 XK4 XK4 XK4 Type1 Type1 Allosteric Allosteric
TKL BMPR2 BMPR2_HUMAN Bone morphogenetic protein receptor type-2 6UNPA Active DFGin BLAminus in-in in-in ADP ADP Type1 Allosteric
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6P7GB Inactive DFGout BBAminus in-in out-out E7M NHE Type2 Allosteric
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 7C2WA Inactive DFGin BLAminus in-out in-in YTH FJ9 Allosteric Type1
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 7C2WB Inactive DFGin BLAminus in-out in-in YTH FJ9 Allosteric Type1
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 7C2WC Inactive DFGin BLAminus in-out in-in YTH FJ9 Allosteric Type1
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 7C2WD Inactive DFGin BLAminus in-out in-in YTH FJ9 Allosteric Type1
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 4YO6D Inactive DFGin BLAminus in-out in-in 4GD 4GD Type1 Allosteric
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6TIAA Inactive DFGin BLAminus in-out in-in ND2 ND2 ND2 ND2 Type1 Allosteric Allosteric Allosteric
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6TIAB Inactive DFGin BLAminus in-out in-in ND2 ND2 ND2 ND2 Type1 Allosteric Allosteric Allosteric
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2HZ4A Inactive DFGin BLAminus in-out in-in 4ST Allosteric
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2HZ4C Active DFGin BLAminus in-in in-in 4ST Allosteric
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GB Active DFGin BLAminus in-in in-in STI 1N1 Allosteric Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8SSNB Inactive DFGin BLBplus out-out none-none AY7 SKI Allosteric Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8SSNA Inactive DFGin BLBplus out-out out-none AY7 SKI Allosteric Type1.5_Back
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GA Inactive DFGinter None in-out out-in STI 1N1 Allosteric Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GC Inactive DFGinter None in-none out-in STI 1N1 Allosteric Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 5HU9A Inactive DFGout BBAminus in-in out-out 66K 66K Type2 Allosteric
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3PYYA Inactive DFGout BBAminus in-in out-in STI 3YY Type2 Allosteric
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3PYYB Inactive DFGout BBAminus in-in none-out STI 3YY Type2 Allosteric
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6NPEA Inactive DFGout BBAminus in-in out-in STI KWD Type2 Allosteric
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6NPEB Inactive DFGout BBAminus in-in none-in STI KWD Type2 Allosteric
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6NPUA Inactive DFGout BBAminus in-in out-in STI KWV Type2 Allosteric
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6NPUB Inactive DFGout BBAminus in-in none-in STI KWV Type2 Allosteric
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6NPVA Inactive DFGout BBAminus in-in out-in STI KWP Type2 Allosteric
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6NPVB Inactive DFGout BBAminus in-in none-in STI KWP Type2 Allosteric
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 5MO4A Inactive DFGout None in-in none-out NIL AY7 Type2 Allosteric
TYR ABL2 ABL2_HUMAN Tyrosine-protein kinase ABL2 2XYNB None DFGin BLAminus in-none in-in VX6 VX6 VX6 Type1 Allosteric Allosteric
TYR ABL2 ABL2_HUMAN Tyrosine-protein kinase ABL2 2XYNC None DFGin BLAminus in-none in-in VX6 VX6 VX6 Type1 Allosteric Allosteric
TYR ABL2 ABL2_HUMAN Tyrosine-protein kinase ABL2 3GVUA Inactive DFGout BBAminus in-in out-in STI STI Type2 Allosteric
TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 4TT7A Inactive DFGin ABAminus in-in out-out COM COM Allosteric Allosteric
TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 7JY4A Inactive DFGin ABAminus in-out out-out W47 W47 Allosteric Type1
TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 4CNHB Inactive DFGin ABAminus in-in out-out 3U9 3U9 Type1 Allosteric
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 3PJ1A Inactive DFGin BLAplus in-in none-out LHL LHL Type1 Allosteric
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 8EJBA Inactive DFGin BLBplus out-out out-out WKC PD Type1 Allosteric
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6X3NA Inactive DFGin BLBplus out-out none-in ULV 5WE Type1 Allosteric
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5FBOA Inactive DFGin BLBplus out-out none-out 5WH 5WE Type1.5_Back Allosteric
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 8FLNA Inactive DFGin BLBplus out-out out-out Y7W BTB Type1.5_Front Allosteric
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5FBNC Inactive DFGin BLBplus out-out out-out 5WF 5WE Type1.5_Front Allosteric
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6X3OA Inactive DFGin BLBplus out-out out-out ULY 5WE Type1.5_Front Allosteric
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6X3OB Inactive DFGin BLBplus out-out out-out ULY 5WE Type1.5_Front Allosteric
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 8FLLA Inactive DFGin BLBplus out-none out-out Y7W BTB Type1.5_Front Allosteric
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5FBND Inactive DFGin BLBplus out-out out-in 5WF 5WE 5WE 5WE Type1.5_Front Allosteric Allosteric Allosteric
TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6X3PA Inactive DFGin BLBplus out-out out-out UM4 UM4 BTB Type1.5_Front Allosteric Type1
TYR CSF1R CSF1R_HUMAN Macrophage colony-stimulating factor 1 receptor 8CGCA Inactive DFGout BBAminus in-in out-in LMR UIK Allosteric Type1
TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 3ZOSA Inactive DFGout BBAminus in-in out-in 0LI 0LI Type2 Allosteric
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV4A Active DFGin BLAminus in-in in-in PE5 MWU Allosteric Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV6A Active DFGin BLAminus in-in in-in PE5 N86 Allosteric Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV7A Active DFGin BLAminus in-in in-in PE5 N8O Allosteric Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV8A Active DFGin BLAminus in-in in-in PE5 N99 Allosteric Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV9A Active DFGin BLAminus in-in in-in PE5 N9L Allosteric Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV1A Active DFGin BLAminus in-in in-in PE5 N6N Allosteric Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV3A Active DFGin BLAminus in-in in-in PE5 MWU Allosteric Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV5A Active DFGin BLAminus in-in in-in PE5 N7C Allosteric Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6JX0A Active DFGin BLAminus in-in in-in YY3 YY3 Type1 Allosteric
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4G5JA Active DFGin BLAminus in-in in-in 0WN 0WM 0WM Type1 Allosteric Allosteric
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5X2AA Inactive DFGin BLBtrans out-out out-in 7XO ANP Type1 Allosteric
TYR EPHA3 EPHA3_HUMAN Ephrin type-A receptor 3 6IN0A Inactive DFGin BLAminus in-out in-in O4B O4B Type3 Allosteric
TYR FES FES_HUMAN Tyrosine-protein kinase Fes/Fps 3CBLA Active DFGin BLAminus in-in in-in STU STU STU Type1 Allosteric Allosteric
TYR FES FES_HUMAN Tyrosine-protein kinase Fes/Fps 3CD3A Active DFGin BLAminus in-in in-in STU STU STU Type1 Allosteric Allosteric
TYR FGFR2 FGFR2_HUMAN Fibroblast growth factor receptor 2 8SWEA Active DFGin BLAminus in-in in-in GSH WXQ Allosteric Type1
TYR FGFR3 FGFR3_HUMAN Fibroblast growth factor receptor 3 8UDTA Inactive DFGin BLAplus in-out out-out MLT MLT WGF Allosteric Allosteric Type1.5_Front
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0A Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0B Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0C Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0D Inactive DFGout None in-out out-in CCX CCX Type3 Allosteric
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5HEZA Inactive DFGin ABAminus in-in in-out 1M3 1M3 Allosteric Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5HEZB Inactive DFGin ABAminus in-in in-out 1M3 1M3 Allosteric Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5HEZD Inactive DFGin ABAminus in-in in-out 1M3 1M3 Allosteric Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5HEZC Inactive DFGin ABAminus in-in in-out 1M3 1M3 Type1 Allosteric
TYR MET MET_HUMAN Hepatocyte growth factor receptor 4IWDA Inactive DFGin ABAminus in-in in-in AME 1JC Allosteric Type1
TYR MET MET_HUMAN Hepatocyte growth factor receptor 3Q6UA Inactive DFGin BLBminus in-out none-in AME Allosteric
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6DKGA Inactive DFGout BBAminus in-out none-in 22L GO7 Allosteric Type2
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6DKIA Inactive DFGout BBAminus in-out out-in 22L GOD Allosteric Type2
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D1ZA Inactive DFGout BBAminus in-out out-in FQD FQM Allosteric Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D20A Inactive DFGout None out-out out-in FQD FQG Allosteric Type3
TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 4OLIA Active DFGin BLAminus in-in in-in 2TT 2TT Allosteric Type1

Human and Non-human protein kinases in complex with Allosteric ligands

Total number of genes: 80
Total number of chains: 675
Spatial Label Dihedral Label AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Total
DFGin BLAminus 59 82 3 136 0 0 2 87 21 22 412
DFGin BLAplus 0 0 0 0 0 0 0 0 2 0 2
DFGin ABAminus 8 13 0 7 0 0 0 0 8 13 49
DFGin BLBminus 0 6 0 39 0 0 0 0 1 3 49
DFGin BLBplus 0 0 0 19 0 0 1 1 14 4 39
DFGin BLBtrans 0 0 0 4 0 0 0 0 1 0 5
DFGin None 2 7 0 13 0 0 0 0 3 7 32
DFGinter BABtrans 0 0 0 0 0 0 0 0 0 0 0
DFGinter None 1 0 0 2 0 0 0 0 2 0 5
DFGout BBAminus 4 0 0 4 0 0 0 1 29 0 38
DFGout None 1 0 0 9 0 0 1 0 3 0 14
None None 6 1 0 12 0 0 1 8 2 0 30
Total - 81 109 3 245 0 0 5 97 86 49 675
Download as tsv
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment


Organism Group Gene UniprotID Protein PDB Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActloopCT Ligand Type
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZTC Inactive DFGin BLBminus out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUB Inactive DFGin BLBminus out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUC Inactive DFGin BLBminus out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUD Inactive DFGin BLBminus out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZTD Inactive DFGin BLBminus out-out out-out CPS CPS CPS Type1 Allosteric Allosteric
Arabidopsis thaliana OTHER BIR2 BIR2_ARATH Inactive LRR receptor-like serine/threonine-protein kinase BIR2 4L68A Inactive DFGin BLBminus out-out out-in PDO Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5TA Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5TD Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5TI Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5TJ Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5TM Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5UC Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5VC Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J6IA Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2GNHA Inactive DFGin ABAminus in-in in-in H52 H52 Type1 Allosteric
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2VO7A Active DFGin BLAminus in-in in-in M05 M05 Allosteric Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 1Q8UA Active DFGin BLAminus in-in in-in H52 H52 Type1 Allosteric
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 3BWJA Active DFGin BLAminus in-in in-in ARX ARX Type1 Allosteric
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 4Z83E Active DFGin BLAminus in-in in-in 4L7 4L7 Type1 Allosteric
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2VO0A Active DFGin BLAminus in-in in-in M03 M03 Type1 Allosteric
Bos taurus TYR BTK Q3ZC95_BOVIN Tyrosine-protein kinase 4Y95B Inactive DFGin BLBplus out-out out-out 746 PE4 Type1 Allosteric
Bos taurus TYR BTK Q3ZC95_BOVIN Tyrosine-protein kinase 4Y95C Inactive DFGin BLBplus out-out out-out 746 PE4 Type1 Allosteric
Caenorhabditis elegans CAMK TWITCHIN UNC22_CAEEL Twitchin 3UTOB Inactive DFGin ABAminus out-out in-out P33 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6I2BA Inactive DFGin ABAminus in-in in-in 9LQ 9LQ Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3NA Active DFGin BLAminus in-in in-in 152 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N1GA Active DFGin BLAminus in-in in-in 8G5 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N1NA Active DFGin BLAminus in-in in-in 8G8 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3IA Active DFGin BLAminus in-in in-in BJQ Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3KA Active DFGin BLAminus in-in in-in GGB Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3RA Active DFGin BLAminus in-in in-in CDT Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6Z08A Active DFGin BLAminus in-in in-in NPO Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N37A Active DFGin BLAminus in-in in-in 8JT 8JT Allosteric Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3GA Active DFGin BLAminus in-in in-in 8KB 8KB Allosteric Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3TA Active DFGin BLAminus in-in in-in 8K2 8K2 Allosteric Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 7AXVA Active DFGin BLAminus in-in in-in S95 S95 Allosteric Type1
