Protein kinases with DFGinter - None conformation

Total number of genes: 35
Total number of chains: 178
AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
DFGinter None 12 78 0 15 2 0 9 16 45 1 4U3YA
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Gene UniprotID Protein PDB Resolution Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 3TWJB 2.9 in-in out-in No_ligand No_ligand
ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 3TWJD 2.9 in-in out-in No_ligand No_ligand
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 7OPOC 2.75 none-none out-out ANP Type1
RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 7OPOG 2.75 out-out out-none ANP Type1
RPS6KA5 KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 1VZOA 1.8 out-out out-out No_ligand No_ligand
RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G76B 3.0 none-none out-none ANP Type1
RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G78A 2.5 none-none out-out ANP Type1
RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G78B 2.5 none-none out-out ANP Type1
RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G76A 3.0 none-none out-in ANP ANP Type1 Allosteric
SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 2R5TA 1.9 none-none out-out ANP Type1
SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 3HDMA 2.6 none-none out-out MMG Type1
SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 3HDNA 3.1 none-none out-out GMG Type1
AURKA AURKA_HUMAN Aurora kinase A 6XKAA 2.65 out-out out-out No_ligand No_ligand
AURKA AURKA_HUMAN Aurora kinase A 2WTVA 2.4 out-out out-out ZZL Type1
AURKA AURKA_HUMAN Aurora kinase A 2WTVB 2.4 out-out out-out ZZL Type1
AURKA AURKA_HUMAN Aurora kinase A 2WTVC 2.4 out-out out-out ZZL Type1
AURKA AURKA_HUMAN Aurora kinase A 2WTVD 2.4 out-out out-out ZZL Type1
AURKA AURKA_HUMAN Aurora kinase A 5EW9A 2.181 out-out out-out 5VC Type1
AURKA AURKA_HUMAN Aurora kinase A 6C2RA 1.96 out-none out-none EG7 Type1
AURKA AURKA_HUMAN Aurora kinase A 6C2TA 1.73 out-out out-out EGJ Type1
AURKA AURKA_HUMAN Aurora kinase A 3W16A 2.8 out-out out-out P9J Type1
AURKA AURKA_HUMAN Aurora kinase A 2J50A 3.0 out-out out-out 627 Type1
AURKA AURKA_HUMAN Aurora kinase A 2J50B 3.0 out-out out-out 627 Type1
AURKA AURKA_HUMAN Aurora kinase A 4C3RA 2.79 out-out out-out ACP Type1
AURKA AURKA_HUMAN Aurora kinase A 4ZTRA 2.85 out-out none-out 4RJ Type1
AURKA AURKA_HUMAN Aurora kinase A 6Z4YA 2.25 out-out out-out Q7Q Type1
AURKA AURKA_HUMAN Aurora kinase A 6C83B 2.55 out-out none-out ACP Type1
AURKA AURKA_HUMAN Aurora kinase A 6CPGA 2.8 out-out none-out 35R Type1
AURKA AURKA_HUMAN Aurora kinase A 6CPGD 2.8 out-out none-out 35R Type1
AURKA AURKA_HUMAN Aurora kinase A 8SSOA 1.97 out-out out-out 627 Type1
AURKA AURKA_HUMAN Aurora kinase A 8SSOD 1.97 out-out out-none 627 Type1
AURKA AURKA_HUMAN Aurora kinase A 1MUOA 2.9 out-out none-out ADN Type1
AURKA AURKA_HUMAN Aurora kinase A 2J4ZA 2.0 out-out out-out 626 Type1
AURKA AURKA_HUMAN Aurora kinase A 3UNZA 2.8 out-out out-out 0BZ Type1
AURKA AURKA_HUMAN Aurora kinase A 3UNZB 2.8 out-out out-out 0BZ Type1
AURKA AURKA_HUMAN Aurora kinase A 3UO6A 2.8 out-out out-out 0BY Type1
AURKA AURKA_HUMAN Aurora kinase A 3UO6B 2.8 out-out out-out 0BY Type1
AURKA AURKA_HUMAN Aurora kinase A 3UOHA 2.8 out-out out-out 0C4 Type1
AURKA AURKA_HUMAN Aurora kinase A 3UOHB 2.8 out-out out-out 0C4 Type1
AURKA AURKA_HUMAN Aurora kinase A 3UOJA 2.9 out-out out-out 0C5 Type1
AURKA AURKA_HUMAN Aurora kinase A 3UOJB 2.9 out-out out-out 0C5 Type1
AURKA AURKA_HUMAN Aurora kinase A 3UOKA 2.951 out-out out-out 0C6 Type1
AURKA AURKA_HUMAN Aurora kinase A 3UOKB 2.951 out-out out-out 0C6 Type1
AURKA AURKA_HUMAN Aurora kinase A 3UOLA 2.4 out-out out-out 0C7 Type1
AURKA AURKA_HUMAN Aurora kinase A 3UOLB 2.4 out-out out-out 0C7 Type1
AURKA AURKA_HUMAN Aurora kinase A 3FDNA 1.9 out-out out-out MMH Type1
AURKA AURKA_HUMAN Aurora kinase A 3K5UA 2.35 out-out out-out PFQ Type1
AURKA AURKA_HUMAN Aurora kinase A 4JBQA 2.3 out-out out-out VX6 Type1
AURKA AURKA_HUMAN Aurora kinase A 3LAUA 2.1 out-out none-none OFI Type1
AURKA AURKA_HUMAN Aurora kinase A 4UZHA 2.0 out-out none-none JVE Type1
AURKA AURKA_HUMAN Aurora kinase A 3H0YA 2.5 out-out none-none 48B Type1
AURKA AURKA_HUMAN Aurora kinase A 3H10A 2.2 out-out out-out 97B Type1
AURKA AURKA_HUMAN Aurora kinase A 3H10B 2.2 out-out out-out 97B Type1
AURKA AURKA_HUMAN Aurora kinase A 3H10D 2.2 out-out out-none 97B Type1
AURKA AURKA_HUMAN Aurora kinase A 3P9JA 2.8 out-out out-out P9J Type1
AURKA AURKA_HUMAN Aurora kinase A 3W10A 2.7 out-out out-out RO9 Type1
AURKA AURKA_HUMAN Aurora kinase A 3R22A 2.9 out-out out-out D37 Type1
AURKA AURKA_HUMAN Aurora kinase A 2BMCA 2.6 out-out out-none MPY Type1
