3LW0

IGF1R (Insulin-like growth factor 1 receptor)
Group: TYR
Uniprot: IGF1R_HUMAN
Organism: Homo sapiens
Domain boundary: 999 - 1268
Resolu: 1.79

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric 983 - 1286 3
B Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric 983 - 1286 3
C Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric 983 - 1286 3
D Inactive DFGout None in-out out-in CCX CCX Type3 Allosteric 983 - 1286 3
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
       992       1002       1012       1022 
AADVYVPDEW EVAREKITMS RELGQGSFGM VYEGVAKGVV 
      1032       1042       1052       1062 
KDEPETRVAI KTVNEAASMR ERIEFLNEAS VMKEFNCHHV 
      1072       1082       1092       1102 
VRLLGVVSQG QPTLVIMELM TRGDLKSYLR SLRPamannp 
      1112       1122       1132       1142 
vlaPPSLSKM IQMAGEIADG MAYLNANKFV HRDLAARNCM 
      1152       1162       1172       1182 
VAEDFTVKIG DFGMTRDIYE TDYYRKggkG LLPVRWMSPE 
      1192       1202       1212       1222 
SLKDGVFTTY SDVWSFGVVL WEIATLAEQP YQGLSNEQVL 
      1232       1242       1252       1262 
RFVMEGGLLD KPDNCPDMLF ELMRMCWQYN PKMRPSFLEI 
      1272       1282 
ISSIKEEMEP GFREVSFYYS EENK
Lower-case residues are disordered in structure.
Mutations: E1097A,E1099A
Phosphorylation: None