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3OA Active DFGin BLAminus in-in in-in 5AO 5AO 5AO Allosteric Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5M0LA Active DFGin BLAminus in-in in-in 7CT 7CT Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5MHIA Active DFGin BLAminus in-in in-in 7N9 7N9 Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N1KA Active DFGin BLAminus in-in in-in 489 489 Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N32A Active DFGin BLAminus in-in in-in 8K5 8K5 Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3FA Active DFGin BLAminus in-in in-in 463 463 Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3QA Active DFGin BLAminus in-in in-in 3AB 3AB Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6SNXA Active DFGin BLAminus in-in in-in UNU UNU Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6YOTA Active DFGin BLAminus in-in in-in P4W P4W Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6ZN0A Active DFGin BLAminus in-in in-in NTN NTN Type1 Allosteric
Danio rerio OTHER POMK SG196_DANRE Protein O-mannose kinase 5GZAA Inactive DFGin None none-none in-out ADP ZZ1 Type1 Allosteric
Dictyostelium discoideum TKL ROCO4 ROCO4_DICDI Probable serine/threonine-protein kinase roco4 4F1TA Inactive DFGin BLAminus in-in in-out H52 H52 Type1 Allosteric
Dictyostelium discoideum TKL ROCO4 ROCO4_DICDI Probable serine/threonine-protein kinase roco4 4F1MA Inactive DFGin BLAminus in-in in-out ACP BTB Type1 Allosteric
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 2QLQA Inactive DFGin None none-none none-none SR2 SR2 Type1 Allosteric
Homo sapiens AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 3O96A Inactive DFGout BBAminus none-none out-none IQO Allosteric
Homo sapiens AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6HHHA Inactive DFGout BBAminus none-none out-out G4Q Allosteric
Homo sapiens AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6HHJA Inactive DFGout BBAminus out-out out-out G4H Allosteric
Homo sapiens AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6S9WA Inactive DFGout BBAminus out-out out-out L1Z Allosteric
Homo sapiens AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 5KCVA Inactive DFGout None none-none none-none 6S1 Allosteric
Homo sapiens AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6HHFA Inactive None None none-none out-none G4K Allosteric
Homo sapiens AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6HHGA Inactive None None none-none out-out G4T Allosteric
Homo sapiens AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6HHIA Inactive None None none-none out-out G4N Allosteric
Homo sapiens AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 6S9XA Inactive None None none-none out-out L1W Allosteric
Homo sapiens AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 7NH4A Inactive None None none-none out-out UCE Allosteric
Homo sapiens AGC AKT1 AKT1_HUMAN RAC-alpha serine/threonine-protein kinase 7NH5A Inactive None None none-none out-out UC8 Allosteric
Homo sapiens AGC CDC42BPB MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta 3TKUA Active DFGin BLAminus in-in in-in M77 M77 Type1 Allosteric
Homo sapiens AGC CDC42BPB MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta 3TKUB Active DFGin BLAminus in-in in-in M77 M77 Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXA Active DFGin BLAminus in-in in-in 1F8 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXB Active DFGin BLAminus in-in in-in 1F8 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXC Active DFGin BLAminus in-in in-in 1F8 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXD Active DFGin BLAminus in-in in-in 1F8 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXE Active DFGin BLAminus in-in in-in 1F8 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXF None DFGin BLAminus in-none in-in 1F8 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXG Active DFGin BLAminus in-in in-in 1F8 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORXH Active DFGin BLAminus in-in in-in 1F8 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 8DQTA Active DFGin BLAminus in-in in-in U35 U35 U35 Allosteric Allosteric Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZA Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZB Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZC Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3ORZD Active DFGin BLAminus in-in in-in 2A2 BI4 Allosteric Type1
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3OTUA Active DFGin BLAminus in-in in-in J30 BI4 Allosteric Type1.5_Front
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 3HRFA Active DFGin BLAminus in-in in-in ATP P47 Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4A06A Active DFGin BLAminus in-in in-in ATP A06 Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4AW0A Active DFGin BLAminus in-in in-in ATP MJF Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4AW1A Active DFGin BLAminus in-in in-in ATP 21O Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4RQKA Active DFGin BLAminus in-in in-in ATP R1S Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4RQVA Active DFGin BLAminus in-in in-in ATP R2S Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 5LVOA Active DFGin BLAminus in-in in-in ATP 78W Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4CT1A None DFGin BLAminus in-none in-in ATP 31S Type1 Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4XX9A Active DFGin BLAminus in-in in-in ATP RF4 RF4 Type1 Allosteric Allosteric
Homo sapiens AGC PDPK1 PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 4A07A Active DFGin BLAminus in-in in-in ATP AZ7 AZ7 Type1 Allosteric Allosteric
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 5IZJA Inactive DFGin BLAminus in-out in-in 6J9 Allosteric
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 5IZJB Inactive DFGin BLAminus out-out in-in 6J9 Allosteric
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 5J5XA Active DFGin BLAminus in-in in-in 6J9 Allosteric
Homo sapiens AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4UA Inactive DFGin ABAminus in-in in-in EX6 Allosteric
Homo sapiens AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4UB Inactive DFGin ABAminus in-in in-in EX6 Allosteric
Homo sapiens AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4WA Inactive DFGin ABAminus in-in in-in EZJ Allosteric
Homo sapiens AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4WB Inactive DFGin ABAminus in-in in-in EZJ Allosteric
Homo sapiens AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4TA Inactive DFGin ABAminus in-in in-in PCG ATP Allosteric Type1
Homo sapiens AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4TB Inactive DFGin ABAminus in-in in-in PCG ATP Allosteric Type1
Homo sapiens AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4VA Inactive DFGin BLAminus in-in in-out EXZ Allosteric
Homo sapiens AGC PRKG1 KGP1_HUMAN cGMP-dependent protein kinase 1 7T4VB Active DFGin BLAminus in-in in-in EXZ Allosteric
Homo sapiens AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G77A Inactive DFGin None none-none out-in ANP ANP Allosteric Type1
Homo sapiens AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G77B Inactive DFGin None none-none out-in ANP ANP Allosteric Type1
Homo sapiens AGC RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G76A Inactive DFGinter None none-none out-in ANP ANP Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DPVA Inactive DFGin ABAminus out-in in-out 5DN SKE Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DR6A Inactive DFGin ABAminus out-in in-out 5E1 SKE Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DN3A Inactive DFGin BLAminus in-in in-out 5DN ATP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1EA Inactive DFGin BLAminus in-in in-out T0X ATP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DT4A Inactive DFGin BLAminus in-in in-out 5DN ATP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1MA Inactive DFGin BLAminus in-in in-out T4X ADP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8SSPA Inactive DFGin BLAminus out-out in-in PDO 627 Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DOSA Inactive DFGin BLAminus in-in in-out 5DN ATP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DR2A Inactive DFGin BLAminus in-in in-out 5E1 ATP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1DA Inactive DFGin BLAminus in-in in-out T2F ADP T5L Allosteric Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1GA Inactive DFGin BLAminus in-in in-out T3I ADP T5L Allosteric Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1HA Inactive DFGin BLAminus in-in in-out T3U ADP T5L Allosteric Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1KA Inactive DFGin BLAminus in-in in-out T4O ADP T5L Allosteric Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6VPLA Inactive DFGin BLAminus out-out in-out ANP R7D Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6VPLB Inactive DFGin BLAminus out-out in-out ANP R7D Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6VPMA Inactive DFGin BLAminus out-out in-out AMP R74 Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6VPMB Inactive DFGin BLAminus out-out in-out AMP R74 Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DR9A Inactive DFGin BLAminus out-out out-out SKE 5E2 Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORLA Inactive DFGin BLAminus in-in in-out ADP A4W Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORNA Inactive DFGin BLAminus in-in in-out ADP A5E Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OROA Inactive DFGin BLAminus in-in in-out ADP A5H Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORPA Inactive DFGin BLAminus in-in in-out ADP A5K Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORRA Inactive DFGin BLAminus in-in in-out ADP A5Q Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORSA Inactive DFGin BLAminus in-in in-out ADP A5W Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORTA Inactive DFGin BLAminus in-in in-out ADP A5Z Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORVA Inactive DFGin BLAminus in-in in-out ADP A65 Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORWA Inactive DFGin BLAminus in-in in-out ADP A6E Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORXA Inactive DFGin BLAminus in-in in-out ADP A6H Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORYA Inactive DFGin BLAminus in-in in-out ADP AY4 Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORZA Inactive DFGin BLAminus in-in in-out ADP A6W Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS0A Inactive DFGin BLAminus in-in in-out ADP A6Z Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS1A Inactive DFGin BLAminus in-in in-out ADP A7H Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS2A Inactive DFGin BLAminus in-in in-out ADP A7K Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS3A Inactive DFGin BLAminus in-in in-out ADP A7N Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS4A Inactive DFGin BLAminus in-in in-out ADP A8H Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS6A Inactive DFGin BLAminus in-in in-out ADP A7Q Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OSEA Inactive DFGin BLAminus in-in in-out ADP A98 Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OSFA Inactive DFGin BLAminus in-in in-out ADP A9E Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OSDA Inactive DFGin BLAminus in-in in-out ADP A9B Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS5A Inactive DFGin BLAminus in-in in-out ADP A8K Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6R49A Inactive DFGin BLAminus in-in in-out ADP JSB Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4AA Inactive DFGin BLAminus in-in in-out ADP JRT Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4BA Inactive DFGin BLAminus in-in in-out ADP JSN Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4CA Inactive DFGin BLAminus in-in in-out ADP JRQ Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4DA Inactive DFGin BLAminus in-in in-out ADP JRW Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 7ZTLA Active DFGin BLAminus in-in in-in ADP BCN Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8OF5A Inactive DFGin BLAminus in-in in-out ADP MPO Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C14A Inactive DFGin BLAminus in-in in-out ADP T5L T0L Type1 Allosteric Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C15A Inactive DFGin BLAminus in-in in-out ADP T4C T5L Type1 Allosteric Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1FA Inactive DFGin BLAminus in-in in-out ADP T5L T2O Type1 Allosteric Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1IA Inactive DFGin BLAminus in-in in-out ADP T1L T5L Type1 Allosteric Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OBJA Inactive DFGin None out-out in-out ATP 9QK Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OBRA Inactive None None out-out out-out 9QT SKE Allosteric Type1