AURKA AURKA_HUMAN Aurora kinase A 2BMCB 2.6 out-out out-none MPY Type1
AURKA AURKA_HUMAN Aurora kinase A 2BMCC 2.6 out-out out-none MPY Type1
AURKA AURKA_HUMAN Aurora kinase A 2BMCD 2.6 out-out out-none MPY Type1
AURKA AURKA_HUMAN Aurora kinase A 2BMCE 2.6 out-out out-none MPY Type1
AURKA AURKA_HUMAN Aurora kinase A 2BMCF 2.6 out-out out-none MPY Type1
AURKA AURKA_HUMAN Aurora kinase A 7FICA 2.32 out-none none-out 5YZ Type1
AURKA AURKA_HUMAN Aurora kinase A 5L8JA 1.68 out-out none-none ADP Type1
AURKA AURKA_HUMAN Aurora kinase A 5L8KA 1.79 out-out out-out ADP Type1
AURKA AURKA_HUMAN Aurora kinase A 5L8LA 1.67 out-out out-out ADP Type1
AURKA AURKA_HUMAN Aurora kinase A 4ZTQA 2.8 out-out out-out 4RM Type1.5_Back
AURKA AURKA_HUMAN Aurora kinase A 4ZTSA 2.9 out-out none-none 4RK Type1.5_Back
AURKA AURKA_HUMAN Aurora kinase A 3EFWA 2.29 out-none none-none AK8 Type1.5_Front
AURKA AURKA_HUMAN Aurora kinase A 3EFWB 2.29 out-out none-none AK8 Type1.5_Front
AURKA AURKA_HUMAN Aurora kinase A 3O50A 2.0 out-out none-none LJE Type1.5_Front
AURKA AURKA_HUMAN Aurora kinase A 3O50B 2.0 out-out none-out LJE Type1.5_Front
AURKA AURKA_HUMAN Aurora kinase A 6HJJA 2.13 out-out out-out G7T Type1.5_Front
AURKB AURKB_HUMAN Aurora kinase B 4AF3A 2.75 out-out none-none VX6 Type1
CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FGBA 2.6 out-out out-out No_ligand No_ligand
CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG9A 2.4 out-out none-none ATP Type1
CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG9B 2.4 out-none none-out ATP Type1
CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 6T6FA 1.97 out-out none-none MMW Type1
CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 6T6FB 1.97 out-out none-none MMW Type1
CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 6T29AAA 1.484 out-out none-none M8Z Type1
CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 6W4OO 4.8 in-none in-in No_ligand No_ligand
CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 6W4PH 6.6 in-none in-in No_ligand No_ligand
CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 3SOAA 3.55 in-none in-in DB8 Type1
MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 4UMTA 1.98 out-out none-out 47W Type1
MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 4UMUA 2.02 out-out none-out 0V0 Type1
PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 4REDA 2.95 out-out out-none No_ligand No_ligand
PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 4REDB 2.95 out-out out-none No_ligand No_ligand
TRIB1 TRIB1_HUMAN Tribbles homolog 1 5CEKA 2.8 out-none none-none No_ligand No_ligand
TRIB1 TRIB1_HUMAN Tribbles homolog 1 5CEMA 2.1 out-none none-out No_ligand No_ligand
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH9A 2.1 in-out none-out IRG 0OQ Allosteric Type3
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3GCPA 2.25 in-in none-none SB2 Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5WJJA 1.6 in-in out-out AQY Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6ANLA 2.0 in-in none-out T75 Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5ML5A 1.9 in-in none-none 1VI Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HUCA 1.8 in-in none-out G97 Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ZS5A 1.6 in-in none-out SB2 Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ZSGA 1.89 in-in none-out T75 Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6HWTA 1.7 in-in out-none GXH Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6HWUA 2.3 in-in none-out GE5 Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6HWVA 1.7 in-in none-none GEW Type1
MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EHVA 1.6 in-none none-out 0SJ 0SJ IRG 0SJ Type3 Allosteric Allosteric Allosteric
MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YKYA 2.52 in-out out-out OWQ Type1
MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YKYD 2.52 out-out out-out OWQ Type1
MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YLCD 2.43 out-out out-out OXW Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5HA 2.33 out-none none-out No_ligand No_ligand
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5BA 2.4 out-out out-out AGS Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKF 2.3 out-out out-out G41 Type1
MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 5YT3A 2.9 out-out none-none ANP Type1
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U3ZA 2.09 out-out out-out No_ligand No_ligand
MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U3YA 1.45 out-out out-out No_ligand No_ligand
SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 4USFA 1.75 out-out out-none 6UI Type1
SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 4USFB 1.75 out-out out-in 6UI Type1
STK25 STK25_HUMAN Serine/threonine-protein kinase 25 4NZWB 3.583 out-out none-in J60 Type1
STK26 STK26_HUMAN Serine/threonine-protein kinase 26 4FZFB 3.64 out-out out-out DKI Type1
TNIK TNIK_HUMAN TRAF2 and NCK-interacting protein kinase 8X88A 2.7 out-out out-out No_ligand No_ligand
TNIK TNIK_HUMAN TRAF2 and NCK-interacting protein kinase 8X88B 2.7 out-out out-out No_ligand No_ligand
ILK ILK_HUMAN Integrin-linked protein kinase 3KMUA 1.8 out-out out-out No_ligand No_ligand
ILK ILK_HUMAN Integrin-linked protein kinase 6MIBA 1.8 out-out out-out No_ligand No_ligand
ILK ILK_HUMAN Integrin-linked protein kinase 3KMWA 2.0 out-out out-out ATP Type1
ILK ILK_HUMAN Integrin-linked protein kinase 3REPA 1.8 out-out out-out ATP Type1
LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHTA 3.5 out-out out-in ATP Type1
LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHTB 3.5 out-out out-in ATP Type1
LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHWA 3.7 out-out out-in ATP Type1
LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LI4A 3.1 out-out out-in ATP Type1
LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO2E 4.13 out-out out-in ATP Type1
LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO8C 3.88 out-out out-in ATP Type1
LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO8E 3.88 out-out out-in ATP Type1
LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9F 3.48 out-out out-in ATP Type1
LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LI3A 3.8 out-out out-in ATP Type1
MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 8GW3B 2.05 out-out out-out No_ligand No_ligand
MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 8GW3C 2.05 out-none none-out No_ligand No_ligand
MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 8GW3D 2.05 out-out none-out No_ligand No_ligand
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GA 2.2 in-out out-in STI 1N1 Allosteric Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GC 2.2 in-none out-in STI 1N1 Allosteric Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2FA 2.7 in-out out-in No_ligand No_ligand
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6BL8A 2.5 in-out out-in PVB Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6BL8B 2.5 in-none out-in PVB Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7YA 2.2 in-out out-in 8IW Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7YB 2.2 in-out out-in 8IW Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7FA 2.45 in-none out-in QEW Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7FB 2.45 in-none out-in QEW Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7HA 2.278 in-none out-in QH9 Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7HB 2.278 in-none out-in QH9 Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4ZOGA 2.3 out-out out-in VX6 Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7CC2A 2.723 out-out out-in FVC Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7CC2B 2.723 in-none out-in FVC Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7DT2A 2.3 in-out out-in HJ9 Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7DT2B 2.3 in-out out-in HJ9 Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2HA 2.0 in-out out-in P16 Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4XEYA 2.891 in-out out-in 1N1 Type1
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4YC8A 2.9 out-none out-in 4B7 Type1.5_Front
ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4YC8B 2.9 out-none out-in 4B7 Type1.5_Front
ABL2 ABL2_HUMAN Tyrosine-protein kinase ABL2 3HMIA 1.65 in-in out-in DKI Type1
BTK BTK_HUMAN Tyrosine-protein kinase BTK 6NFIA 2.41 out-out none-out KLP Type1
DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6Y23A 2.58 in-out out-in No_ligand No_ligand
DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6Y23B 2.58 in-out out-in No_ligand No_ligand
DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6Y23C 2.58 in-out out-in No_ligand No_ligand
DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6BRJA 2.231 in-in out-in VX6 Type1
DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6BSDA 2.606 in-in out-in 1N1 Type1
EGFR EGFR_HUMAN Epidermal growth factor receptor 8H7XB 3.404 in-in out-in No_ligand No_ligand
EGFR EGFR_HUMAN Epidermal growth factor receptor 5XGNB 3.0 in-in out-in No_ligand No_ligand
EGFR EGFR_HUMAN Epidermal growth factor receptor 2JITB 3.1 in-in out-in No_ligand No_ligand
EGFR EGFR_HUMAN Epidermal growth factor receptor 2JIUB 3.05 in-in in-in No_ligand No_ligand
EGFR EGFR_HUMAN Epidermal growth factor receptor 4G5PB 3.17 in-in out-out No_ligand No_ligand