Homo sapiens CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 3JVRA Active DFGin BLAminus in-in in-in AGX Allosteric
Homo sapiens CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 3JVSA Inactive DFGin BLAminus in-out in-in AGY Allosteric
Homo sapiens CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 3F9NA Active DFGin BLAminus in-in in-in 38M Allosteric
Homo sapiens CAMK CHEK1 CHK1_HUMAN Serine/threonine-protein kinase Chk1 5F4NA Active DFGin BLAminus in-in in-in 5UY 5UY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CA None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CB None DFGin BLAminus in-out in-none PDY PDY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CC None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CD None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CE None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CF None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CG None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CH None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CI None DFGin BLAminus in-out in-none PDY PDY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CJ None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CK None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 3A2CL None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 6T8XA Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 6T8XB None DFGin BLAminus in-in in-none B97 MW8 Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 6T8XC None DFGin BLAminus in-in in-none B97 MW8 Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 6T8XD Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 6T8XE Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 6T8XF Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric
Homo sapiens CAMK PIM1 PIM1_HUMAN Serine/threonine-protein kinase pim-1 4I41A Inactive DFGin ABAminus in-in in-in MIX MIX Type1 Allosteric
Homo sapiens CAMK PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 6C9FA Inactive DFGin ABAminus out-out in-in R34 STU Allosteric Type1
Homo sapiens CAMK PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 6C9GA Inactive DFGin BLAminus out-out in-in R93 STU Allosteric Type1
Homo sapiens CAMK PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 6C9HA Inactive DFGin BLAminus out-out in-in R34 STU Allosteric Type1
Homo sapiens CAMK PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 6C9JA Active DFGin BLAminus out-in in-in R34 STU Allosteric Type1
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 5ISOA Inactive DFGin ABAminus out-none in-in STU 992 Type1 Allosteric
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 5ISOC Inactive DFGin ABAminus out-none in-in STU 992 Type1 Allosteric
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 6B1UC Inactive DFGin ABAminus out-out in-in STU CG7 Type1 Allosteric
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 6B2EA None DFGin BLAminus out-none in-out STU CG7 Type1 Allosteric
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 4CFEA Inactive DFGin BLAminus out-out in-in STU 992 Type1 Allosteric
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 4CFEC Inactive DFGin BLAminus out-out in-in STU 992 Type1 Allosteric
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 7MYJA Inactive DFGin BLBminus out-in in-in 4O7 ZQV Type1 Allosteric
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 5EZVA Inactive DFGin None in-in in-in STU C1V Type1 Allosteric
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 5EZVC Inactive DFGin None out-in in-in STU C1V Type1 Allosteric
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 4ZHXC Inactive DFGin None out-out in-out 4O7 C1V Type1 Allosteric
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 6B1UA Inactive DFGin None out-in in-in STU CG7 Type1 Allosteric
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 4CFFC Inactive DFGin None out-out in-in STU C1V Type1 Allosteric
Homo sapiens CAMK RPS6KA5 KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 7UP6A None DFGin BLAminus in-in in-none SUU OXM OXM Type1 Allosteric Allosteric
Homo sapiens CK1 CSNK1G1 KC1G1_HUMAN Casein kinase I isoform gamma-1 2CMWA Active DFGin BLAminus in-in in-in OLP OLP OLP Type1 Allosteric Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8VQ3A Active DFGin BLAminus in-in in-in A1AC4 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8VQ4A Active DFGin BLAminus in-in in-in A1AC5 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXFA Inactive DFGin BLBminus out-out out-out 2AN 2AN Allosteric Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXZA Inactive DFGin BLBminus out-out out-out 2AN 2AN JWS Allosteric Type3 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4D1ZA Inactive DFGin BLBminus out-none none-none WG8 WG8 Type1 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5FP5A Inactive DFGin BLBminus out-none none-none 1Y6 1Y6 Type1 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5FP6A Inactive DFGin BLBminus out-out none-out MFZ MFZ Type1 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXQA Inactive DFGin BLBminus out-out out-out 2AN 2AN 2AN Type1 Allosteric Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PY1A Inactive DFGin BLBminus out-out out-out SU9 2AN 2AN Type1 Allosteric Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EZ7A Inactive DFGin BLBminus out-out out-out STU 2AN 2AN Type1 Type3 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7UG1A Inactive DFGin BLBminus out-out out-out N5R N5R Type3 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4FKUA Inactive DFGin BLBplus out-out out-out 60K 60K Allosteric Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5OO0A Inactive DFGin BLBtrans out-out out-out 9YZ Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5OSJA Inactive DFGin BLBtrans out-out out-out AAK Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6Q4KA Inactive DFGin BLBtrans out-out out-out HHW HHW Allosteric Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6Q4DA Inactive DFGin BLBtrans out-out out-out HHT HHT HHT HHT HHT HHT Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3EZRA Inactive DFGin None out-out none-none EZR EZR Type1 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5A14A Inactive DFGout None in-in out-out LQ5 LQ5 Type2 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6Q3FA Inactive None None out-out out-out HEW Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6Q49A Inactive None None out-out out-out HGQ Allosteric
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 6TPAA Inactive DFGout BBAminus out-out out-none NZ8 NZ5 NZ5 NZ5 Type2 Allosteric Allosteric Allosteric
Homo sapiens CMGC CLK1 CLK1_HUMAN Dual specificity protein kinase CLK1 5J1WC Inactive DFGin BLAminus in-in in-out 6FB 6FB Type1 Allosteric
Homo sapiens CMGC CLK1 CLK1_HUMAN Dual specificity protein kinase CLK1 6YTGA Active DFGin BLAminus in-in in-in KHC KHC Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CT0A Active DFGin BLAminus in-in in-in 54P Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CT0B Active DFGin BLAminus in-in in-in 54P Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CTPA Active DFGin BLAminus in-in in-in 54R Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CTPB Active DFGin BLAminus in-in in-in 54R Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MMFA Active DFGin BLAminus in-in in-in JMB Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MMRB Active DFGin BLAminus in-in in-in H83 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MO6A Active DFGin BLAminus in-in in-in KXZ Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MO7A Active DFGin BLAminus in-in in-in YRA Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MODA Active DFGin BLAminus in-in in-in 86L Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OT5A Active DFGin BLAminus in-in in-in AWK Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OT5B Active DFGin BLAminus in-in in-in AWK Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OT6A Active DFGin BLAminus in-in in-in AJK Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTDA Active DFGin BLAminus in-in in-in AOW Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTDB Active DFGin BLAminus in-in in-in AOW Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTHA Active DFGin BLAminus in-in in-in AQ8 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTHB Active DFGin BLAminus in-in in-in AQ8 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTLA Active DFGin BLAminus in-in in-in AQT Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTLB Active DFGin BLAminus in-in in-in AQT Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTOA Active DFGin BLAminus in-in in-in AQW Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTOB Active DFGin BLAminus in-in in-in AQW Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OUEB Active DFGin BLAminus in-in in-in AVZ Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OUMA Active DFGin BLAminus in-in in-in AVK Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OUUA Active DFGin BLAminus in-in in-in AWN Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OUUB Active DFGin BLAminus in-in in-in AWN Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6EIIA Active DFGin BLAminus in-in in-in B5W Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6EIIB Active DFGin BLAminus in-in in-in B5W Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY5A Active DFGin BLAminus in-in in-in 1NP Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6GIHA Active DFGin BLAminus in-in in-in EZN Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSUA Active DFGin BLAminus in-in in-in AFW Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 3W8LB Active DFGin BLAminus in-in in-in IHP IHP Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CX9B Active DFGin BLAminus in-in in-in 551 551 Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MMRA Active DFGin BLAminus in-in in-in H83 H83 Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORHA Active DFGin BLAminus in-in in-in A4N A4N Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORHB Active DFGin BLAminus in-in in-in A4N A4N Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTQA Active DFGin BLAminus in-in in-in AUH AUH Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTZA Active DFGin BLAminus in-in in-in AUT AUT Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OYFA Active DFGin BLAminus in-in in-in B4Q B4Q Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CX9A Active DFGin BLAminus in-in in-in 551 551 551 Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSZA Active DFGin BLAminus in-in in-in AHK AHK AHK Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTSA Active DFGin BLAminus in-in in-in AU2 AU2 AU2 Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6EHUA Active DFGin BLAminus in-in in-in B5E B5E B5E Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6EHUB Active DFGin BLAminus in-in in-in B5E B5E B5E Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CS6A Active DFGin BLAminus in-in in-in K82 K82 K82 K82 Allosteric Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OULA Active DFGin BLAminus in-in in-in AWE AWE AWE AWE AWE AWE Allosteric Allosteric Allosteric Allosteric Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CU2A Active DFGin BLAminus in-in in-in 551 551 551 54G Allosteric Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OS8A Active DFGin BLAminus in-in in-in J27 J27 J27 ATP Allosteric Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OTRA Active DFGin BLAminus in-in in-in AU8 AU8 AU8 ATP Allosteric Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CSHA Active DFGin BLAminus in-in in-in 54E 54E ATP Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CSHB Active DFGin BLAminus in-in in-in 54E 54E ATP Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CU0A Active DFGin BLAminus in-in in-in 54R 54R 54G Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CU0B Active DFGin BLAminus in-in in-in 54R 54R 54G Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CU2B Active DFGin BLAminus in-in in-in 551 551 54G Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OS7A Active DFGin BLAminus in-in in-in A8Q A8Q ATP Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6GMDB Active DFGin BLAminus in-in in-in A8Q A8Q ATP