EGFR EGFR_HUMAN Epidermal growth factor receptor 3IKAB 2.9 in-in out-in No_ligand No_ligand
EGFR EGFR_HUMAN Epidermal growth factor receptor 4WD5B 3.3 in-out out-out No_ligand No_ligand
EGFR EGFR_HUMAN Epidermal growth factor receptor 5UWDA 3.06 out-out out-out 8OV Type1
IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1M7NA 2.7 in-out out-in No_ligand No_ligand
IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1M7NB 2.7 in-out out-in No_ligand No_ligand
IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1P4OA 1.5 in-out out-in No_ligand No_ligand
IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1P4OB 1.5 in-out out-in No_ligand No_ligand
KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 1Y6AA 2.1 in-in none-none AAZ Type1
KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 1Y6BA 2.1 in-in none-none AAX Type1
PTK2 FAK1_HUMAN Focal adhesion kinase 1 4EBWA 2.65 in-in none-out 0PF Type1
ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 3ZZWA 2.9 in-out out-in No_ligand No_ligand
ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 4GT4A 2.406 in-out out-in No_ligand No_ligand
ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 4GT4B 2.406 in-in out-in No_ligand No_ligand

All kinases with DFGinter - None conformation

Total number of genes: 43
Total number of chains: 201
AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
DFGinter None 13 90 0 15 2 0 9 16 53 3 4U3YA
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Gene UniprotID Protein PDB Resolution Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UJGA 2.6 out-out out-out No_ligand No_ligand
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBA 2.567 out-out none-none No_ligand No_ligand
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBB 2.567 out-out none-out No_ligand No_ligand
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBD 2.567 out-out none-none No_ligand No_ligand
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBF 2.567 out-out none-none No_ligand No_ligand
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UC4A 2.3 out-out none-out No_ligand No_ligand
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UC4B 2.3 out-out none-out No_ligand No_ligand
Bos taurus GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4YB 7.509 in-out in-in No_ligand No_ligand
Corynebacterium glutamicum PKNG Q8NM29_CORGL Serine/threonine protein kinases 7MXJA 1.92 out-out in-in MAP Type1
Corynebacterium glutamicum PKNG Q8NM29_CORGL Serine/threonine protein kinases 7MXKA 1.99 out-out in-in MAP Type1
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 2QQ7B 2.38 none-none none-none SR2 Type1
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3LOKB 2.48 none-none none-none DJK Type1
Homo sapiens ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 3TWJB 2.9 in-in out-in No_ligand No_ligand
Homo sapiens ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 3TWJD 2.9 in-in out-in No_ligand No_ligand
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 7OPOC 2.75 none-none out-out ANP Type1
Homo sapiens RPS6KA3 KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 7OPOG 2.75 out-out out-none ANP Type1
Homo sapiens RPS6KA5 KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 1VZOA 1.8 out-out out-out No_ligand No_ligand
Homo sapiens RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G76B 3.0 none-none out-none ANP Type1
Homo sapiens RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G78A 2.5 none-none out-out ANP Type1
Homo sapiens RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G78B 2.5 none-none out-out ANP Type1
Homo sapiens RPS6KA6 KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 6G76A 3.0 none-none out-in ANP ANP Type1 Allosteric
Homo sapiens SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 2R5TA 1.9 none-none out-out ANP Type1
Homo sapiens SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 3HDMA 2.6 none-none out-out MMG Type1
Homo sapiens SGK1 SGK1_HUMAN Serine/threonine-protein kinase Sgk1 3HDNA 3.1 none-none out-out GMG Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 6XKAA 2.65 out-out out-out No_ligand No_ligand
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2WTVA 2.4 out-out out-out ZZL Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2WTVB 2.4 out-out out-out ZZL Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2WTVC 2.4 out-out out-out ZZL Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2WTVD 2.4 out-out out-out ZZL Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 5EW9A 2.181 out-out out-out 5VC Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 6C2RA 1.96 out-none out-none EG7 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 6C2TA 1.73 out-out out-out EGJ Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3W16A 2.8 out-out out-out P9J Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2J50A 3.0 out-out out-out 627 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2J50B 3.0 out-out out-out 627 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 4C3RA 2.79 out-out out-out ACP Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 4ZTRA 2.85 out-out none-out 4RJ Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 6Z4YA 2.25 out-out out-out Q7Q Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 6C83B 2.55 out-out none-out ACP Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 6CPGA 2.8 out-out none-out 35R Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 6CPGD 2.8 out-out none-out 35R Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 8SSOA 1.97 out-out out-out 627 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 8SSOD 1.97 out-out out-none 627 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 1MUOA 2.9 out-out none-out ADN Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2J4ZA 2.0 out-out out-out 626 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3UNZA 2.8 out-out out-out 0BZ Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3UNZB 2.8 out-out out-out 0BZ Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3UO6A 2.8 out-out out-out 0BY Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3UO6B 2.8 out-out out-out 0BY Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3UOHA 2.8 out-out out-out 0C4 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3UOHB 2.8 out-out out-out 0C4 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3UOJA 2.9 out-out out-out 0C5 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3UOJB 2.9 out-out out-out 0C5 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3UOKA 2.951 out-out out-out 0C6 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3UOKB 2.951 out-out out-out 0C6 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3UOLA 2.4 out-out out-out 0C7 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3UOLB 2.4 out-out out-out 0C7 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3FDNA 1.9 out-out out-out MMH Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3K5UA 2.35 out-out out-out PFQ Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 4JBQA 2.3 out-out out-out VX6 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3LAUA 2.1 out-out none-none OFI Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 4UZHA 2.0 out-out none-none JVE Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3H0YA 2.5 out-out none-none 48B Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3H10A 2.2 out-out out-out 97B Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3H10B 2.2 out-out out-out 97B Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3H10D 2.2 out-out out-none 97B Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3P9JA 2.8 out-out out-out P9J Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3W10A 2.7 out-out out-out RO9 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3R22A 2.9 out-out out-out D37 Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2BMCA 2.6 out-out out-none MPY Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2BMCB 2.6 out-out out-none MPY Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2BMCC 2.6 out-out out-none MPY Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2BMCD 2.6 out-out out-none MPY Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2BMCE 2.6 out-out out-none MPY Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 2BMCF 2.6 out-out out-none MPY Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 7FICA 2.32 out-none none-out 5YZ Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 5L8JA 1.68 out-out none-none ADP Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 5L8KA 1.79 out-out out-out ADP Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 5L8LA 1.67 out-out out-out ADP Type1
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 4ZTQA 2.8 out-out out-out 4RM Type1.5_Back
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 4ZTSA 2.9 out-out none-none 4RK Type1.5_Back
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3EFWA 2.29 out-none none-none AK8 Type1.5_Front
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3EFWB 2.29 out-out none-none AK8 Type1.5_Front
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3O50A 2.0 out-out none-none LJE Type1.5_Front
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 3O50B 2.0 out-out none-out LJE Type1.5_Front
Homo sapiens AURKA AURKA_HUMAN Aurora kinase A 6HJJA 2.13 out-out out-out G7T Type1.5_Front
Homo sapiens AURKB AURKB_HUMAN Aurora kinase B 4AF3A 2.75 out-out none-none VX6 Type1