Allosteric Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OS7B Active DFGin BLAminus in-in in-in A8Q ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6GMDA Active DFGin BLAminus in-in in-in A8Q ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY5B Active DFGin BLAminus in-in in-in 1NP 1NP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY8B Active DFGin BLAminus in-in in-in KE0 KE0 Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CVFA Active DFGin BLAminus in-in in-in 54Z ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6FVFA Active DFGin BLAminus in-in in-in 503 ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6FVGA Active DFGin BLAminus in-in in-in E8K ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY0A Active DFGin BLAminus in-in in-in KC0 ADP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AE7A Active DFGin BLAminus in-in in-in LVU ADP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AEKA Active DFGin BLAminus in-in in-in LVL ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AEMA Active DFGin BLAminus in-in in-in LVF ATP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6YPNB Active DFGin BLAminus in-in in-in ADP ADP Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5NQCA Active DFGin BLAminus in-in in-in 1KP 1KP Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 3H30A Active DFGin BLAminus in-in in-in RFZ RFZ Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7X4HA Active DFGin BLAminus in-in in-in 8BH 8BH Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7AT5A Active DFGin BLAminus in-in in-in RXE 42J Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7AT5B Active DFGin BLAminus in-in in-in RXE 42J Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CVHA Active DFGin BLAminus in-in in-in ADP IHP Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CVHB Active DFGin BLAminus in-in in-in ADP IHP Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MP8A Active DFGin BLAminus in-in in-in ADP RKN Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MP8B Active DFGin BLAminus in-in in-in ADP RKN Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORJB Active DFGin BLAminus in-in in-in ADP A4Q Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORKA Active DFGin BLAminus in-in in-in ADP A4T Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OUEA Active DFGin BLAminus in-in in-in AW5 AVZ Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6TLLA Active DFGin BLAminus in-in in-in TBS TBS Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6TLOA Active DFGin BLAminus in-in in-in NKB NKB Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6TLSA Active DFGin BLAminus in-in in-in NL2 NL2 Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6TLUAAA Active DFGin BLAminus in-in in-in NKT NKT Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6TLVA Active DFGin BLAminus in-in in-in NKW NKW Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7QGBA Active DFGin BLAminus in-in in-in 7M0 7M0 Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7QGDA Active DFGin BLAminus in-in in-in 7M0 7M0 Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MOTA Active DFGin BLAminus in-in in-in HBD HBD Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYDA Active DFGin BLAminus in-in in-in ATP KD6 Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYKA Active DFGin BLAminus in-in in-in ADP KEC Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYRA Active DFGin BLAminus in-in in-in ATP KF6 Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AECA Active DFGin BLAminus in-in in-in ATP LW3 Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSPA Active DFGin BLAminus in-in in-in ATP A9W Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSRA Active DFGin BLAminus in-in in-in ATP AFK Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MPJA Active DFGin BLAminus in-in in-in ADP IHP J2P Type1 Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OQUA Active DFGin BLAminus in-in in-in ADP A4B IHP Type1 Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY2A Active DFGin BLAminus in-in in-in ATP H4N H4N Type1 Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYOA Active DFGin BLAminus in-in in-in ATP KEX KEX Type1 Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSLA Active DFGin BLAminus in-in in-in ADP A9K A9K Type1 Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MOEB Active DFGin BLAminus in-in in-in ADP IHP OQC OQC Type1 Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORJA Active DFGin BLAminus in-in in-in ADP A4Q A4Q IHP Type1 Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CLPB Active DFGin BLAminus in-in in-in 42J 42J 42J 42J 42J Type1 Allosteric Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MOEA Active DFGin BLAminus in-in in-in ADP IHP OQC OQC OQC Type1 Allosteric Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CLPA Active DFGin BLAminus in-in in-in 42J 42J 42J 42J 42J 42J Type1 Type1 Allosteric Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A2 CSK22_HUMAN Casein kinase II subunit alpha' 8Q77A Active DFGin BLAminus in-in in-in LN3 LN3 Allosteric Type1
Homo sapiens CMGC CSNK2A2 CSK22_HUMAN Casein kinase II subunit alpha' 8QBUA Active DFGin BLAminus in-in in-in 42J 3NG Allosteric Type1
Homo sapiens CMGC CSNK2A2 CSK22_HUMAN Casein kinase II subunit alpha' 7AT9A Active DFGin BLAminus in-in in-in 42J 4B0 42J Allosteric Type1 Allosteric
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7O7KA Active DFGin BLAminus in-in in-in 6ZV LI Type1 Allosteric
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7O7KB Active DFGin BLAminus in-in in-in 6ZV LI Type1 Allosteric
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7ZH8A Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7ZH8B Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7ZH8C Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric
Homo sapiens CMGC DYRK1A DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7ZH8D Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 7W5OB Active DFGin BLAminus in-in in-in 6GI Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QAHA Inactive DFGin BLAminus in-out in-in HVB HVB Allosteric Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QALA Active DFGin BLAminus in-in in-in HV2 HV2 Allosteric Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6NBSA Inactive DFGin BLAminus out-out in-in KJ7 KJ4 Allosteric Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 8AOGA Active DFGin BLAminus in-in in-in N29 N29 N29 Allosteric Allosteric Type1
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6G8XA Active DFGin BLAminus out-in in-in EQT EQT Allosteric Type1
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QA1A Inactive DFGin BLAminus out-out in-in HVK HVK HVK HVK HVK HVK HVK Allosteric Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QA4A Inactive DFGin BLAminus out-out in-in HRZ HRZ HRZ HRZ Allosteric Type1 Allosteric Type3
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 5WP1A Inactive DFGin BLAminus out-out in-in B7S BEZ Type1 Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6Q7TA Inactive DFGin BLAminus in-out in-in HOW HOW Type1 Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QAGA Inactive DFGin BLAminus out-out in-in HUH HUH Type1 Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 8AOAA Active DFGin BLAminus out-in in-in N83 OZU Type1 Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 8AODA Active DFGin BLAminus in-in in-in NY0 NYI Type1 Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 8AOHA Active DFGin BLAminus out-in in-in N96 N96 Type1 Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 8AOIA Active DFGin BLAminus out-in in-in NX0 NX0 Type1 Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 7XC1A Active DFGin BLAminus in-in in-in 5ID B8Z Type1 Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 7X4UA Inactive DFGin BLAminus in-out in-in 5ID 8DK BTB Type1 Allosteric Allosteric
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QAQA Inactive DFGin BLAminus out-out in-in HVQ HVQ Type3 Allosteric
Homo sapiens CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 4Z9LA Inactive DFGin ABAminus out-out none-out ANP 880 Allosteric Type1
Homo sapiens CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 8BZPA Inactive DFGin ABAminus in-none out-out SWM C15 Type1 Allosteric
Homo sapiens CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 6EMHA Inactive DFGin ABAminus in-in out-out BGE C15 Type1 Allosteric
Homo sapiens CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 6EMHB Inactive DFGin ABAminus in-in out-out BGE C15 Type1 Allosteric
Homo sapiens CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 6EQ9A Inactive DFGin ABAminus in-out out-out ACP C15 Type1 Allosteric
Homo sapiens CMGC MAPK10 MK10_HUMAN Mitogen-activated protein kinase 10 8BZPB Inactive DFGin ABAminus in-out none-none SWM C15 C15 Type1 Type1 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N68A Inactive DFGin BLBminus in-in none-none 8OK Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3NEWA Inactive DFGin BLBplus in-in none-none 3NE Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH2A Inactive DFGin BLBplus in-in none-out IRG 0OK Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HL7A Inactive DFGin BLBplus in-in none-out I47 I46 Type1 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ROCA Inactive DFGin BLBplus in-out none-out 29A 29B Type1 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HLLA Inactive DFGin BLBplus in-out none-out I45 I46 PO2 Type1 Allosteric Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2RG6A Inactive DFGin BLBplus in-in out-out 287 287 Type1.5_Back Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4E6AA Inactive DFGin None in-in none-none 0O9 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4E6CA Inactive DFGin None in-in none-none 0O8 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N67A Inactive DFGin None in-in none-out 8ON Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4DLIA Inactive DFGin None in-in none-out IRG IRG Allosteric Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH4A Inactive DFGin None in-in none-out IRG 0OL Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3C5UA Inactive DFGin None in-in none-out P41 P41 Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EWQA Inactive DFGin None in-in out-out MWL MWL Type1 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4R3CA Inactive DFGin None in-out none-out 3GF 3GF Type1 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HP2A Inactive DFGin None in-in none-out P36 I46 I46 Type1 Allosteric Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HP5A Inactive DFGin None in-in none-out 52P I46 I46 Type1 Allosteric Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH9A Inactive DFGinter None in-out none-out IRG 0OQ Allosteric Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EHVA Inactive DFGinter None in-none none-out 0SJ 0SJ IRG 0SJ Type3 Allosteric Allosteric Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6QDZA Inactive DFGout BBAminus in-in none-out I46 HYK Allosteric Type2
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6QE1A Inactive DFGout BBAminus in-in none-out I46 HYW Allosteric Type2
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3K3IA Inactive DFGout BBAminus in-in none-out JZJ I46 I46 Type3 Allosteric Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N64A Inactive DFGout None in-in none-out 8OH Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N66A Inactive DFGout None in-in none-out BW1 B96 Allosteric Type2
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH8A Inactive DFGout None in-in none-out IRG 0OP 0OP Allosteric Type3 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2YISA Inactive DFGout None in-in none-out YIS I46 Type2 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2YIWA Inactive DFGout None in-in none-out YIW I46 Type2 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3K3JA Inactive DFGout None in-in none-out F4C I46 Type2 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4E8AA Inactive None None in-in none-none 0OA Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N63A Inactive None None in-in none-out 8OW Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5O8UA Inactive None None in-in none-out 9O5 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5O8VA Inactive None None in-in none-out 9O2 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N65A Inactive None None in-in none-out 8OT 8OT Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4DLJA Inactive None None in-in none-out 6RG 6RG Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH5A Inactive None None in-in none-out IRG 0OM Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH6A Inactive None None in-in none-out IRG 0ON Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH7A Inactive None None in-in none-out IRG 0OO Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH3A Inactive None None in-out none-out NAR IRG Type1 Allosteric