Homo sapiens CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FGBA 2.6 out-out out-out No_ligand No_ligand
Homo sapiens CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG9A 2.4 out-out none-none ATP Type1
Homo sapiens CAMK1 KCC1A_HUMAN Calcium/calmodulin-dependent protein kinase type 1 4FG9B 2.4 out-none none-out ATP Type1
Homo sapiens CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 6T6FA 1.97 out-out none-none MMW Type1
Homo sapiens CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 6T6FB 1.97 out-out none-none MMW Type1
Homo sapiens CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 6T29AAA 1.484 out-out none-none M8Z Type1
Homo sapiens CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 6W4OO 4.8 in-none in-in No_ligand No_ligand
Homo sapiens CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 6W4PH 6.6 in-none in-in No_ligand No_ligand
Homo sapiens CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 3SOAA 3.55 in-none in-in DB8 Type1
Homo sapiens MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 4UMTA 1.98 out-out none-out 47W Type1
Homo sapiens MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 4UMUA 2.02 out-out none-out 0V0 Type1
Homo sapiens PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 4REDA 2.95 out-out out-none No_ligand No_ligand
Homo sapiens PRKAA1 AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 4REDB 2.95 out-out out-none No_ligand No_ligand
Homo sapiens TRIB1 TRIB1_HUMAN Tribbles homolog 1 5CEKA 2.8 out-none none-none No_ligand No_ligand
Homo sapiens TRIB1 TRIB1_HUMAN Tribbles homolog 1 5CEMA 2.1 out-none none-out No_ligand No_ligand
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH9A 2.1 in-out none-out IRG 0OQ Allosteric Type3
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3GCPA 2.25 in-in none-none SB2 Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5WJJA 1.6 in-in out-out AQY Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6ANLA 2.0 in-in none-out T75 Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5ML5A 1.9 in-in none-none 1VI Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HUCA 1.8 in-in none-out G97 Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ZS5A 1.6 in-in none-out SB2 Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ZSGA 1.89 in-in none-out T75 Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6HWTA 1.7 in-in out-none GXH Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6HWUA 2.3 in-in none-out GE5 Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 6HWVA 1.7 in-in none-none GEW Type1
Homo sapiens MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EHVA 1.6 in-none none-out 0SJ 0SJ IRG 0SJ Type3 Allosteric Allosteric Allosteric
Homo sapiens MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YKYA 2.52 in-out out-out OWQ Type1
Homo sapiens MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YKYD 2.52 out-out out-out OWQ Type1
Homo sapiens MAPK6 MK06_HUMAN Mitogen-activated protein kinase 6 6YLCD 2.43 out-out out-out OXW Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5HA 2.33 out-none none-out No_ligand No_ligand
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5BA 2.4 out-out out-out AGS Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKF 2.3 out-out out-out G41 Type1
Homo sapiens MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 5YT3A 2.9 out-out none-none ANP Type1
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U3ZA 2.09 out-out out-out No_ligand No_ligand
Homo sapiens MAP4K4 M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 4U3YA 1.45 out-out out-out No_ligand No_ligand
Homo sapiens SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 4USFA 1.75 out-out out-none 6UI Type1
Homo sapiens SLK SLK_HUMAN STE20-like serine/threonine-protein kinase 4USFB 1.75 out-out out-in 6UI Type1
Homo sapiens STK25 STK25_HUMAN Serine/threonine-protein kinase 25 4NZWB 3.583 out-out none-in J60 Type1
Homo sapiens STK26 STK26_HUMAN Serine/threonine-protein kinase 26 4FZFB 3.64 out-out out-out DKI Type1
Homo sapiens TNIK TNIK_HUMAN TRAF2 and NCK-interacting protein kinase 8X88A 2.7 out-out out-out No_ligand No_ligand
Homo sapiens TNIK TNIK_HUMAN TRAF2 and NCK-interacting protein kinase 8X88B 2.7 out-out out-out No_ligand No_ligand
Homo sapiens ILK ILK_HUMAN Integrin-linked protein kinase 3KMUA 1.8 out-out out-out No_ligand No_ligand
Homo sapiens ILK ILK_HUMAN Integrin-linked protein kinase 6MIBA 1.8 out-out out-out No_ligand No_ligand
Homo sapiens ILK ILK_HUMAN Integrin-linked protein kinase 3KMWA 2.0 out-out out-out ATP Type1
Homo sapiens ILK ILK_HUMAN Integrin-linked protein kinase 3REPA 1.8 out-out out-out ATP Type1
Homo sapiens LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHTA 3.5 out-out out-in ATP Type1