Homo sapiens CMGC MAPK3 MK03_HUMAN Mitogen-activated protein kinase 3 6GESA Active DFGin BLAminus in-in in-in 6H3 EWH Type1 Allosteric
Homo sapiens CMGC MAPK8 MK08_HUMAN Mitogen-activated protein kinase 8 4QTDA Inactive DFGin ABAminus in-out out-out 38Z ANP Type1 Allosteric
Homo sapiens CMGC MAPK8 MK08_HUMAN Mitogen-activated protein kinase 8 3O2MA Active DFGin BLAminus in-in in-in 46A Allosteric
Homo sapiens CMGC MAPK8 MK08_HUMAN Mitogen-activated protein kinase 8 3O2MB Active DFGin BLAminus in-in in-in 46A Allosteric
Homo sapiens OTHER BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 4W9WA Active DFGin BLAminus in-in in-in YDJ YDJ Type1 Allosteric
Homo sapiens OTHER CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 6YA8A Active DFGin BLAminus in-in in-in ADP BEF Type1 Allosteric
Homo sapiens OTHER GAK GAK_HUMAN Cyclin-G-associated kinase 5Y80A Inactive DFGin ABAminus in-in in-out IRE IRE Type1 Allosteric
Homo sapiens OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 4MWIA Inactive DFGin BLBminus in-in out-out PXN Allosteric
Homo sapiens OTHER STK16 STK16_HUMAN Serine/threonine-protein kinase 16 2BUJA Active DFGin BLAminus in-in in-in STU STU Type1 Allosteric
Homo sapiens OTHER TTK TTK_HUMAN Dual specificity protein kinase TTK 7LQDA Inactive DFGin ABAminus out-out out-out YB4 TOE Type1 Allosteric
Homo sapiens OTHER ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 6QASB Active DFGin BLAminus in-in in-in 34W 34W Type1 Allosteric
Homo sapiens OTHER ULK3 ULK3_HUMAN Serine/threonine-protein kinase ULK3 6FDYU Inactive DFGin BLAminus out-out in-in DB8 DB8 Type1 Allosteric
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4MNEH Inactive DFGin BLBplus out-out out-out ACP 573 573 Type1 Type3 Allosteric
Homo sapiens STE MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YZ4A Inactive DFGout None in-out out-out 1E8 Allosteric
Homo sapiens STE MAP2K7 MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 6YG2A Inactive None None in-out out-none 1E8 8E8 Allosteric Type1.5_Front
Homo sapiens STE MAP3K14 M3K14_HUMAN Mitogen-activated protein kinase kinase kinase 14 8YHWD Active DFGin BLAminus in-in in-in AGS PE8 Type1 Allosteric
Homo sapiens STE STK4 STK4_HUMAN Serine/threonine-protein kinase 4 6YATA Active DFGin BLAminus in-in in-in 3FX OJ5 Allosteric Type1
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6SZMA Inactive DFGin BLAminus in-out in-in M2Z M2Z M2Z Allosteric Allosteric Type1
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7QB Inactive DFGin BLAminus in-out in-in XJM LU8 XJM Allosteric Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7BB Inactive DFGin BLAminus in-out in-in LU8 XH7 Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7CB Inactive DFGin BLAminus in-out in-in LU8 T5Y Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7DB Inactive DFGin BLAminus in-out in-in LU8 XHD Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7EB Inactive DFGin BLAminus in-out in-in LU8 XEA Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7KB Inactive DFGin BLAminus in-out in-in LU8 XEJ Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7MB Inactive DFGin BLAminus in-out in-in LU8 HVK Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7NB Inactive DFGin BLAminus in-out in-in LU8 2AI Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7SB Inactive DFGin BLAminus in-out in-in LU8 09V Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7VB Inactive DFGin BLAminus in-out in-in LU8 XH1 Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7XB Inactive DFGin BLAminus in-out in-in LU8 LGA Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7ZB Inactive DFGin BLAminus in-out in-in LU8 BYZ Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S82B Inactive DFGin BLAminus in-out in-in LU8 LAC Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S86B Inactive DFGin BLAminus in-out in-in LU8 XK7 Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S87B Inactive DFGin BLAminus in-out in-in LU8 XKD Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S88B Inactive DFGin BLAminus in-out in-in LU8 XKS Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S8AB Inactive DFGin BLAminus in-out in-in LU8 XKY Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S75B Inactive DFGin BLAminus in-out in-in LU8 HUH HUH Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S79A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7AB Inactive DFGin BLAminus in-out in-in LU8 T5V T5V Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7EA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7FA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7FB Inactive DFGin BLAminus in-out in-in LU8 XH4 XH4 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7GA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7OA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7QA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7UA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7UB Inactive DFGin BLAminus in-out in-in LU8 XGY XGY Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7VA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7WA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7YA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S80A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S80B Inactive DFGin BLAminus in-out in-in LU8 XGM XGM Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S82A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S87A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S88A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S9KA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6SRHB Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 6Z36A Inactive DFGin BLAminus in-out in-in Q5Z Q5Z Q5Z Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S77A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 BAQ Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7DA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XHD Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7JA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XHG Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7KA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XEJ Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7LA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XHJ Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7MA Inactive DFGin BLAminus in-out in-in LU8 LU8 HVK HVK Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7NA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 2AI Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7PA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 V1L Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7SA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 09V Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7TB Inactive DFGin BLAminus in-out in-in LU8 XGJ XGJ XGJ Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7XA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 LGA Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S86A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XK7 Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S89A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XKV Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S8AA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XKY Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S8BB Inactive DFGin BLAminus in-out in-in LU8 XFV XFV XFV Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S75A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HUH HUH Type1 Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7AA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 T5V T5V Type1 Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7BA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XH7 XH7 Type1 Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7HA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HVB HVB Type1 Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7ZA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 BYZ BYZ Type1 Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S81B Inactive DFGin BLAminus in-out in-in LU8 XJV XJV XJV XJV Type1 Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7CA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 T5Y T5Y T5Y Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7IA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HV2 HV2 HV2 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7TA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XGJ XGJ XGJ Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7YB Inactive DFGin BLAminus in-out in-in LU8 XJP XJP XJP XJP XJP Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7RB Inactive DFGin BLAminus in-out in-in LU8 XGS XGS XGS XGS XGS XGS Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S85A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XK4 XK4 XK4 XK4 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S8BA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XFV XFV XFV XFV Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7RA Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XGS XGS XGS XGS XGS Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7IB Inactive DFGin BLAminus in-out in-in LU8 HV2 HV2 HV2 HV2 HV2 HV2 HV2 HV2 HV2 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S78A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XGV XGV XGV Type1 Allosteric Allosteric Allosteric Allosteric Type1
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S81A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XJV XJV Type1 Allosteric Allosteric Allosteric Type1
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S76A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 02A 02A Type1 Allosteric Allosteric Allosteric Type1.5_Back
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7LB Inactive DFGin BLAminus in-out in-in LU8 XHJ XHJ XHJ XHJ Type1 Allosteric Allosteric Allosteric Type3
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S84A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XK1 Type1 Allosteric Allosteric Type1
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S83A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XJY Type1 Allosteric Allosteric Type3
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S85B Inactive DFGin BLAminus in-out in-in LU8 XK4 XK4 XK4 Type1 Type1 Allosteric Allosteric
Homo sapiens TKL BMPR2 BMPR2_HUMAN Bone morphogenetic protein receptor type-2 6UNPA Active DFGin BLAminus in-in in-in ADP ADP Type1 Allosteric
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6P7GB Inactive DFGout BBAminus in-in out-out E7M NHE Type2 Allosteric
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 7C2WA Inactive DFGin BLAminus in-out in-in YTH FJ9 Allosteric Type1
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 7C2WB Inactive DFGin BLAminus in-out in-in YTH FJ9 Allosteric Type1
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 7C2WC Inactive DFGin BLAminus in-out in-in YTH FJ9 Allosteric Type1
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 7C2WD Inactive DFGin BLAminus in-out in-in YTH FJ9 Allosteric Type1
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 4YO6D Inactive DFGin BLAminus in-out in-in 4GD 4GD Type1 Allosteric
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6TIAA Inactive DFGin BLAminus in-out in-in ND2 ND2 ND2 ND2 Type1 Allosteric Allosteric Allosteric
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 6TIAB Inactive DFGin BLAminus in-out in-in ND2 ND2 ND2 ND2 Type1 Allosteric Allosteric Allosteric
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2HZ4A Inactive DFGin BLAminus in-out in-in 4ST Allosteric
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2HZ4C Active DFGin BLAminus in-in in-in 4ST Allosteric
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GB Active DFGin BLAminus in-in in-in STI 1N1 Allosteric Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8SSNB Inactive DFGin BLBplus out-out none-none AY7 SKI Allosteric Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8SSNA Inactive DFGin BLBplus out-out out-none AY7 SKI Allosteric Type1.5_Back
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GA Inactive DFGinter None in-out out-in STI 1N1 Allosteric Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GC Inactive DFGinter None in-none out-in STI 1N1 Allosteric Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 5HU9A Inactive DFGout BBAminus in-in out-out 66K 66K Type2 Allosteric
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3PYYA Inactive DFGout BBAminus in-in out-in STI 3YY Type2 Allosteric
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3PYYB Inactive DFGout BBAminus in-in none-out STI 3YY Type2 Allosteric
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6NPEA Inactive DFGout BBAminus in-in out-in STI KWD Type2 Allosteric
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6NPEB Inactive DFGout BBAminus in-in none-in STI KWD Type2 Allosteric
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6NPUA Inactive DFGout BBAminus in-in out-in STI KWV Type2 Allosteric
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6NPUB Inactive DFGout BBAminus in-in none-in STI KWV Type2 Allosteric
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6NPVA Inactive DFGout BBAminus in-in out-in STI KWP Type2 Allosteric
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6NPVB Inactive DFGout BBAminus in-in none-in STI KWP Type2 Allosteric
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 5MO4A Inactive DFGout None in-in none-out NIL AY7 Type2 Allosteric
Homo sapiens TYR ABL2 ABL2_HUMAN Tyrosine-protein kinase ABL2 2XYNB None DFGin BLAminus in-none in-in VX6 VX6 VX6 Type1 Allosteric Allosteric
Homo sapiens TYR ABL2 ABL2_HUMAN Tyrosine-protein kinase ABL2 2XYNC None DFGin BLAminus in-none in-in VX6 VX6 VX6 Type1 Allosteric Allosteric
Homo sapiens TYR ABL2 ABL2_HUMAN Tyrosine-protein kinase ABL2 3GVUA Inactive DFGout BBAminus in-in out-in STI STI Type2 Allosteric
Homo sapiens TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 4TT7A Inactive DFGin ABAminus in-in out-out COM COM Allosteric Allosteric
Homo sapiens TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 7JY4A Inactive DFGin ABAminus in-out out-out W47 W47 Allosteric Type1
Homo sapiens TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 4CNHB Inactive DFGin ABAminus in-in out-out 3U9 3U9 Type1 Allosteric
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 3PJ1A Inactive DFGin BLAplus in-in none-out LHL LHL Type1 Allosteric
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 8EJBA Inactive DFGin BLBplus out-out out-out WKC PD Type1 Allosteric
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6X3NA Inactive DFGin BLBplus out-out none-in ULV 5WE Type1 Allosteric
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5FBOA Inactive DFGin BLBplus out-out none-out 5WH 5WE Type1.5_Back Allosteric
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 8FLNA Inactive DFGin BLBplus out-out out-out Y7W BTB Type1.5_Front Allosteric
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5FBNC Inactive DFGin BLBplus out-out out-out 5WF 5WE Type1.5_Front Allosteric
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6X3OA Inactive DFGin BLBplus out-out out-out ULY 5WE Type1.5_Front Allosteric
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6X3OB Inactive DFGin BLBplus out-out out-out ULY 5WE Type1.5_Front Allosteric
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 8FLLA Inactive DFGin BLBplus out-none out-out Y7W BTB Type1.5_Front Allosteric
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 5FBND Inactive DFGin BLBplus out-out out-in 5WF 5WE 5WE 5WE Type1.5_Front Allosteric Allosteric Allosteric
Homo sapiens TYR BTK BTK_HUMAN Tyrosine-protein kinase BTK 6X3PA Inactive DFGin BLBplus out-out out-out UM4 UM4 BTB Type1.5_Front Allosteric Type1
Homo sapiens TYR CSF1R CSF1R_HUMAN Macrophage colony-stimulating factor 1 receptor 8CGCA Inactive DFGout BBAminus in-in out-in LMR UIK Allosteric Type1
Homo sapiens TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 3ZOSA Inactive DFGout BBAminus in-in out-in 0LI 0LI Type2 Allosteric
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV4A Active DFGin BLAminus in-in in-in PE5 MWU Allosteric Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV6A Active DFGin BLAminus in-in in-in PE5 N86 Allosteric Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV7A Active DFGin BLAminus in-in in-in PE5 N8O Allosteric Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV8A Active DFGin BLAminus in-in in-in PE5 N99 Allosteric Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV9A Active DFGin BLAminus in-in in-in PE5 N9L Allosteric Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV1A Active DFGin BLAminus in-in in-in PE5 N6N Allosteric Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV3A Active DFGin BLAminus in-in in-in PE5 MWU Allosteric Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8HV5A Active DFGin BLAminus in-in in-in PE5 N7C Allosteric Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6JX0A Active DFGin BLAminus in-in in-in YY3 YY3 Type1 Allosteric
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4G5JA Active DFGin BLAminus in-in in-in 0WN 0WM 0WM Type1 Allosteric Allosteric
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5X2AA Inactive DFGin BLBtrans out-out out-in 7XO ANP Type1 Allosteric
Homo sapiens TYR EPHA3 EPHA3_HUMAN Ephrin type-A receptor 3 6IN0A Inactive DFGin BLAminus in-out in-in O4B O4B Type3 Allosteric
Homo sapiens TYR FES FES_HUMAN Tyrosine-protein kinase Fes/Fps 3CBLA Active DFGin BLAminus in-in in-in STU STU STU Type1 Allosteric Allosteric
Homo sapiens TYR FES FES_HUMAN Tyrosine-protein kinase Fes/Fps 3CD3A Active DFGin BLAminus in-in in-in STU STU STU Type1 Allosteric Allosteric
Homo sapiens TYR FGFR2 FGFR2_HUMAN Fibroblast growth factor receptor 2 8SWEA Active DFGin BLAminus in-in in-in GSH WXQ Allosteric Type1
Homo sapiens TYR FGFR3 FGFR3_HUMAN Fibroblast growth factor receptor 3 8UDTA Inactive DFGin BLAplus in-out out-out MLT MLT WGF Allosteric Allosteric Type1.5_Front
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0A Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0B Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0C Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0D Inactive DFGout None in-out out-in CCX CCX Type3 Allosteric
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5HEZA Inactive DFGin ABAminus in-in in-out 1M3 1M3 Allosteric Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5HEZB Inactive DFGin ABAminus in-in in-out 1M3 1M3 Allosteric Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5HEZD Inactive DFGin ABAminus in-in in-out 1M3 1M3 Allosteric Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5HEZC Inactive DFGin ABAminus in-in in-out 1M3 1M3 Type1 Allosteric
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 4IWDA Inactive DFGin ABAminus in-in in-in AME 1JC Allosteric Type1
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 3Q6UA Inactive DFGin BLBminus in-out none-in AME Allosteric
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6DKGA Inactive DFGout BBAminus in-out none-in 22L GO7 Allosteric Type2
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6DKIA Inactive DFGout BBAminus in-out out-in 22L GOD Allosteric Type2
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D1ZA Inactive DFGout BBAminus in-out out-in FQD FQM Allosteric Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D20A Inactive DFGout None out-out out-in FQD FQG Allosteric Type3
Homo sapiens TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 4OLIA Active DFGin BLAminus in-in in-in 2TT 2TT Allosteric Type1
Methanocaldococcus jannaschii OTHER BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 2VWBA Inactive DFGin None in-in in-none ANP Allosteric
Methanocaldococcus jannaschii OTHER BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 2VWBB Inactive DFGin None in-in in-none ANP Allosteric
Methanocaldococcus jannaschii OTHER BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3EN9A Inactive DFGin None in-in in-none TBR Allosteric
Methanocaldococcus jannaschii OTHER BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3EN9B Inactive DFGin None in-in in-none TBR Allosteric
Methanocaldococcus jannaschii OTHER BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3ENHA Inactive DFGin None in-in in-none TBR TBR TBR Allosteric Allosteric Allosteric
Methanocaldococcus jannaschii OTHER BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3ENHB Inactive DFGin None in-in in-none TBR TBR TBR TBR Allosteric Allosteric Allosteric Allosteric
Miscanthus lutarioriparius TKL RIPK A0A811MC32_9POAL Protein kinase domain-containing protein 8HOAA Inactive DFGin BLBplus out-none none-out ATP HX2 Type1 Allosteric
Monosiga brevicollis TYR RTKC8 A9VBW0_MONBE TK/RTKC protein kinase 8E4TA Inactive DFGin BLAminus in-in in-out STU STU Type1 Allosteric
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1REKA Active DFGin BLAminus in-in in-in B8L PTL Type1 Allosteric
Mus musculus CAMK DAPK2 DAPK2_MOUSE Death-associated protein kinase 2 2YA9A Active DFGin BLAminus in-in in-in D1D Allosteric
Mus musculus CAMK DAPK2 DAPK2_MOUSE Death-associated protein kinase 2 2YA9B Active DFGin BLAminus in-in in-in D1D Allosteric
Mus musculus CAMK RPS6KA3 KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 5O1SA None DFGin BLAminus in-in in-none 9HB 9HB Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8VA Inactive DFGin BLBminus in-in none-out SLV Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8WA Inactive DFGin BLBminus in-in out-out JND Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8XA Inactive DFGin BLBminus in-in out-out SLY Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R93A Inactive DFGin BLBminus in-in none-out SOJ Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R94A Inactive DFGin BLBminus in-in none-out SOV Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R95A Inactive DFGin BLBminus in-in none-out SQ4 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R96A Inactive DFGin BLBminus in-in none-out SQ7 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R98A Inactive DFGin BLBminus in-in out-out SQG Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9AA Inactive DFGin BLBminus in-in out-out SQM Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9BA Inactive DFGin BLBminus in-in none-out JGM Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9GA Inactive DFGin BLBminus in-in out-out RGY Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9HA Inactive DFGin BLBminus in-in none-out SQV Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9OA Inactive DFGin BLBminus in-in out-out 54F Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9SA Inactive DFGin BLBminus in-in out-out A9B Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9TA Inactive DFGin BLBminus in-in out-out 6T5 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9VA Inactive DFGin BLBminus in-in out-out SSY Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9XA Inactive DFGin BLBminus in-in out-out NZ4 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9ZA Inactive DFGin BLBminus in-in out-out AYS Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA3A Inactive DFGin BLBminus in-in out-out SVD Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA4A Inactive DFGin BLBminus in-in out-out SVG Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA5A Inactive DFGin BLBminus in-in out-out SVJ Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOIA Inactive DFGin BLBminus in-in none-out LOK Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SO1A Inactive DFGin BLBminus in-in none-out LO5 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SO2A Inactive DFGin BLBminus in-in none-out JGG Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SO4A Inactive DFGin BLBminus in-in none-out LO8 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SODA Inactive DFGin BLBminus in-none none-out LOE Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOTA Inactive DFGin BLBminus in-in none-out LOQ Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9MA Inactive DFGin BLBminus in-in none-out A7K A7K Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 7Z9TBBB Inactive DFGin BLBminus out-out out-out 87B ATP Type3 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7ZA Inactive DFGin BLBplus in-in none-out OG2 SB4 Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y80A Inactive DFGin BLBplus in-in out-out OFZ SB4 Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y85A Inactive DFGin BLBplus in-in none-out OG8 SB4 Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7WA Inactive DFGin BLBplus in-in none-out SB4 OFW Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7XA Inactive DFGin BLBplus in-in none-out SB4 OFQ Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y81A Inactive DFGin BLBplus in-in none-out SB4 OG5 Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y82A Inactive DFGin BLBplus in-in out-out SB4 308 Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6YCWA Inactive DFGin BLBplus in-in none-out SB4 OL8 Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOVA Inactive DFGin BLBplus in-in none-out SB4 LOT LOW Type1 Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SP9A Inactive DFGin BLBplus in-in out-out SB4 LOT LOT Type1 Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7YA Inactive DFGin BLBplus in-in none-out SB4 OFQ LOT LOT Type1 Allosteric Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SPLA Inactive DFGin BLBplus in-in out-out SB4 LOW LOW LOW Type1 Allosteric Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOUA Inactive DFGin None in-in out-out LPZ LPZ Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6YCUA Inactive DFGin None in-in out-out SB4 OKZ Type1 Allosteric