Homo sapiens LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHTB 3.5 out-out out-in ATP Type1
Homo sapiens LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LHWA 3.7 out-out out-in ATP Type1
Homo sapiens LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LI4A 3.1 out-out out-in ATP Type1
Homo sapiens LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO2E 4.13 out-out out-in ATP Type1
Homo sapiens LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO8C 3.88 out-out out-in ATP Type1
Homo sapiens LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO8E 3.88 out-out out-in ATP Type1
Homo sapiens LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 8FO9F 3.48 out-out out-in ATP Type1
Homo sapiens LRRK2 LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 7LI3A 3.8 out-out out-in ATP Type1
Homo sapiens MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 8GW3B 2.05 out-out out-out No_ligand No_ligand
Homo sapiens MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 8GW3C 2.05 out-none none-out No_ligand No_ligand
Homo sapiens MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 8GW3D 2.05 out-out none-out No_ligand No_ligand
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GA 2.2 in-out out-in STI 1N1 Allosteric Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7N9GC 2.2 in-none out-in STI 1N1 Allosteric Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2FA 2.7 in-out out-in No_ligand No_ligand
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6BL8A 2.5 in-out out-in PVB Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 6BL8B 2.5 in-none out-in PVB Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7YA 2.2 in-out out-in 8IW Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7W7YB 2.2 in-out out-in 8IW Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7FA 2.45 in-none out-in QEW Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7FB 2.45 in-none out-in QEW Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7HA 2.278 in-none out-in QH9 Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 8H7HB 2.278 in-none out-in QH9 Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4ZOGA 2.3 out-out out-in VX6 Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7CC2A 2.723 out-out out-in FVC Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7CC2B 2.723 in-none out-in FVC Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7DT2A 2.3 in-out out-in HJ9 Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 7DT2B 2.3 in-out out-in HJ9 Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2HA 2.0 in-out out-in P16 Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4XEYA 2.891 in-out out-in 1N1 Type1
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4YC8A 2.9 out-none out-in 4B7 Type1.5_Front
Homo sapiens ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 4YC8B 2.9 out-none out-in 4B7 Type1.5_Front
Homo sapiens ABL2 ABL2_HUMAN Tyrosine-protein kinase ABL2 3HMIA 1.65 in-in out-in DKI Type1
Homo sapiens BTK BTK_HUMAN Tyrosine-protein kinase BTK 6NFIA 2.41 out-out none-out KLP Type1
Homo sapiens DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6Y23A 2.58 in-out out-in No_ligand No_ligand
Homo sapiens DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6Y23B 2.58 in-out out-in No_ligand No_ligand
Homo sapiens DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6Y23C 2.58 in-out out-in No_ligand No_ligand
Homo sapiens DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6BRJA 2.231 in-in out-in VX6 Type1
Homo sapiens DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 6BSDA 2.606 in-in out-in 1N1 Type1
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 8H7XB 3.404 in-in out-in No_ligand No_ligand
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 5XGNB 3.0 in-in out-in No_ligand No_ligand
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 2JITB 3.1 in-in out-in No_ligand No_ligand
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 2JIUB 3.05 in-in in-in No_ligand No_ligand
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 4G5PB 3.17 in-in out-out No_ligand No_ligand
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 3IKAB 2.9 in-in out-in No_ligand No_ligand
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 4WD5B 3.3 in-out out-out No_ligand No_ligand
Homo sapiens EGFR EGFR_HUMAN Epidermal growth factor receptor 5UWDA 3.06 out-out out-out 8OV Type1
Homo sapiens IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1M7NA 2.7 in-out out-in No_ligand No_ligand
Homo sapiens IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1M7NB 2.7 in-out out-in No_ligand No_ligand
Homo sapiens IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1P4OA 1.5 in-out out-in No_ligand No_ligand