Mus musculus OTHER AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ8A Active DFGin BLAminus in-in in-in 5QI PG6 Type1 Allosteric
Mus musculus OTHER AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ8B Active DFGin BLAminus in-in in-in YFV PG6 Type1 Allosteric
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL3A Inactive DFGin BLBplus out-out out-in 31J ADP Allosteric Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL3B Inactive DFGin BLBplus out-out out-in 31J ADP Allosteric Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4A Inactive DFGin BLBplus out-out out-in 31K ADP Allosteric Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5A Inactive DFGin BLBplus out-out out-in 31L ADP PEU Allosteric Type1 Allosteric
Mus musculus OTHER POMK SG196_MOUSE Protein O-mannose kinase 5GZ9A Inactive DFGin ABAminus none-none in-out ANP MAN Type1 Allosteric
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3K5VA Inactive DFGout BBAminus in-in out-in STJ STI Allosteric Type2
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3K5VB Inactive DFGout BBAminus in-in out-in STJ STI Allosteric Type2
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 6HD4A Inactive DFGout BBAminus in-in out-in FYW STI Allosteric Type2
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 6HD4B Inactive DFGout BBAminus in-in out-in FYW STI Allosteric Type2
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 6HD6A Inactive DFGout BBAminus in-in out-in FYH STI Allosteric Type2
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3MS9A Inactive DFGout BBAminus in-in out-in STI MS9 Type2 Allosteric
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3MS9B Inactive DFGout BBAminus in-in out-in STI MS9 Type2 Allosteric
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3MSSA Inactive DFGout BBAminus in-in out-in STI MS7 Type2 Allosteric
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3MSSB Inactive DFGout BBAminus in-in out-in STI MS7 Type2 Allosteric
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3MSSC Inactive DFGout BBAminus in-in out-in STI MS7 Type2 Allosteric
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3MSSD Inactive DFGout BBAminus in-in out-in STI MS7 Type2 Allosteric
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 7T6FA Inactive DFGin None in-out in-in ADN ADP Allosteric Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 7T6FB Inactive DFGin None in-out in-in ADN ADP Allosteric Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 8EWYA Inactive None None in-none in-in ADN ADP Allosteric Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 8EWYB Inactive None None in-none in-in ADN ADP Allosteric Type1
Mycobacterium tuberculosis OTHER PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 6B2QA Inactive DFGin BLAminus in-in in-out CJJ 0BD Type1 Allosteric
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3OROA Inactive DFGin BLBminus in-out out-out AGS NHE Type1 Allosteric
Mycobacterium tuberculosis OTHER PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 7Q52AAA Inactive DFGin ABAminus out-out in-in FE 8ZC Allosteric Type1
Rattus norvegicus AGC CDC42BPA MRCKA_RAT Serine/threonine-protein kinase MRCK alpha 4AW2A Active DFGin BLAminus in-in in-in 22E Allosteric
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 6E4TA Inactive DFGin ABAminus out-in in-out HTV STU Allosteric Type1
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 4QFRA Inactive DFGin ABAminus in-in in-out STU 32J Type1 Allosteric
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 4QFSA Inactive DFGin ABAminus in-in in-out STU 32H Type1 Allosteric
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 6E4UA Inactive DFGin ABAminus in-in in-out STU HU7 Type1 Allosteric
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 6E4WA Inactive DFGin ABAminus out-in in-out STU HUG Type1 Allosteric
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 5UFUA Inactive DFGin BLAminus in-in in-out STU 85V Type1 Allosteric
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 5KQ5A Inactive DFGin None in-in in-out STU 6VT Type1 Allosteric
Rattus norvegicus CK1 CSNK1D KC1D_RAT Casein kinase I isoform delta 1CKJA Active DFGin BLAminus in-in in-in WO4 WO4 Allosteric Allosteric
Rattus norvegicus CK1 CSNK1D KC1D_RAT Casein kinase I isoform delta 1CKJB Active DFGin BLAminus in-in in-in WO4 WO4 WO4 Allosteric Allosteric Allosteric
Saccharomyces cerevisiae OTHER CDC7 CDC7_YEAST Cell division control protein 7 7PT78 Inactive DFGin ABAminus in-out in-in ADP BEF Type1 Allosteric
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ0A None DFGin BLAminus in-in in-none ADP QUE Type1 Allosteric
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ0B None DFGin BLAminus in-in in-none ADP QUE Type1 Allosteric
Salmo salar CMGC P38A A9UJZ9_SALSA mitogen-activated protein kinase 3OHTA Inactive DFGout None in-in none-none 1N1 1N1 Type1.5_Back Allosteric
Salmo salar CMGC P38A A9UJZ9_SALSA mitogen-activated protein kinase 3OHTB Inactive DFGout None in-in none-none 1N1 1N1 Type1.5_Back Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1OA Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1OB Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1OC Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1OD Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1PA Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1PB Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1PC Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1PD Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M11a Active DFGin BLAminus in-in in-none 25A B49 Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M11b Active DFGin BLAminus in-in in-none 25A B49 Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M12b Active DFGin BLAminus in-in in-none 25L J60 Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DSYa Active DFGin BLAminus in-in in-none 25A HFX Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DSYb Active DFGin BLAminus in-in in-none 25A HFX Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DTSa Active DFGin BLAminus in-in in-none 25A 27K Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DTSb Active DFGin BLAminus in-in in-none 25A 27K Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7ELWa Active DFGin BLAminus in-in in-none 25L MYC Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7ELWb Active DFGin BLAminus in-in in-none 25L MYC Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M12a Active DFGin BLAminus in-in in-none J60 25L Type1 Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M13a Active DFGin BLAminus in-in in-none BWC 25L Type1 Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M13b Active DFGin BLAminus in-in in-none BWC 25L Type1 Allosteric

Non-Human protein kinases in complex with Allosteric ligands

Total number of genes: 29
Total number of chains: 164
Spatial Label Dihedral Label AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Total
DFGin BLAminus 28 4 2 0 0 0 0 2 1 17 54
DFGin BLAplus 0 0 0 0 0 0 0 0 0 0 0
DFGin ABAminus 2 6 0 0 0 0 0 0 0 11 19
DFGin BLBminus 0 5 0 29 0 0 0 0 0 2 36
DFGin BLBplus 0 0 0 12 0 0 0 1 2 4 19
DFGin BLBtrans 0 0 0 0 0 0 0 0 0 0 0
DFGin None 0 1 0 2 0 0 0 0 3 7 13
DFGinter BABtrans 0 0 0 0 0 0 0 0 0 0 0
DFGinter None 0 0 0 0 0 0 0 0 0 0 0
DFGout BBAminus 0 0 0 0 0 0 0 0 11 0 11
DFGout None 0 0 0 2 0 0 0 0 0 0 2
None None 0 0 0 0 0 0 0 8 2 0 10
Total - 30 16 2 45 0 0 0 11 19 41 164
Download as tsv
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment


Organism Group Gene UniprotID Protein PDB Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActloopCT Ligand Type
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZTC Inactive DFGin BLBminus out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUB Inactive DFGin BLBminus out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUC Inactive DFGin BLBminus out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUD Inactive DFGin BLBminus out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZTD Inactive DFGin BLBminus out-out out-out CPS CPS CPS Type1 Allosteric Allosteric
Arabidopsis thaliana OTHER BIR2 BIR2_ARATH Inactive LRR receptor-like serine/threonine-protein kinase BIR2 4L68A Inactive DFGin BLBminus out-out out-in PDO Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5TA Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5TD Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5TI Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5TJ Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5TM Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5UC Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J5VC Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Arabidopsis thaliana TKL PBL2 PBL2_ARATH Probable serine/threonine-protein kinase PBL2 6J6IA Inactive None None none-none none-out U5P U5P Allosteric Allosteric
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2GNHA Inactive DFGin ABAminus in-in in-in H52 H52 Type1 Allosteric
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2VO7A Active DFGin BLAminus in-in in-in M05 M05 Allosteric Type1
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 1Q8UA Active DFGin BLAminus in-in in-in H52 H52 Type1 Allosteric
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 3BWJA Active DFGin BLAminus in-in in-in ARX ARX Type1 Allosteric
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 4Z83E Active DFGin BLAminus in-in in-in 4L7 4L7 Type1 Allosteric
Bos taurus AGC PRKACA KAPCA_BOVIN cAMP-dependent protein kinase catalytic subunit alpha 2VO0A Active DFGin BLAminus in-in in-in M03 M03 Type1 Allosteric
Bos taurus TYR BTK Q3ZC95_BOVIN Tyrosine-protein kinase 4Y95B Inactive DFGin BLBplus out-out out-out 746 PE4 Type1 Allosteric
Bos taurus TYR BTK Q3ZC95_BOVIN Tyrosine-protein kinase 4Y95C Inactive DFGin BLBplus out-out out-out 746 PE4 Type1 Allosteric
Caenorhabditis elegans CAMK TWITCHIN UNC22_CAEEL Twitchin 3UTOB Inactive DFGin ABAminus out-out in-out P33 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6I2BA Inactive DFGin ABAminus in-in in-in 9LQ 9LQ Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3NA Active DFGin BLAminus in-in in-in 152 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N1GA Active DFGin BLAminus in-in in-in 8G5 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N1NA Active DFGin BLAminus in-in in-in 8G8 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3IA Active DFGin BLAminus in-in in-in BJQ Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3KA Active DFGin BLAminus in-in in-in GGB Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3RA Active DFGin BLAminus in-in in-in CDT Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6Z08A Active DFGin BLAminus in-in in-in NPO Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N37A Active DFGin BLAminus in-in in-in 8JT 8JT Allosteric Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3GA Active DFGin BLAminus in-in in-in 8KB 8KB Allosteric Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3TA Active DFGin BLAminus in-in in-in 8K2 8K2 Allosteric Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 7AXVA Active DFGin BLAminus in-in in-in S95 S95 Allosteric Type1
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3OA Active DFGin BLAminus in-in in-in 5AO 5AO 5AO Allosteric Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5M0LA Active DFGin BLAminus in-in in-in 7CT 7CT Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5MHIA Active DFGin BLAminus in-in in-in 7N9 7N9 Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N1KA Active DFGin BLAminus in-in in-in 489 489 Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N32A Active DFGin BLAminus in-in in-in 8K5 8K5 Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3FA Active DFGin BLAminus in-in in-in 463 463 Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 5N3QA Active DFGin BLAminus in-in in-in 3AB 3AB Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6SNXA Active DFGin BLAminus in-in in-in UNU UNU Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6YOTA Active DFGin BLAminus in-in in-in P4W P4W Type1 Allosteric
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6ZN0A Active DFGin BLAminus in-in in-in NTN NTN Type1 Allosteric
Danio rerio OTHER POMK SG196_DANRE Protein O-mannose kinase 5GZAA Inactive DFGin None none-none in-out ADP ZZ1 Type1 Allosteric
Dictyostelium discoideum TKL ROCO4 ROCO4_DICDI Probable serine/threonine-protein kinase roco4 4F1TA Inactive DFGin BLAminus in-in in-out H52 H52 Type1 Allosteric
Dictyostelium discoideum TKL ROCO4 ROCO4_DICDI Probable serine/threonine-protein kinase roco4 4F1MA Inactive DFGin BLAminus in-in in-out ACP BTB Type1 Allosteric
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 2QLQA Inactive DFGin None none-none none-none SR2 SR2 Type1 Allosteric