Homo sapiens IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 1P4OB 1.5 in-out out-in No_ligand No_ligand
Homo sapiens KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 1Y6AA 2.1 in-in none-none AAZ Type1
Homo sapiens KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 1Y6BA 2.1 in-in none-none AAX Type1
Homo sapiens PTK2 FAK1_HUMAN Focal adhesion kinase 1 4EBWA 2.65 in-in none-out 0PF Type1
Homo sapiens ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 3ZZWA 2.9 in-out out-in No_ligand No_ligand
Homo sapiens ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 4GT4A 2.406 in-out out-in No_ligand No_ligand
Homo sapiens ROR2 ROR2_HUMAN Tyrosine-protein kinase transmembrane receptor ROR2 4GT4B 2.406 in-in out-in No_ligand No_ligand
Mus musculus AURKA AURKA_MOUSE Aurora kinase A 3DAJA 2.0 out-out none-none FXG Type1
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK7A 2.01 in-in out-in SX7 Type1
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK6A 2.02 in-in out-in SX7 Type1
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK6B 2.02 in-none out-in SX7 Type1
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK3A 2.02 in-in out-in SX7 Type1
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK3B 2.02 in-in out-in SX7 Type1
Rattus norvegicus MUSK MUSK_RAT Muscle, skeletal receptor tyrosine protein kinase 1LUFA 2.05 in-in out-in No_ligand No_ligand
Saccharomyces cerevisiae SNF1 SNF1_YEAST Carbon catabolite-derepressing protein kinase 3MN3A 2.38 out-out none-out No_ligand No_ligand
Saccharum officinarum SAPK10 A0A238LNS4_9POAL non-specific serine/threonine protein kinase 5WAXA 2.0 out-out none-none No_ligand No_ligand
Saccharum officinarum SAPK10 A0A238LNS4_9POAL non-specific serine/threonine protein kinase 5WAXB 2.0 out-none none-out No_ligand No_ligand
Schizosaccharomyces pombe SSP2 SNF1_SCHPO SNF1-like protein kinase ssp2 3H4JB 2.8 out-out out-out No_ligand No_ligand

All kinases with DFGinter - None conformation

Total number of genes: 10
Total number of chains: 23
AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
DFGinter None 1 12 0 0 0 0 0 0 8 2 3H4JB
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Gene UniprotID Protein PDB Resolution Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UJGA 2.6 out-out out-out No_ligand No_ligand
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBA 2.567 out-out none-none No_ligand No_ligand
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBB 2.567 out-out none-out No_ligand No_ligand
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBD 2.567 out-out none-none No_ligand No_ligand
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UDBF 2.567 out-out none-none No_ligand No_ligand
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UC4A 2.3 out-out none-out No_ligand No_ligand
Arabidopsis thaliana SRK2E SRK2E_ARATH Serine/threonine-protein kinase SRK2E 3UC4B 2.3 out-out none-out No_ligand No_ligand
Bos taurus GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4YB 7.509 in-out in-in No_ligand No_ligand
Corynebacterium glutamicum PKNG Q8NM29_CORGL Serine/threonine protein kinases 7MXJA 1.92 out-out in-in MAP Type1
Corynebacterium glutamicum PKNG Q8NM29_CORGL Serine/threonine protein kinases 7MXKA 1.99 out-out in-in MAP Type1
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 2QQ7B 2.38 none-none none-none SR2 Type1
Gallus gallus SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3LOKB 2.48 none-none none-none DJK Type1
Mus musculus AURKA AURKA_MOUSE Aurora kinase A 3DAJA 2.0 out-out none-none FXG Type1
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK7A 2.01 in-in out-in SX7 Type1
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK6A 2.02 in-in out-in SX7 Type1
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK6B 2.02 in-none out-in SX7 Type1
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK3A 2.02 in-in out-in SX7 Type1
Mus musculus ABL1 ABL1_MOUSE Tyrosine-protein kinase ABL1 3DK3B 2.02 in-in out-in SX7 Type1
Rattus norvegicus MUSK MUSK_RAT Muscle, skeletal receptor tyrosine protein kinase 1LUFA 2.05 in-in out-in No_ligand No_ligand
Saccharomyces cerevisiae SNF1 SNF1_YEAST Carbon catabolite-derepressing protein kinase 3MN3A 2.38 out-out none-out No_ligand No_ligand
Saccharum officinarum SAPK10 A0A238LNS4_9POAL non-specific serine/threonine protein kinase 5WAXA 2.0 out-out none-none No_ligand No_ligand
Saccharum officinarum SAPK10 A0A238LNS4_9POAL non-specific serine/threonine protein kinase 5WAXB 2.0 out-none none-out No_ligand No_ligand
Schizosaccharomyces pombe SSP2 SNF1_SCHPO SNF1-like protein kinase ssp2 3H4JB 2.8 out-out out-out No_ligand No_ligand