Methanocaldococcus jannaschii OTHER BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 2VWBA Inactive DFGin None in-in in-none ANP Allosteric
Methanocaldococcus jannaschii OTHER BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 2VWBB Inactive DFGin None in-in in-none ANP Allosteric
Methanocaldococcus jannaschii OTHER BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3EN9A Inactive DFGin None in-in in-none TBR Allosteric
Methanocaldococcus jannaschii OTHER BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3EN9B Inactive DFGin None in-in in-none TBR Allosteric
Methanocaldococcus jannaschii OTHER BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3ENHA Inactive DFGin None in-in in-none TBR TBR TBR Allosteric Allosteric Allosteric
Methanocaldococcus jannaschii OTHER BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3ENHB Inactive DFGin None in-in in-none TBR TBR TBR TBR Allosteric Allosteric Allosteric Allosteric
Miscanthus lutarioriparius TKL RIPK A0A811MC32_9POAL Protein kinase domain-containing protein 8HOAA Inactive DFGin BLBplus out-none none-out ATP HX2 Type1 Allosteric
Monosiga brevicollis TYR RTKC8 A9VBW0_MONBE TK/RTKC protein kinase 8E4TA Inactive DFGin BLAminus in-in in-out STU STU Type1 Allosteric
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1REKA Active DFGin BLAminus in-in in-in B8L PTL Type1 Allosteric
Mus musculus CAMK DAPK2 DAPK2_MOUSE Death-associated protein kinase 2 2YA9A Active DFGin BLAminus in-in in-in D1D Allosteric
Mus musculus CAMK DAPK2 DAPK2_MOUSE Death-associated protein kinase 2 2YA9B Active DFGin BLAminus in-in in-in D1D Allosteric
Mus musculus CAMK RPS6KA3 KS6A3_MOUSE Ribosomal protein S6 kinase alpha-3 5O1SA None DFGin BLAminus in-in in-none 9HB 9HB Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8VA Inactive DFGin BLBminus in-in none-out SLV Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8WA Inactive DFGin BLBminus in-in out-out JND Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8XA Inactive DFGin BLBminus in-in out-out SLY Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R93A Inactive DFGin BLBminus in-in none-out SOJ Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R94A Inactive DFGin BLBminus in-in none-out SOV Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R95A Inactive DFGin BLBminus in-in none-out SQ4 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R96A Inactive DFGin BLBminus in-in none-out SQ7 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R98A Inactive DFGin BLBminus in-in out-out SQG Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9AA Inactive DFGin BLBminus in-in out-out SQM Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9BA Inactive DFGin BLBminus in-in none-out JGM Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9GA Inactive DFGin BLBminus in-in out-out RGY Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9HA Inactive DFGin BLBminus in-in none-out SQV Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9OA Inactive DFGin BLBminus in-in out-out 54F Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9SA Inactive DFGin BLBminus in-in out-out A9B Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9TA Inactive DFGin BLBminus in-in out-out 6T5 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9VA Inactive DFGin BLBminus in-in out-out SSY Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9XA Inactive DFGin BLBminus in-in out-out NZ4 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9ZA Inactive DFGin BLBminus in-in out-out AYS Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA3A Inactive DFGin BLBminus in-in out-out SVD Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA4A Inactive DFGin BLBminus in-in out-out SVG Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA5A Inactive DFGin BLBminus in-in out-out SVJ Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOIA Inactive DFGin BLBminus in-in none-out LOK Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SO1A Inactive DFGin BLBminus in-in none-out LO5 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SO2A Inactive DFGin BLBminus in-in none-out JGG Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SO4A Inactive DFGin BLBminus in-in none-out LO8 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SODA Inactive DFGin BLBminus in-none none-out LOE Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOTA Inactive DFGin BLBminus in-in none-out LOQ Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9MA Inactive DFGin BLBminus in-in none-out A7K A7K Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 7Z9TBBB Inactive DFGin BLBminus out-out out-out 87B ATP Type3 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7ZA Inactive DFGin BLBplus in-in none-out OG2 SB4 Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y80A Inactive DFGin BLBplus in-in out-out OFZ SB4 Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y85A Inactive DFGin BLBplus in-in none-out OG8 SB4 Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7WA Inactive DFGin BLBplus in-in none-out SB4 OFW Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7XA Inactive DFGin BLBplus in-in none-out SB4 OFQ Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y81A Inactive DFGin BLBplus in-in none-out SB4 OG5 Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y82A Inactive DFGin BLBplus in-in out-out SB4 308 Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6YCWA Inactive DFGin BLBplus in-in none-out SB4 OL8 Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOVA Inactive DFGin BLBplus in-in none-out SB4 LOT LOW Type1 Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SP9A Inactive DFGin BLBplus in-in out-out SB4 LOT LOT Type1 Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7YA Inactive DFGin BLBplus in-in none-out SB4 OFQ LOT LOT Type1 Allosteric Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SPLA Inactive DFGin BLBplus in-in out-out SB4 LOW LOW LOW Type1 Allosteric Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOUA Inactive DFGin None in-in out-out LPZ LPZ Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6YCUA Inactive DFGin None in-in out-out SB4 OKZ Type1 Allosteric
Mus musculus OTHER AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ8A Active DFGin BLAminus in-in in-in 5QI PG6 Type1 Allosteric
Mus musculus OTHER AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ8B Active DFGin BLAminus in-in in-in YFV PG6 Type1 Allosteric
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL3A Inactive DFGin BLBplus out-out out-in 31J ADP Allosteric Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL3B Inactive DFGin BLBplus out-out out-in 31J ADP Allosteric Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4A Inactive DFGin BLBplus out-out out-in 31K ADP Allosteric Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5A Inactive DFGin BLBplus out-out out-in 31L ADP PEU Allosteric Type1 Allosteric
Mus musculus OTHER POMK SG196_MOUSE Protein O-mannose kinase 5GZ9A Inactive DFGin ABAminus none-none in-out ANP MAN Type1 Allosteric
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3K5VA Inactive DFGout BBAminus in-in out-in STJ STI Allosteric Type2
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3K5VB Inactive DFGout BBAminus in-in out-in STJ STI Allosteric Type2
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 6HD4A Inactive DFGout BBAminus in-in out-in FYW STI Allosteric Type2
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 6HD4B Inactive DFGout BBAminus in-in out-in FYW STI Allosteric Type2
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 6HD6A Inactive DFGout BBAminus in-in out-in FYH STI Allosteric Type2
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3MS9A Inactive DFGout BBAminus in-in out-in STI MS9 Type2 Allosteric
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3MS9B Inactive DFGout BBAminus in-in out-in STI MS9 Type2 Allosteric
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3MSSA Inactive DFGout BBAminus in-in out-in STI MS7 Type2 Allosteric
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3MSSB Inactive DFGout BBAminus in-in out-in STI MS7 Type2 Allosteric
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3MSSC Inactive DFGout BBAminus in-in out-in STI MS7 Type2 Allosteric
Mus musculus TYR ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3MSSD Inactive DFGout BBAminus in-in out-in STI MS7 Type2 Allosteric
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 7T6FA Inactive DFGin None in-out in-in ADN ADP Allosteric Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 7T6FB Inactive DFGin None in-out in-in ADN ADP Allosteric Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 8EWYA Inactive None None in-none in-in ADN ADP Allosteric Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 8EWYB Inactive None None in-none in-in ADN ADP Allosteric Type1
Mycobacterium tuberculosis OTHER PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 6B2QA Inactive DFGin BLAminus in-in in-out CJJ 0BD Type1 Allosteric
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3OROA Inactive DFGin BLBminus in-out out-out AGS NHE Type1 Allosteric
Mycobacterium tuberculosis OTHER PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 7Q52AAA Inactive DFGin ABAminus out-out in-in FE 8ZC Allosteric Type1
Rattus norvegicus AGC CDC42BPA MRCKA_RAT Serine/threonine-protein kinase MRCK alpha 4AW2A Active DFGin BLAminus in-in in-in 22E Allosteric
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 6E4TA Inactive DFGin ABAminus out-in in-out HTV STU Allosteric Type1
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 4QFRA Inactive DFGin ABAminus in-in in-out STU 32J Type1 Allosteric
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 4QFSA Inactive DFGin ABAminus in-in in-out STU 32H Type1 Allosteric
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 6E4UA Inactive DFGin ABAminus in-in in-out STU HU7 Type1 Allosteric
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 6E4WA Inactive DFGin ABAminus out-in in-out STU HUG Type1 Allosteric
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 5UFUA Inactive DFGin BLAminus in-in in-out STU 85V Type1 Allosteric
Rattus norvegicus CAMK PRKAA1 AAPK1_RAT 5'-AMP-activated protein kinase catalytic subunit alpha-1 5KQ5A Inactive DFGin None in-in in-out STU 6VT Type1 Allosteric
Rattus norvegicus CK1 CSNK1D KC1D_RAT Casein kinase I isoform delta 1CKJA Active DFGin BLAminus in-in in-in WO4 WO4 Allosteric Allosteric
Rattus norvegicus CK1 CSNK1D KC1D_RAT Casein kinase I isoform delta 1CKJB Active DFGin BLAminus in-in in-in WO4 WO4 WO4 Allosteric Allosteric Allosteric
Saccharomyces cerevisiae OTHER CDC7 CDC7_YEAST Cell division control protein 7 7PT78 Inactive DFGin ABAminus in-out in-in ADP BEF Type1 Allosteric
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ0A None DFGin BLAminus in-in in-none ADP QUE Type1 Allosteric
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ0B None DFGin BLAminus in-in in-none ADP QUE Type1 Allosteric
Salmo salar CMGC P38A A9UJZ9_SALSA mitogen-activated protein kinase 3OHTA Inactive DFGout None in-in none-none 1N1 1N1 Type1.5_Back Allosteric
Salmo salar CMGC P38A A9UJZ9_SALSA mitogen-activated protein kinase 3OHTB Inactive DFGout None in-in none-none 1N1 1N1 Type1.5_Back Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1OA Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1OB Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1OC Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1OD Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1PA Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1PB Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1PC Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 4O1PD Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M11a Active DFGin BLAminus in-in in-none 25A B49 Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M11b Active DFGin BLAminus in-in in-none 25A B49 Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M12b Active DFGin BLAminus in-in in-none 25L J60 Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DSYa Active DFGin BLAminus in-in in-none 25A HFX Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DSYb Active DFGin BLAminus in-in in-none 25A HFX Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DTSa Active DFGin BLAminus in-in in-none 25A 27K Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7DTSb Active DFGin BLAminus in-in in-none 25A 27K Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7ELWa Active DFGin BLAminus in-in in-none 25L MYC Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 7ELWb Active DFGin BLAminus in-in in-none 25L MYC Allosteric Type1
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M12a Active DFGin BLAminus in-in in-none J60 25L Type1 Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M13a Active DFGin BLAminus in-in in-none BWC 25L Type1 Allosteric
Sus scrofa OTHER RNASEL A5H025_PIG Ribonuclease L 6M13b Active DFGin BLAminus in-in in-none BWC 25L Type1 Allosteric